98 citations
,
March 2019 in “Frontiers in immunology” Damaging mutations in NFKB2 cause a severe and distinct form of primary immunodeficiency with early-onset and often ACTH-deficiency.
90 citations
,
December 2008 in “Journal of Investigative Dermatology” Thyroid-stimulating hormone affects hair follicles but doesn't change hair growth or color.
82 citations
,
July 2012 in “Brain pathology” High LGR5 levels in glioblastoma indicate poor prognosis and are essential for cancer stem cell survival.
81 citations
,
June 2006 in “Experimental Neurology” Neurosteroids may help prevent seizures in epilepsy.
72 citations
,
November 2002 in “Journal of Investigative Dermatology” Estrogen receptor α controls hair growth cycles and skin thickness in male mice.
70 citations
,
February 2016 in “EMBO reports” Scientists found a specific group of itch-sensing nerve cells in mice important for feeling itch but not for sensing heat or touch.
66 citations
,
February 2007 in “The journal of investigative dermatology/Journal of investigative dermatology” Adenosine may promote hair growth by increasing FGF-7 levels in dermal papilla cells.
56 citations
,
August 2019 in “Clinical, Cosmetic and Investigational Dermatology” The document concludes that Telogen Effluvium is a hair loss disorder that can be assessed with the modified wash test and may be treated with clobetasol foam, with patient management being important.
49 citations
,
October 2022 in “PubMed” Hair loss is influenced by genetics, diet, and lifestyle, but more research is needed on nutrition's role.
43 citations
,
January 2016 in “Cellular physiology and biochemistry” Epidermal Growth Factor helps hair follicle cells grow and move by activating a specific cell signaling pathway.
42 citations
,
April 2021 in “JCI insight” Blocking JAK3 signaling can reverse hair loss from alopecia areata.
36 citations
,
February 2016 in “British journal of pharmacology” Sirtuin 1 could be a potential drug target for treating hypertrophic scars.
28 citations
,
February 2021 in “Stem Cell Research & Therapy” Placental cell medium boosts blood vessel growth in lab tests.
27 citations
,
May 2019 in “Cosmetics” The hair cuticle is made of tough proteins that protect the hair, but more research is needed to fully understand its structure.
27 citations
,
June 2010 in “Journal of the American Academy of Dermatology” Excessive selenium in supplements can cause hair loss and nail issues.
26 citations
,
June 2011 in “Molecular Medicine” Progesterone significantly reduces neuroblastoma tumor growth without harming healthy cells.
18 citations
,
January 2021 in “Theranostics” The targeted nanohybrids effectively reduced psoriasis symptoms and improved skin health.
18 citations
,
December 2017 in “Medicine” Adding celecoxib to chemotherapy improves survival and quality of life for gastric cancer patients with positive COX-2.
15 citations
,
October 2024 in “Nutrients” A plant-based diet and certain probiotics may improve skin health and reduce inflammation.
15 citations
,
March 2015 in “PloS one” Scientists restored fertility in male mice lacking a key fertility gene by using a modified gene.
14 citations
,
March 2022 in “Journal of Biomedical Science” Cyanidin 3-O-arabinoside may help treat a common form of hair loss by protecting cells against aging and improving cell function.
12 citations
,
January 2023 in “Indian Dermatology Online Journal” Diagnosing and managing children's hair shaft disorders is challenging but essential.
12 citations
,
April 2019 in “Scientific Reports” A protein called HMGB1 helps hair grow by affecting prostaglandin metabolism.
11 citations
,
December 2024 in “Stem Cell Research & Therapy” Exosomes from umbilical cord stem cells help heal complex perianal fistulas in rats.
9 citations
,
June 2023 in “Cells” Certain natural and synthetic compounds may help treat inflammatory skin diseases by targeting a specific signaling pathway.
9 citations
,
July 2022 in “EMBO molecular medicine” Blocking certain immune signals can reduce skin damage from radiation therapy.
8 citations
,
August 2023 in “Journal of Investigative Dermatology” Corin speeds up wound healing by helping skin cells move and grow.
8 citations
,
March 2022 in “Frontiers in Cell and Developmental Biology” Human hair follicle stem cells can help treat bone loss in osteoporosis.
7 citations
,
March 2023 in “Frontiers in Veterinary Science” Camelina oil can improve dog coat quality like flaxseed and canola oils.
6 citations
,
November 2023 in “Chinese Medicine” Xinyang Tablet improves heart function in sepsis by reducing inflammation.