57 citations
,
February 2018 in “Journal of the American Academy of Dermatology” Biotin supplements are not proven to improve hair or nails and may interfere with medical tests.
September 1998 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology” The document concludes that individualized treatments for hair issues are effective, certain hair changes can indicate neurocutaneous diseases, specific lotions improve skin health, laser hair removal works but needs more study on long-term effects, men's cosmetics are diverse, peeling is effective but can have side effects, and facial pigmentation is often due to overactive skin cells.
6 citations
,
April 2013 in “International Journal of Dermatology” Valproic acid helped hair growth in alopecia patient; more research needed.
August 2010 in “Journal of The American Academy of Dermatology” The document explains the diagnosis and characteristics of woolly hair nevus and alopecia neoplastica.
78 citations
,
January 2017 in “Skin appendage disorders” Biotin supplements may improve hair and nail growth in people with certain deficiencies or conditions, but there's not enough evidence to recommend it for healthy individuals.
37 citations
,
February 2014 in “Journal of Dermatology” Valproic acid increases hair count in men with hair loss.
30 citations
,
May 2004 in “Journal der Deutschen Dermatologischen Gesellschaft” The document concludes that early diagnosis and treatment are crucial for children with hair loss to prevent permanent damage, although not all conditions can be effectively treated.
11 citations
,
February 2019 in “Journal of Cosmetic Dermatology” Low zinc and biotin levels linked to male hair loss; supplements may help.
2 citations
,
July 2018 in “Elsevier eBooks” Some supplements may help with hair loss, but there's not enough strong evidence to recommend them without doctor advice.
Topical valproate can effectively promote hair growth.
February 2025 in “International Journal of Morphology” Vitamin E can reduce the negative effects of valproic acid on hair and skin development.
March 2000 in “Preventive Nutrition and Food Science” Whalgichan improved hair growth, reduced hair loss, and enhanced cholesterol and lipid metabolism without side effects.
4 citations
,
January 2018 in “International Journal of Trichology” A rare genetic disease causes sparse hair and early blindness due to a gene mutation.
4 citations
,
October 1993 in “PubMed” Valproic acid can cause mild side effects like anorexia and hair loss in some epileptic patients.
24 citations
,
May 2017 in “PubMed” Biotin supplements for hair improvement are popular without scientific proof of effectiveness.
September 2019 in “PubMed” The conclusion suggests using a science-based, multi-targeted treatment for hair loss instead of just biotin.
71 citations
,
January 2016 in “International Journal of Trichology” Biotin deficiency is not a major cause of hair loss in women, so biotin supplements are not likely to be an effective hair loss treatment.
6 citations
,
January 2020 5 citations
,
January 2020 53 citations
,
March 2003 in “Journal of Investigative Dermatology” Human skin cells have a high-affinity system for biotin transport, crucial for skin health.
72 citations
,
October 1988 in “Archives of Disease in Childhood” Biotin treatment improves symptoms of biotinidase deficiency, but some neurological damage may be permanent.
31 citations
,
December 1997 in “Developmental Medicine & Child Neurology” Biotinidase deficiency can cause vision and walking problems in children and can improve with biotin treatment.
12 citations
,
September 2011 in “BMJ Case Reports” Quick diagnosis and biotin treatment can dramatically improve biotinidase deficiency symptoms.
10 citations
,
January 1992 in “Screening” Newborn screening for biotinidase deficiency is effective in preventing severe complications.
4 citations
,
July 2019 in “Clinical and experimental dermatology” Early diagnosis and biotin treatment are crucial for infants with biotinidase deficiency to prevent severe complications.
1 citations
,
November 2011 in “Turkish Journal of Dermatology” Biotin treatment improved hair and skin issues in a child with biotinidase deficiency.
March 2023 in “Mağallaẗ wāsit li-l-ʿulūm wa-al-ṭibb” A rare biotin deficiency in an Iraqi family caused severe symptoms but was successfully treated with lifelong biotin.
June 1987 in “Pediatric Neurology Briefs” Biotinidase deficiency can cause symptoms like sleepiness, hair loss, and seizures.
12 citations
,
January 1987 in “Ophthalmic Paediatrics and Genetics” Early diagnosis and treatment of biotinidase deficiency are crucial to prevent vision problems.