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Biotin supplements increased biotin levels but did not significantly prevent hair loss in rats on valproic acid.

Valproic acid may cause hair loss by reducing biotinidase enzyme activity in rats.

A rare biotin deficiency in an Iraqi family caused severe symptoms but was successfully treated with lifelong biotin.

Biotin supplements did not significantly reduce hair loss in rats on valproic acid.

Valproate can cause both hair loss and curly hair in bipolar disorder patients.

Valproic acid does not change biotinidase enzyme activity in children's blood.

Two enzyme defects in biotin metabolism cause severe skin, hair, and metabolic issues.

Early detection and biotin treatment improve outcomes for biotinidase deficiency.

Valproic acid treatment increases a specific acid in urine by blocking an enzyme, possibly causing skin rash and hair loss.

Valproic acid and carbamazepine do not change biotin or biotinidase levels but may lower zinc levels, still within normal range.

Children taking higher doses of valproic acid had lower biotinidase activity, which may lead to biotin deficiency, but biotin supplements could help.

Biotinidase deficiency can cause symptoms like sleepiness, hair loss, and seizures.

Two genetic disorders affect biotin metabolism, causing severe skin, hair, and metabolic issues.

An infant with seizures and hair loss was diagnosed with biotinidase deficiency and treated successfully with biotin.

Biotinidase deficiency has various symptoms and can be treated with biotin supplements.

Biotinidase deficiency can mimic other conditions, making early diagnosis and treatment crucial to prevent lasting issues.

Biotin supplements improved skin and hair problems in a girl with biotinidase deficiency.

Early biotin treatment can reverse symptoms of congenital biotinidase deficiency.

Some children in Malaysia with symptoms have either profound or partial biotinidase deficiency, and early testing and treatment are important.

Valproic acid treatment may cause temporary hair loss due to reduced zinc and biotinidase levels, which tend to normalize after 6 months.

Biotin and biotinidase are essential to prevent health issues, and deficiencies require lifelong supplementation.

Biotin supplements are not proven to improve hair or nails and may interfere with medical tests.

The study found two new mutations in a Chinese patient with severe biotinidase deficiency.

Valproic acid treatment may cause hair loss due to reduced biotinidase activity.

The document explains the genetic causes and characteristics of inherited hair disorders.

Children with partial biotinidase deficiency are healthy at birth but may develop symptoms that improve with biotin therapy.

Biotin deficiency in patients on total parenteral nutrition can cause serious symptoms but can be treated with biotin supplements.

Biotin is important for health, but taking extra usually doesn't help unless you're deficient.

Biotin supplementation during isotretinoin treatment for acne may help maintain skin hydration and improve hair growth.

Biotin supplements may improve hair and nail growth in people with certain deficiencies or conditions, but there's not enough evidence to recommend it for healthy individuals.