March 2008 in “British Journal of Pharmacology” Enzymes play crucial roles in metabolism, health, and disease management.
64 citations
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March 2005 in “Journal of Investigative Dermatology” Brain-Derived Neurotrophic Factor (BDNF) slows down hair growth and promotes hair follicle regression.
September 2017 in “Hair transplant forum international” Biotin is popular for hair loss, but there's little scientific proof it works.
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December 2022 in “Pharmaceutics” The enzyme pyruvate kinase M2 helps hair regrowth and could be a potential treatment for hair loss.
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January 1994 in “PubMed” 118 citations
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January 2004 in “European Journal of Cell Biology” Balanced protease activity is crucial for healthy skin and hair development.
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August 2014 in “Steroids” Fermentation of Finasteride with Ocimum sanctum L. creates new metabolite that inhibits tyrosinase.
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December 1997 in “Journal of Biological Chemistry” A genetic mutation in the hHa1 gene creates a smaller, but still functional, hair protein without causing hair problems.
January 2026 in “International Journal of Biological Macromolecules” 1 citations
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June 2022 in “Tidsskrift for Den norske legeforening” A young boy's uncombable hair is due to a rare genetic condition that usually improves over time.
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June 2015 in “British Journal of Pharmacology” Betulinic acid can help treat hepatitis C by stopping virus replication.
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February 1991 in “Journal of Biological Chemistry”
April 2024 in “Anais brasileiros de dermatologia/Anais Brasileiros de Dermatologia” Using both minoxidil and biotin together increased hair growth more than using either one alone.
April 2022 in “UNESP Institutional Repository (São Paulo State University)” Using both topical minoxidil and oral biotin together significantly boosts hair growth and density.
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July 2010 in “The FEBS journal” The study found a specific peptide that helps detect TGase 3 activity in skin and hair follicles.
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May 2016 in “Pharmaceutical Biology” Aspergillus niger culture creates two finasteride derivatives with enzyme-inhibiting effects.
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January 1989 Tay syndrome is a unique genetic disorder causing skin, hair, and developmental issues.
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February 2004 in “Biopolymers” 4-(4-Phenoxybenzoyl)benzoic acid derivatives can both increase and decrease certain types of reactive oxygen species, and may be relevant to hair loss.
November 2025 in “Probiotics and Antimicrobial Proteins” 6 citations
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January 2001 in “Bioscience Biotechnology and Biochemistry” Ubiquitin, a protein, is found in hair, nails, and skin.
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January 1984 in “Molecular and Cellular Biochemistry” 13 citations
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January 1997 in “Biochemical Pharmacology” Human liver enzyme DHEA ST helps process minoxidil.
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September 2019 in “Experimental cell research” BMP2 helps hair follicle stem cells become specialized by increasing PTEN, which causes autophagy.
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April 2013 in “International Journal of Dermatology” Valproic acid helped hair growth in alopecia patient; more research needed.
August 2010 in “Journal of The American Academy of Dermatology” The document explains the diagnosis and characteristics of woolly hair nevus and alopecia neoplastica.