7 citations
,
July 2019 in “International Journal of Molecular Sciences” PGA-4HGF may help treat hair loss by activating hair growth pathways and extending the hair growth phase.
February 1985 in “PubMed” 
3 citations
,
June 2017 in “Journal of Biomaterials Applications” Keratin extract from human hair was found to promote hair growth in mice.
54 citations
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January 1984 in “Molecular and Cellular Biochemistry” 5 citations
,
May 2023 in “Microbial Cell Factories” A stable, active version of a growth factor was made in bacteria, showing promise for medical use.
3 citations
,
March 2016 in “Journal of Cosmetic Dermatology” GPIGS peptide increases thick hair growth in balding Japanese men.
16 citations
,
January 2017 in “Physical chemistry chemical physics/PCCP. Physical chemistry chemical physics” The 3D structure of a key hair protein was modeled, revealing specific helical structures and stabilization features.
August 2018 in “Journal of the American Academy of Dermatology” Biotin treatment for hair, nail, and skin disorders has weak evidence and should not be recommended unless new research shows clear benefits.
December 2023 in “Chiwi'saeng'gwa haghoeji” Hair keratin protein might help heal mouth wounds faster.
4 citations
,
August 2018 in “Journal of The American Academy of Dermatology” The authors agree that biotin may help certain hair disorders but lacks evidence for use in healthy people and call for more research.
December 2015 in “OPAL (Open@LaTrobe) (La Trobe University)” QLT0267 stops hair follicle cell growth and movement.
18 citations
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June 2017 in “Proceedings of the National Academy of Sciences of the United States of America” A gene called Gk5 controls lipid production in the skin and affects hair growth.
April 2016 in “Journal of Investigative Dermatology” Boosting HGF signaling could improve the creation of hair follicles in lab-made skin.
78 citations
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January 2017 in “Skin appendage disorders” Biotin supplements may improve hair and nail growth in people with certain deficiencies or conditions, but there's not enough evidence to recommend it for healthy individuals.
5 citations
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May 2019 in “Cureus” Taking biotin supplements can cause incorrect thyroid test results, leading to wrong diagnoses.
29 citations
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July 1996 in “Acta Paediatrica” Biotin should be added to Japanese amino acid formula to prevent deficiency.
April 2016 in “한국고분자학회 학술대회 연구논문 초록집” 6 citations
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January 2016 in “Pediatrics international” Japanese infants fed hydrolysate formula may have low biotin levels.
Biotin can help improve hair condition and reduce hair loss.
77 citations
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February 2001 in “Journal of Dermatological Science” HGF activator helps convert HGF to its active form, promoting hair growth.
December 2000 in “日本組織細胞化学会総会プログラムおよび抄録集” July 2007 in “Manuals in biomedical research” January 2019 in “DSpace@MIT (Massachusetts Institute of Technology)” Higher PHGDH levels cause unusual melanin buildup in hair follicles.
8 citations
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September 1981 in “Zentralblatt für Veterinärmedizin Reihe A” Biotin deficiency in pigs causes hair loss, skin issues, and weak claws.
22 citations
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September 2008 in “Brain & development” Biotin supplements increased biotin levels but did not significantly prevent hair loss in rats on valproic acid.
GPC1 is important for hair growth by helping blood vessels form around hair follicles.
September 2019 in “PubMed” The conclusion suggests using a science-based, multi-targeted treatment for hair loss instead of just biotin.
4 citations
,
July 2019 in “Clinical and experimental dermatology” Early diagnosis and biotin treatment are crucial for infants with biotinidase deficiency to prevent severe complications.