January 2026 in “RSC Advances” The hydrogel helps heal wounds without scars by releasing two drugs gradually.
May 2026 in “European Cells and Materials” The new delivery system improves Alzheimer's symptoms by releasing Huperzine A slowly and effectively.
25 citations
,
January 2010 in “International Journal of Pharmaceutics” Particle properties affect drug retention and release in minoxidil foams, with lipid nanoparticles having higher loading capacity.
February 2024 in “International Journal of Biological Macromolecules” The study created a new type of microsphere that effectively regrows hair.
47 citations
,
July 2014 in “European Journal of Pharmaceutics and Biopharmaceutics” Scientists created a gel with nanoparticles to deliver medicine to hair follicles effectively.
14 citations
,
November 2024 in “Pharmaceuticals” Spanlastic nano-vesicles improve famotidine's effectiveness and absorption.
March 2018 in “International Pharmacy Acta” New niosomal formulation effectively delivers aminexil through rat skin.
37 citations
,
May 2007 in “International Journal of Pharmaceutics” PPCM microspheres allow controlled finasteride release over 24 hours.
34 citations
,
April 2009 in “Skin Pharmacology and Physiology” Minoxidil affects cell growth in two ways: low doses increase growth, while high doses slow it down and can be toxic.
3 citations
,
May 2016 in “Behavioural Brain Research” Finasteride given to baby rats reduces dopamine release and increases alcohol consumption in adult males.
March 1998 in “Journal of dermatological science” Diphencyprone initially increases mouse hair growth, then slows it, possibly due to changes in specific protein levels.
355 citations
,
August 2013 in “Acta Biomaterialia” The nanofibers with two growth factors improved wound healing by supporting structure, preventing infection, and aiding tissue growth.
March 2023 in “International journal of pharmaceutical sciences review and research” The F2 Emulgel with Tridax procumbens extract showed good physical properties and antimicrobial effectiveness for wound healing.
27 citations
,
April 2008 in “Journal of Biological Chemistry” HMG-CoA reductase is crucial for skin wound healing by regulating keratinocyte growth and blood vessel formation.
284 citations
,
May 2002 in “Proceedings of the National Academy of Sciences” CRH promotes fat production in skin cells, affecting conditions like acne.
101 citations
,
October 2013 in “Journal of The Saudi Pharmaceutical Society” Minoxidil-loaded NLC gel shows potential for effective alopecia treatment.
5 citations
,
August 2025 in “Drug Delivery and Translational Research” Lipid-polymer hybrid nanoparticles show promise for skin treatments but need better formulation strategies.
4 citations
,
July 2025 in “International Journal of Nanomedicine” Nano-quercetin improves quercetin's effectiveness in treating diseases but faces challenges in safety and production.
July 2026 in “International Journal of Drug Delivery Technology” This review explores novel drug delivery systems (NDDS) for alopecia treatment, focusing on enhancing drug localization in the pilosebaceous unit to improve follicular retention and reduce systemic exposure and irritation. It discusses various delivery systems, including lipid-based carriers, polymeric nanoparticles, and vesicular systems, which show promise for improved follicular targeting and sustained release. The review emphasizes the potential of combining these systems with biologic therapies like exosomes for enhanced hair regeneration. However, it highlights the need for rigorous safety assessments, manufacturing standardization, and clinical evidence to ensure efficacy and patient compliance, as no single delivery system is universally optimal.
1057 citations
,
November 2011 in “Annals of Biomedical Engineering” Low-level Laser Therapy may help reduce inflammation, pain, and aid healing, but more research is needed to confirm its effectiveness and establish standard treatment guidelines.
520 citations
,
January 2017 in “AIMS biophysics” Photobiomodulation therapy using red and near-infrared light can reduce inflammation and aid in healing various conditions.
32 citations
,
December 2017 in “Journal of Drug Delivery Science and Technology” Minoxidil and caffeine in transfersomes improve hair growth treatment.
19 citations
,
October 2018 in “Medicine” Oriental herbal medicine with moxibustion may improve pregnancy rates and other symptoms in PCOS, but more high-quality research is needed.
The new microneedle system improves hair growth in alopecia treatment.
October 2022 in “Journal of Pharmaceutical Negative Results” Photobiomodulation therapy shows promise in treating various health conditions by using specific light wavelengths.
1 citations
,
August 2013 in “Springer eBooks” Birth control pills and anti-androgen medications help manage hair growth, acne, and hair loss in women with PCOS.
67 citations
,
January 2022 in “Theranostics” Advanced nanocarrier and microneedle drug delivery methods are more effective, safer, and less invasive for treating skin diseases.
9 citations
,
January 2021 in “BioMed research international” Human hair-derived particles can effectively carry and release the cancer drug Paclitaxel in a pH-sensitive manner, potentially targeting cancer cells while sparing healthy ones.
5 citations
,
February 2024 in “Frontiers in bioengineering and biotechnology” Electrospun scaffolds can improve healing in diabetic wounds.
4 citations
,
March 2020 in “Scientific Reports” Scientists created a colored thread-like material containing a common hair loss treatment, which slowly releases the treatment over time, potentially offering an effective, neat, and visually appealing solution for hair loss.