122 citations
,
June 2002 in “Genes & Development” Keratin 17 is crucial for early hair strength and cell survival.
82 citations
,
November 1985 in “Archives of Dermatology” The newborn's skin condition improved over time, leaving only lighter skin patches.
20 citations
,
August 2003 in “Clinical and Experimental Dermatology” A new genetic mutation in the hairless gene causes a rare hair loss disorder.
19 citations
,
November 1985 in “Archives of Dermatology” The newborn's skin blisters healed without scarring, leaving some light spots, and stopped forming after four months.
9 citations
,
July 2024 in “Internal Medicine Journal” Gender-affirming hormone therapy improves mental health and gender incongruence but requires careful management of cardiovascular and cancer risks.
6 citations
,
November 2014 in “The journal of investigative dermatology/Journal of investigative dermatology” Stephen Rothman made important discoveries in dermatology, including the use of PABA in sunscreens, but never profited from his work.
6 citations
,
March 2009 in “Annals of Saudi Medicine” Finasteride use during early pregnancy may cause limb deformities in babies.
1 citations
,
October 2022 in “Curēus” Diagnosing simple-virilizing congenital adrenal hyperplasia can be difficult and requires thorough testing and expert advice.
January 2026 in “JCEM Case Reports” Genetics may play a significant role in gender dysphoria.
October 2024 in “Journal of the Endocrine Society” Estrogen alone may effectively suppress testosterone in some transfeminine individuals.
October 2024 in “Journal of the Endocrine Society” Estrogen alone can lower testosterone in some transfeminine people.
September 2023 in “Journal of the American Academy of Dermatology” A rare benign scalp tumor in an infant requires surgical removal.
July 2018 in “Kidney international” Genetic testing for EGFR mutations is crucial in similar cases.
September 2016 in “European Journal of Pediatric Dermatology/PD. European journal of pediatric dermatology” Ulerythema ophryogenes causes hair thinning and inflammation, with limited treatment options.
March 2016 in “The Journal of Urology” The discovery of 5α-reductase deficiency in guevedoces led to the development of important urologic medications.
April 2012 in “Journal of evolution of medical and dental sciences” No effective treatment exists to stimulate hair growth in atrichia with papular lesions.
January 2006 in “International water power & dam construction” Nevus comedonicus can appear later in life and affect both eyelids.
December 2021 in “BMJ Open” Androgenetic alopecia in men aged 46 is not significantly linked to depression, anxiety, quality of life, self-esteem, or sexual symptoms.
169 citations
,
May 2006 in “Genes & Development” Keratin 17 is crucial for normal hair growth by regulating hair cycle transitions with TNFα.
166 citations
,
July 1999 in “American Journal Of Pathology” The hairless (hr) gene is essential for normal hair follicle function and its mutation leads to hair loss.
139 citations
,
August 2006 in “Molecular and Cellular Biology” Rac1 is vital for hair follicle health but not needed for skin maintenance.
84 citations
,
February 1981 in “Journal of Endocrinology” Epidermal growth factor slows hair and body growth in mice.
72 citations
,
January 1983 in “The Anatomical Record” Epidermal growth factor delays skin and hair development in mice.
71 citations
,
May 1996 in “Journal of Investigative Dermatology” Ornithine decarboxylase is crucial for hair growth regulation in mice.
63 citations
,
December 2010 in “Journal of Endocrinology” Reduced neurosteroids and growth issues can harm fetal brain development, especially in males.
53 citations
,
September 1999 in “The journal of cell biology/The Journal of cell biology” K16 can partially replace K14 but causes hair loss and skin issues.
51 citations
,
January 1997 in “PubMed” GABEB is a less severe skin condition caused by a gene mutation affecting collagen, leading to blisters and other symptoms.
46 citations
,
January 2010 in “The journal of investigative dermatology/Journal of investigative dermatology” Mice lacking Insig proteins had hair growth problems due to cholesterol buildup, but this was fixed by the drug simvastatin.
46 citations
,
May 2003 in “Mechanisms of Development” Increasing calcium sensing receptor speeds up skin and hair development in mice.
42 citations
,
September 2000 in “British Journal of Dermatology” Some children are born with unusually short, fine hair because their hair growth phase is short, but this often gets better by itself during puberty.