31 citations
,
January 2003 in “Dermatology” Steroidogenic isoenzymes may help improve treatments for common hair loss.
30 citations
,
March 2017 in “ACS biomaterials science & engineering” Hair follicles are valuable for regenerative medicine and wound healing.
30 citations
,
April 2013 in “Journal of Investigative Dermatology” Radiation mainly affects keratinocyte stem cells, not melanocyte stem cells, causing hair to gray.
30 citations
,
June 2012 in “Current Opinion in Endocrinology, Diabetes and Obesity” Nonclassic congenital adrenal hyperplasia is a genetic disorder causing hormone imbalances, affecting fertility and requiring personalized treatment.
26 citations
,
December 2016 in “Pharmacology & Therapeutics” New drugs for heart disease may be developed from molecules secreted by stem cells.
26 citations
,
April 1999 in “Dermatologic Clinics” The long-pulsed alexandrite laser is effective for hair reduction, particularly for light-skinned individuals with dark hair, but caution is needed for darker skin.
24 citations
,
May 2019 in “PLOS genetics” Mutations in the HEPHL1 gene cause abnormal hair and cognitive issues.
24 citations
,
October 2017 in “Biomolecules” Some growth factors, while important for normal body functions, can cause diseases when not regulated properly.
24 citations
,
December 2013 in “Sexual medicine reviews” Finasteride can cause sexual problems and depression in young men.
24 citations
,
April 2012 in “Developmental Biology” Dermal papillae cells, important for hair growth, come from multiple cell lines and can be formed by skin cells, regardless of their origin or hair cycle phase. These cells rarely divide, but their ability to shape tissue may contribute to their efficiency in inducing hair growth.
21 citations
,
July 2019 in “Cardiovascular Research” High levels of male hormones in pregnant mice cause heart enlargement and poor heart function in their female babies.
19 citations
,
August 2019 in “Expert Opinion on Therapeutic Targets” New treatments for hair loss may target specific pathways and generate new hair follicles.
18 citations
,
November 2020 in “Frontiers in Cell and Developmental Biology” Inflammation plays a key role in activating skin stem cells for hair growth and wound healing, but more research is needed to understand how it directs cell behavior.
18 citations
,
October 2014 in “Experimental Biology and Medicine” Eating vitamin A affects hair growth and health by changing cell signals in mice.
18 citations
,
March 2014 in “Current Pharmaceutical Biotechnology” Metformin helps regulate menstrual cycles, induce ovulation, and improve pregnancy outcomes in women with PCOS.
17 citations
,
September 2019 in “Journal of Cell Biology” Hair follicle regeneration may slow tumor growth.
17 citations
,
January 2014 in “Stem Cells Translational Medicine” Canine epidermal neural crest stem cells could be a promising treatment for spinal cord injuries in dogs.
17 citations
,
January 2006 in “Veterinary Dermatology” Topical melatonin and brushing did not affect hair regrowth in Siberian Huskies.
16 citations
,
December 2019 in “Journal of Cellular and Molecular Medicine” Sonicated platelet-rich plasma boosts hair growth by activating stem cells.
16 citations
,
September 2008 in “Dermatologic Therapy” CAH is a genetic disorder affecting cortisol production and causing hormonal imbalances, with treatment and diagnosis varying by form and symptoms.
16 citations
,
December 2006 in “Expert Review of Dermatology” Hair follicles are essential for skin health, aiding in hair growth, wound healing, and immune function.
15 citations
,
January 2002 in “Gynecological endocrinology” Hormones affect skin aging and fat distribution, and treatments can help, but only minoxidil is proven for female hair loss.
14 citations
,
January 2018 in “Scientific reports” Bioluminescence imaging can track hair follicle cells and help study hair regrowth.
14 citations
,
December 2003 in “BJUI” Finasteride can treat prostatic haematuria, but its use is controversial.
11 citations
,
December 2014 in “The American journal of pathology” A gene deletion in mice causes weak protein, immune issues, hair loss, airway problems, and wasting disease.
10 citations
,
May 2024 in “npj Regenerative Medicine” Umbilical cord cells may help delay skin aging.
10 citations
,
November 2019 in “Cold Spring Harbor Perspectives in Biology” Stem cells are more dynamic and adaptable than previously believed.
10 citations
,
September 2015 in “PLoS ONE” New mutations in the VDR gene cause vitamin D-resistant rickets without hair loss.
10 citations
,
December 2011 in “Cell Transplantation” Researchers successfully grew human hair follicle cells that could potentially lead to new hair loss treatments.
10 citations
,
November 2010 in “Pigment Cell & Melanoma Research” Only skin melanocytes, not other types, can color hair in mice.