11 citations
,
November 2009 in “Journal of steroid biochemistry and molecular biology/The Journal of steroid biochemistry and molecular biology” Bolandiol, a synthetic steroid, builds muscle and bone without greatly affecting sex glands, and works differently from other hormones.
11 citations
,
August 2007 in “Bioorganic & Medicinal Chemistry Letters” Scientists made a chemical (compound 4e) that can be applied on skin to reduce oil production, which can help with acne, but it might cause skin sensitivity to light.
11 citations
,
January 1990 in “Cell and Tissue Research” Minoxidil does not specifically target any hair follicle cells.
10 citations
,
April 2023 in “JAAD Case Reports” Topical clascoterone may help treat hidradenitis suppurativa.
10 citations
,
October 2018 in “Journal of molecular and cellular cardiology/Journal of Molecular and Cellular Cardiology” The gene NM_026333 slows down aging by affecting the NCX1 pathway and could be targeted for anti-aging treatments.
10 citations
,
November 2009 in “Pigment cell & melanoma research” The document concludes that MGRN1 affects mouse fur color by interfering with a receptor's signaling, but its full role in the body is still unknown.
10 citations
,
November 1984 in “Journal of Colloid and Interface Science” The study found that the Marangoni effect causes the uneven wetting of surfactant-coated hair due to the surfactant moving into the water.
10 citations
,
January 1980 in “Ultrastructural pathology” Green hair has high copper levels due to contaminated water and damaged hair cuticles.
9 citations
,
April 2021 in “Expert opinion on pharmacotherapy” Clascoterone is a new, effective, and safe acne treatment without systemic side effects.
9 citations
,
June 1999 in “Acta Obstetricia Et Gynecologica Scandinavica” Oral contraceptives are effective for treating hyperandrogenism, while ovarian electrocautery is better for women with infertility.
9 citations
,
December 1996 in “Cell Biology and Toxicology” Hair follicle cells produce VEGF, which can promote blood vessel cell growth and movement.
9 citations
,
March 1991 in “Endocrinology” Using two drugs together, Flutamide and 4-MA, is more effective for blocking male hormones than using each one alone.
The document concluded that certain compounds might strongly bind to and potentially inhibit a key SARS-CoV-2 protein, but further testing is needed.
8 citations
,
March 2019 in “Journal of Biomedical Materials Research Part A” Sulfated hyaluronan in collagen helps hair follicle cells grow and develop better for skin grafts.
8 citations
,
September 2017 in “Journal of Investigative Dermatology” CXXC5 is a protein that prevents hair growth and could be a target for hair loss treatment.
8 citations
,
December 2016 in “Hormone Research in Paediatrics” Tunisian children with hereditary vitamin D-resistant rickets showed improvement with calcium treatment, and new genetic mutations were identified.
8 citations
,
October 2013 in “Chemistry Central Journal” Metabolite 7 is a strong inhibitor for Alzheimer's disease management.
8 citations
,
April 2013 in “Advances in Wound Care” α3β1 integrin is essential for skin stability and proper wound healing.
8 citations
,
June 2004 in “Journal of Investigative Dermatology” Certain peptides can prevent hair loss in young rats caused by a cancer drug.
7 citations
,
March 2023 in “Arabian Journal of Chemistry” Cepharanthine may help treat COVID-19 by targeting multiple pathways.
7 citations
,
January 2017 in “Biological & Pharmaceutical Bulletin” Certain compounds from Panax ginseng can block proteins that affect hair growth, potentially helping treat hair loss.
7 citations
,
January 2013 in “Journal of Investigative Dermatology” Vitamin A may influence hair loss conditions like alopecia, but more research is needed to understand how.
7 citations
,
March 2011 in “Expert Opinion on Drug Safety” Exemestane is effective and safe for treating certain breast cancers, with mild side effects, but needs more research on long-term effects.
7 citations
,
October 2010 in “Medical Hypotheses” Alopecia areata may involve stress-related changes affecting hormone receptors, leading to reduced cortisol production.
7 citations
,
November 2007 in “Differentiation” The NF-κB effector p65/RelA activates hair keratin genes, aiding hair formation.
7 citations
,
December 1971 in “Calcified Tissue Research” Hair follicles in injured skin can quickly accumulate minerals, especially calcium and phosphorus.
6 citations
,
March 2023 in “Frontiers in Cellular and Infection Microbiology” Golvatinib shows promise as a treatment for Omicron in elderly patients.
6 citations
,
June 2020 in “Journal of Drugs in Dermatology” PRP can help regrow hair in people with alopecia.
6 citations
,
February 2020 in “Journal of Natural Products” A new compound from a sponge strongly inhibits an enzyme linked to male-pattern hair loss without being toxic at low levels.
6 citations
,
November 2004 in “Bioorganic & Medicinal Chemistry Letters” Scientists created iodinated arylhydantoins and arylthiohydantoins that could potentially be used for imaging prostate cancer. Some versions with specific side-chains showed high potential for this use.