94 citations
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May 2011 in “BJCP. British journal of clinical pharmacology/British journal of clinical pharmacology” Hair follicles greatly increase caffeine absorption through the skin shortly after it's applied.
91 citations
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November 2007 in “Archives of Dermatology” Smoking linked to hair loss in Asian men.
86 citations
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September 1977 in “BMJ” Minoxidil effectively controls blood pressure in severe cases, but has serious side effects and causes hair growth in women.
66 citations
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June 2013 in “Journal of Dermatological Treatment” Finasteride and dutasteride effectively treat hair loss, but may cause side effects like sexual dysfunction and depression.
65 citations
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October 2008 in “Journal of Neuroendocrinology”
64 citations
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March 2006 in “Food Chemistry” The triterpenoids from Ganoderma lucidum can block testosterone effects and may help treat enlarged prostate.
60 citations
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September 2016 in “Dermatologic Surgery” PRP treatment may stimulate hair growth by promoting blood vessel formation, increasing growth factors, and preventing cell death.
60 citations
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January 1989 in “Toxicologic Pathology” Using minoxidil on dogs can cause serious cardiovascular damage, including arterial injury and hemorrhagic lesions.
55 citations
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October 2019 in “Dermatology and therapy” Drugs targeting the JAK/STAT pathway can improve atopic dermatitis but vary in effectiveness for vitiligo and alopecia areata, with generally mild safety concerns.
51 citations
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October 2002 in “European journal of endocrinology” Low-dose finasteride effectively treats hirsutism, is safe, and cost-effective.
49 citations
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June 1998 in “Journal of Endocrinological Investigation” Cyproterone acetate plus ethinyl estradiol is generally more effective in treating hirsutism, but consider side effects and patient characteristics.
47 citations
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January 2001 in “Journal of Investigative Dermatology” High testosterone to epitestosterone ratio in hair could predict male-pattern baldness.
47 citations
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November 1982 in “Journal of Cardiovascular Pharmacology” Nitrendipine and nifedipine effectively block muscle contractions, while papaverine relaxes them and minoxidil needs high amounts to work.
45 citations
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July 2009 in “Journal of Investigative Dermatology” The S100A4 protein is more common in psoriatic skin and could be a target for treating psoriasis.
43 citations
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January 1977 in “Toxicology and Applied Pharmacology” Minoxidil is mostly safe, but high doses can cause electrolyte imbalances and heart issues in dogs.
42 citations
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April 2021 in “Journal of clinical pharmacology” Baricitinib helps treat several diseases, including COVID-19, but has side effects and needs careful monitoring.
39 citations
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January 2019 in “Journal of Dermatological Treatment” Ketoconazole cream is effective for skin conditions like seborrheic dermatitis and may help with hair loss and other skin issues, with generally mild side effects.
39 citations
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August 2004 in “International journal of gynaecology and obstetrics” Finasteride and CPA-EE2 equally reduce hirsutism, but affect hormone levels differently.
38 citations
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January 2001 in “Neuroepidemiology” The current system can't fully test all combination treatments, so alternative methods and regulatory flexibility are needed.
36 citations
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March 2014 in “Biomaterials” A new skin-whitening agent using a peptide from wheat is safe and effective at reducing skin pigmentation.
35 citations
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January 2018 in “Skin pharmacology and physiology” Nanoemulsion creams with certain enhancers can greatly increase caffeine delivery through skin.
35 citations
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December 1979 in “Naunyn-schmiedebergs Archives of Pharmacology” These drugs raise prostaglandin-like material in dog blood, possibly causing blood vessel widening.
34 citations
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November 2013 in “Breast Cancer Research and Treatment” Aromatase inhibitor therapy for breast cancer increases the risk of hair loss and thinning.
34 citations
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July 2011 in “International journal of pharmaceutics” Ion-paired risedronate significantly increases skin penetration without irritation compared to risedronate alone.
34 citations
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January 1977 in “American Journal of Cardiology”
32 citations
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January 2005 in “Advances in Biochemical Engineering / Biotechnology” Fetal wounds heal without scarring because of different biological factors, which could help improve adult wound healing.
29 citations
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September 2017 in “Oncology and therapy” The document provides advice on how to recognize and treat skin-related side effects of cancer drugs known as EGFR inhibitors.
29 citations
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September 2004 in “Fertility and Sterility” Intermittent low-dose finasteride works as well as daily use for treating excessive hair growth in women.
27 citations
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August 2018 in “Frontiers in Plant Science” High levels of auxin increase root hair growth by activating RSL2 and producing ROS, while high phosphate levels hinder growth by repressing RSL2.
27 citations
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February 2014 in “Planta Medica” Scutellaria baicalensis extract and baicalin may help prevent hair loss.