Botulinum toxin type A reduces itch and inflammation from histamine and may help treat certain skin conditions and hair loss.
This study explored the role of the PGI2 pathway in diabetic foot ulcers (DFUs) using diabetic mouse models, a three-dimensional cellular model, and clinical studies. The research aimed to understand the alterations in the PGI2 pathway, which is crucial for vascular homeostasis and tissue repair. The study employed three techniques: in vivo skin microvascular reactivity assays, direct activation of PGI2 receptors, and analysis of gene and protein expression. The findings indicated changes in the PGI2 pathway in diabetic mice, particularly in gene and protein expression, but did not show dysfunction in the PGI2-dependent vasomotor effect. The study suggested that targeting the PGI2 pathway could be a potential therapeutic approach for DFUs.
19 citations
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March 1990 in “Journal of Cardiovascular Pharmacology” Minoxidil affects rat fluid dynamics, altering pressure and circulation, improving blood flow and hair growth.
July 2023 in “Clinical, cosmetic and investigational dermatology” Reflectance confocal microscopy helped tell periorificial dermatitis apart from similar skin conditions.
15 citations
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July 1991 in “International Journal of Dermatology” Laser Doppler velocimetry is a valuable noninvasive tool for skin blood flow research in dermatology.
April 2010 in “The Journal of Urology” The research found that androgens help control blood flow in the rat prostate through a specific binding site.
1 citations
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April 2017 in “Journal of Investigative Dermatology” D-OCT shows increased blood vessel growth in response to tissue damage in Frontal Fibrosing Alopecia and is useful for diagnosis and monitoring.
5 citations
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June 2024 in “Pharmacological Research” FOL-026 peptide may help hair growth and cardiovascular health by improving blood flow and cell functions.
1 citations
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September 2021 in “Skin appendage disorders” Botulinum toxin injections can help treat common hair loss in men, but more research is needed to confirm this and understand how it works.
April 2023 in “Journal of Investigative Dermatology” Sunlight simulation causes skin inflammation, with different skin types reacting at different levels of exposure.
50 citations
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November 2010 in “Plastic and Reconstructive Surgery” Botox increased hair count in men with baldness and might work by improving scalp blood flow.
1 citations
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November 2023 in “Biomedicines” Menopause can cause hair thinning and texture changes due to hormonal and metabolic shifts.
November 2008 in “Medical Hypotheses” The conclusion suggests a new treatment for infantile hemangiomas and a potential target for hair loss treatment.
Low-level light therapy may reduce hair loss and improve hair quality but it's unclear who benefits most.
September 2025 in “Journal of Zhejiang University (Medical Sciences)” Peripheral nerves are essential for skin wound healing and future treatments could improve by focusing on nerve and blood vessel regeneration.
527 citations
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December 2011 in “Proceedings of the National Academy of Sciences” Dextran hydrogels improve burn wound healing and skin regeneration.
December 2011 in “The Diabetes Educator” The Blood Glucose Management Service improved patient safety and outcomes in managing blood sugar in hospitalized patients.
5 citations
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July 2020 in “Experimental Physiology” Traditional methods may not fully capture how the brain and breathing systems respond to carbon dioxide changes.
November 2023 in “Journal of animal science/Journal of animal science ... and ASAS reference compendium” SLICK cattle have better heat tolerance due to specific gene expression and pathway differences.
March 2021 in “Postepy Dermatologii I Alergologii” Minoxidil works equally well for hair growth regardless of scalp blood flow.
Women with PCOS have different body composition and some metabolic differences compared to healthy women.
183 citations
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January 1987 in “British Journal of Anaesthesia” Opioid painkillers can cause many side effects, including breathing problems and addiction, but are generally considered safe when used properly.
67 citations
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July 2016 in “Reviews in Endocrine and Metabolic Disorders” Stress can worsen skin conditions by affecting hormone levels and immune response.
August 2016 in “PolyPublie (École Polytechnique de Montréal)” Doxorubicin causes heart damage, so early detection and monitoring are important during chemotherapy.
10 citations
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October 2014 in “Plastic & Reconstructive Surgery Global Open” Botulinum toxin type A injections improved hair growth and scalp health in a woman with radiation-induced hair loss.
September 2025 in “Chinese Journal of Plastic and Reconstructive Surgery” Botulinum toxin may help treat hair loss but needs more research for effectiveness and cost concerns.
13 citations
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September 2022 in “Journal of Animal Behaviour and Biometeorology” Elephants use their skin, ears, and behavior to cool down, but climate change makes it harder for them.
February 2024 in “Cosmoderma” Low-dose oral minoxidil can help treat male and female pattern hair loss, especially in those who can't use topical treatments or have heart health issues.
137 citations
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May 1984 in “Journal of Investigative Dermatology” Minoxidil increases blood flow in balding scalps, possibly reversing hair loss.
25 citations
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November 1987 in “British Journal of Dermatology” Minoxidil didn't increase scalp blood flow for hair growth, but hexyl nicotinate did.