25 citations
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December 2017 in “The Journal of Clinical Endocrinology & Metabolism” Birth control pills combined with bicalutamide are more effective at reducing excessive hair growth in women with PCOS than birth control pills alone.
13 citations
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January 2015 in “Steroids” The study created a model to help design new inhibitors for steroidal 5α-reductase enzymes.
1 citations
,
December 2005 in “The Journal of Urology” Combination therapy for BPH is more effective in certain men but may not be cost-effective due to minimal impact and potential side effects.
January 2025 in “Thieme Medical and Scientific Publishers Private Limited eBooks” 1 citations
,
November 2021 in “British Journal of Clinical Pharmacology” Saw palmetto may cause erectile dysfunction and needs better safety monitoring.
January 2012 in “Земский врач” Finasteride helps improve treatment for benign prostatic hyperplasia.
14 citations
,
February 2011 in “Drug Metabolism and Disposition” Ketoconazole increases finasteride's effectiveness and lifespan in the body.
December 2013 in “The Journal of Urology” 
42 citations
,
May 2003 in “Mini-reviews in Medicinal Chemistry” New steroidal compounds could be effective for treating conditions related to 5α-reductase enzyme activity.
August 2016 in “Journal of Investigative Dermatology” August 2018 in “Daehan binyogi jong-yang haksulji” Taking sildenafil and finasteride together is safe and improves urinary and sexual symptoms in BPH patients.
13 citations
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November 2019 in “Scientific reports” Certain drugs change freshwater snail shells to a "banana" shape.
408 citations
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May 2004 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” Dutasteride more effectively lowers DHT levels in men with enlarged prostates than finasteride.
May 2022 in “Endocrine Abstracts” Finasteride may cause sexual dysfunction by reducing epinephrine levels.
20 citations
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December 2015 in “Der Urologe” Combining medications is more effective for treating benign prostatic syndrome symptoms.
January 2025 in “JAAD International” Bicalutamide added no extra benefit over minoxidil alone for female-pattern hair loss.
38 citations
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January 2005 in “PubMed” Dutasteride effectively treats enlarged prostate with manageable side effects.
September 2025 in “Arthritis Research & Therapy” The study explores the use of the melanocortin compound BMS-470539 to target fibrosis by inducing a 'senescence-like' state in human dermal fibroblasts, particularly from systemic sclerosis patients. This state is characterized by proliferation arrest and reduced pro-inflammatory activity, leading to the downregulation of fibrosis markers. In vitro and in vivo models, including a bleomycin-induced skin fibrosis murine model, demonstrated that BMS-470539 effectively reduced skin thickness and fibrosis markers without causing additional fibrosis when administered intradermally. The findings suggest a promising therapeutic strategy to manage fibrosis and potentially other diseases with shared pathogenic mechanisms, such as arthritis.
53 citations
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June 1993 in “Proceedings of the National Academy of Sciences of the United States of America” LY191704 is a compound that effectively blocks a specific enzyme involved in hormone conversion and could help treat enlarged prostate and hair loss.
13 citations
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January 2017 in “Chemical & Pharmaceutical Bulletin” Certain compounds, especially those with a propionic substituent, could potentially be new treatments for hair loss and similar disorders.
2 citations
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August 2016 in “Experimental Dermatology” Finasteride treats baldness but may cause lasting sexual side effects.
13 citations
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December 2011 in “Korean Journal of Food Science and Technology” Black soybean extract helps promote hair growth and could prevent hair loss.
May 2015 in “Journal of The American Academy of Dermatology” Finasteride for hair loss in young men increases the risk of sexual dysfunction.
32 citations
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September 2010 in “Stress” Neurosteroids help protect fetal brains from asphyxia damage.
December 1998 in “Acta Crystallographica Section C-crystal Structure Communications” A new compound with strong antiandrogenic effects was found, potentially useful for treating conditions like acne and prostate cancer.
February 2013 in “Journal of The American Academy of Dermatology” Finasteride solution helps treat hair loss.
June 2018 in “The Journal of Sexual Medicine” Finasteride helps female-pattern hair loss.
October 2010 in “Journal of Men's Health” Some patients may experience lasting sexual dysfunction, depression, and other side effects from 5α-reductase inhibitor therapy.
2 citations
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April 2024 in “Urology Annals” Taking dutasteride every other day works as well as daily and better preserves sexual function.
28 citations
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August 2013 in “Hypertension” Potassium channel openers help form elastic fibers in arteries and can treat elastin deficiency and hypertension.