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July 2019 in “Journal of Biological Inorganic Chemistry” Finasteride helps prevent kidney stones, but side effects need more research.
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January 2015 in “Analytical Methods” Method accurately measures finasteride in tablets using finasteride-BSA interaction.
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January 2020 in “Biomaterials Science” Created microspheres show potential for safe and effective use in prostate artery embolization.
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January 2011 in “Urologia Internationalis” Finasteride may help prevent chronic bacterial prostatitis, with better results when combined with antibiotics.
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September 2018 in “Dermatologic Therapy” Finasteride effectively stops hair loss in most patients, but concerns about rare sexual side effects exist.
13 citations
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June 2018 in “Current Urology Reports” Hair loss drugs may cause sexual issues and infertility in men.
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August 2013 in “Journal of pharmaceutical sciences” Researchers created a skin patch that delivers two drugs for treating enlarged prostate, which may improve patient use and dosage control.
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November 2012 in “PubMed” 5α-reductase inhibitors may worsen sexual drive and spontaneous erections but don't worsen existing erectile or ejaculatory problems.
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August 2007 in “Bioorganic & medicinal chemistry letters” A new compound effectively inhibits human 5α-reductase 1.
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November 2006 in “E-journal of Chemistry” Found accurate way to measure finasteride in tablets.
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January 2005 in “Chemical and Pharmaceutical Bulletin” Smaller substituents at C-17 enhance the inhibitory activity of progesterone derivatives on 5alpha-reductase.
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August 1995 in “The Journal of Steroid Biochemistry and Molecular Biology” The activity of a specific rat enzyme in the prostate and epididymis is highly dependent on the acidity level.
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December 2012 in “Current Drug Targets” The Androgen Receptor could be a target for treating diseases like cancer, but more research is needed to confirm the effectiveness of potential treatments.
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June 2001 in “Bioorganic & Medicinal Chemistry” Changing the C-ring structure in certain compounds can make them better at blocking a specific human enzyme.
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January 1998 in “Endocrine journal” Saw palmetto extract can block the enzyme that converts testosterone in pig prostate cells.
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April 2018 in “Journal of Dermatology” Dutasteride safely treats hair loss without harming sexual function.
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September 2008 in “European Journal of Drug Metabolism and Pharmacokinetics” Finasteride helps reduce pain and inflammation in animals.
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November 2001 in “Journal of Chromatography B: Biomedical Sciences and Applications” Finasteride and analogues separated using LC-MS-MS technique.
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December 2014 in “Journal of Pharmaceutical and Biomedical Analysis” Finasteride's polymorphic form affects capsule quality and drug effect, requiring strict control.
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June 2010 in “Expert Opinion on Drug Metabolism & Toxicology” Finasteride reduces prostate cancer risk but may increase high-grade cancer chances.
9 citations
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January 2018 in “American Journal of Men's Health” Finasteride use can cause lasting negative effects like sexual dysfunction, depression, anxiety, and cognitive issues.
9 citations
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September 2010 in “Dermatologic Therapy” Finasteride for hair loss is safe and does not increase the risk of high-grade prostate cancer.
8 citations
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July 2018 in “Analytical sciences” Using 5-butylpicolinate esters improves the sensitivity and reliability of detecting testosterone and dihydrotestosterone in saliva.
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January 2018 in “PubMed” Smaller finasteride particles increase effectiveness in treating hair loss.
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May 2017 in “Current traditional medicine” Stinging nettle has compounds that help with joint pain, arthritis, and prostate issues.
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February 2007 in “Journal of The American Academy of Dermatology” Higher serum ferritin levels than currently used might be needed to rule out iron deficiency in women with hair loss.
7 citations
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June 2020 in “Translational Andrology and Urology” Finasteride for hair loss may cause lasting sexual, genitourinary, mental, and anti-androgenic side effects in young men.
7 citations
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February 2019 in “Journal of pharmacological sciences” Bazhengsan reduces inflammation and tissue growth in chronic prostatitis.
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March 2015 in “The American Journal of the Medical Sciences” Finasteride helps reduce blood vessel growth in diabetic rat kidneys.
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January 2018 in “Pharmacoepidemiology and Drug Safety” Starting 5-alpha reductase inhibitors does not significantly increase the risk of rhabdomyolysis in older men, but is linked to a higher risk of muscle conditions.