research Medical consequences of long-term anabolic-androgenic Steroids (AASs) abuses in athletes
Long-term steroid abuse in athletes causes serious health risks, outweighing any benefits.
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research Gender-Affirming Hormone Therapy for Transgender Men
Testosterone therapy seems safe and effective for transgender men with proper care, but more long-term research is needed.
research Curtailing PCOS
Lifestyle changes are the main treatment for PCOS, which is a complex condition requiring early management to reduce its health impacts.
research Polycystic Ovarian Syndrome: Long-Term Health Consequences
Women with PCOS have a higher risk of diabetes, heart problems, certain cancers, and mental health issues, but early treatment can help manage these risks.
research Chapter 6. Darwinian Health and Other Contradictions
The document concludes that understanding health requires considering evolutionary perspectives on reproductive fitness, and recognizing the complexity of factors like diet, testosterone, and sexual orientation.
research Adrenal Cortex Tumors and Hyperplasias
Most adrenal cortex tumors are benign and non-secreting, but proper diagnosis and treatment are important due to the rare possibility of cancer.
research Lignans and Neolignans: Plant secondary metabolites as a reservoir of biologically active substances
Lignans and neolignans from plants may help protect against various health issues, including cancer and heart disease.
research Health and fertility in World Health Organization group 2 anovulatory women
Women with PCOS may take longer to get pregnant but can have a normal family size, and should manage their overall health to reduce long-term health risks.
research Managing Polycystic Ovary Syndrome: A Cognitive Behavioral Strategy
Cognitive behavioral strategies help women with PCOS make lifestyle changes to improve their health.
research Androgen antagonists in androgen target tissues
Antiandrogens have important biological effects, but more research is needed to understand them fully and compare their effectiveness and side effects to other treatments.
research Expression and function of nuclear receptor co-activator 4: evidence of a potential role independent of co-activator activity
NcoA4 may have roles beyond helping control gene activity, possibly affecting cell behavior and stability.
research Integrated safety analysis of baricitinib in adults with severe alopecia areata from two randomized clinical trials
Baricitinib for severe alopecia areata is generally safe, with common side effects like infections and acne, and low rates of serious complications.
research Non-canonical dimerization of the androgen receptor and other nuclear receptors: implications for human disease
Mutations in certain receptors can cause diseases and offer new treatment options.
research Genome-wide association study of skin complex diseases
Genetic variants linked to ten skin diseases were found, showing both immune and non-immune factors play a role.
research Lichen Planopilaris in Women
Women with lichen planopilaris often have thyroid disease, depression, anxiety, and may respond to treatment with slowed disease progression.
![Synthesis, Biological Evaluation, and Molecular Docking of 4-Amino-2H-benzo[h]chromen-2-one Analogs Containing the Piperazine Moiety](/images/research/2ecf4eed-7dbe-4f1a-83db-739625546cdd/small/31808.jpg)
research Synthesis, biological evaluation and molecular docking of 4-Amino-2H-benzo[h]chromen-2-one (ABO) analogs containing the piperazine moiety
Analog 23 is a promising compound for prostate cancer treatment.
research Dermatologic Care of the Transplant Patient
Transplant patients on immunosuppressive medications have a higher risk of skin cancer, and managing this involves balancing medication with cancer risk.
research Polycystic Ovary Syndrome: A Comprehensive Review of Its Clinical Presentation, Comorbidities, Long-Term Complications and Management
PCOS is a common disorder in women causing symptoms like irregular periods and weight gain, with management possible through lifestyle changes and medication.
research Irregular Menstruation, Acne, Hirsutism, and the Possibility with PCOS
Women with irregular periods should be checked for PCOS and treated early to prevent complications, with birth control pills helping to manage symptoms.
research Stem Cells in the Skin
Skin stem cells are crucial for maintaining and repairing skin, with potential for treating skin disorders and improving wound healing.
research History and physical examination of polycystic ovary syndrome: Detecting too much or too little
The document concludes that careful history and physical exams are crucial for accurately diagnosing polycystic ovary syndrome and distinguishing it from other similar conditions.
research Clinical Impact of Molecular Diagnostics in Endocrinology
Molecular diagnostics help identify genetic defects causing endocrine diseases, improving diagnosis and treatment options.
research Gonads
The document concludes that accurate diagnosis of male and female gonadal disorders is crucial for effective treatment and better patient outcomes.
research 5α-Reduced glucocorticoids: a story of natural selection
Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.
research Recent Advances in the Chemistry and Pharmacological Activity of New Steroidal Antiandrogens and 5α-Reductase Inhibitors
New compounds show promise for treating hair loss, enlarged prostate, and prostate cancer, with some being more effective and having different side effects than current treatments.
research 5-Alpha-Reductase Inhibitors and Combination Therapy
Finasteride and dutasteride are effective for long-term treatment of enlarged prostates but have sexual side effects and a risk of high-grade prostate cancer.
research Recent Advances in Drug Design and Drug Discovery for Androgen- Dependent Diseases
New treatments for prostate cancer and BPH show promise, including novel compounds that target hormone synthesis and response.
research Combined analysis of two multicenter studies of finasteride 5 mg in the treatment of symptomatic benign prostatic hyperplasia
Finasteride 5 mg effectively reduces urinary symptoms and PSA levels in men with enlarged prostates, with few sexual side effects.
research An Update on Alopecia and its Association With Thyroid Autoimmune Diseases
People with alopecia have a higher risk of thyroid cancer.
research Medicinal plants use for home remedies in Sri Lanka: A Review
The document concludes that in Sri Lanka, 25 common plants are traditionally used as home remedies for various health issues due to their medicinal properties.