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5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.

Keratin 15 is not a reliable sole marker for identifying epidermal stem cells because it's found in various cell types.

Epidermal stem cells could lead to new treatments for skin and hair disorders.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

Targeting ACE2 and TMPRSS2 may help prevent or treat COVID-19 in cancer patients.

Cyproterone acetate treatment is safe and causes mild feminization, which increases with added estrogen.

Finasteride reduces prostate cancer risk but may affect ejaculatory volume and requires careful consideration for young men.

NGAL may help maintain skin balance and is linked to skin disorders and cancers.

New compounds show promise for treating hair loss, enlarged prostate, and prostate cancer, with some being more effective and having different side effects than current treatments.

Children with HIV often have skin problems that can indicate the severity of their immune system damage.

Androgens and SARMs play a role in body mass, frailty, skin health, and hair growth, and are used in treating prostate cancer, acne, and hair loss, with potential for new uses and improved versions in the future.

Finasteride and dutasteride are effective for long-term treatment of enlarged prostates but have sexual side effects and a risk of high-grade prostate cancer.

5α-reductase inhibitors may worsen sexual drive and spontaneous erections but don't worsen existing erectile or ejaculatory problems.

New treatments for prostate cancer and BPH show promise, including novel compounds that target hormone synthesis and response.

The document concludes that managing PCOS involves treating symptoms, regulating periods, and reducing health risks, with specific medications for fertility and metabolic issues.

Skin health and diseases are closely linked to metabolic processes.

A new mutation linked to partial Androgen Insensitivity Syndrome and prostate cancer was found in a patient unhappy with their female gender assignment.

The document concludes that the skin is a complex organ providing protection, sensation, and healing, with challenges in treating conditions like itchiness.

A rare ovarian tumor caused early puberty in a 3-year-old girl.

Actinic keratosis is a sun-induced skin condition that can potentially turn into skin cancer and requires treatment to prevent malignancy.

People with alopecia have a higher risk of thyroid cancer.

The document concludes that in Sri Lanka, 25 common plants are traditionally used as home remedies for various health issues due to their medicinal properties.

Trichilemmal carcinoma shares genetic traits with other skin cancers, suggesting similar treatment options.

Trichilemmal carcinoma shares genetic traits with other skin cancers, suggesting similar treatment options.

Hidradenitis Suppurativa is likely an autoinflammatory disease, and better understanding its causes could improve treatments.

Testosterone replacement therapy improves libido, mood, muscle strength, and bone density in men with Testosterone Deficiency Syndrome.

Finasteride's effects on prostate cancer are not clear from this text.

Finasteride may help some women with hair loss, but better options exist.

Hirsutism is common body hair growth due to genetics and hormones, and while not a disease, it can be distressing; virilisation includes hirsutism with other male traits and needs medical attention.

Severe acne in a young girl may indicate underlying hormonal issues.