research Gas Chromatography Tandem Mass Spectrometry for Biomarkers of Alcohol Abuse in Human Hair
A new method quickly detects alcohol use from hair in under an hour.
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510-540 / 1000+ resultsresearch An Innovative Reverse-Phase High-Performance Liquid Chromatography Technique For Measuring Finasteride And Tadalafil In Raw Materials And Pharmaceutical Products With Stability Indication
research Detection of testosterone propionate administration in horse hair samples
Hair analysis can detect testosterone in horses after drug administration.
research Theoretical evaluation of interaction of some dibenzo derivatives on both androgen receptor and 5α-reductase enzyme
Certain Dibenzo derivatives may help treat prostate cancer.
research Determination of some sex hormones in health supplements by liquid chromatography with tandem mass spectrometry
The method detected sex hormones in some health supplements, with one containing banned testosterone.
research Analysis of accumulation and acute phytotoxic reactions of Ocimum basilicum to lead contamination in the initial phases of plant development
Lead contamination harms basil roots despite some protection from seed exudate.
research Quantitative analysis of finasteride tablets dissolution content with non-isotopically labeled internal standard by paper spray ionization mass spectrometry
PSI-MS quickly and accurately measures finasteride in tablets, helping with quality control.
research Functional characterization of OR51B5 and OR1G1 in human lung epithelial cells as potential drug targets for non-type 2 lung diseases
Blocking certain receptors in the lungs might help treat a specific type of asthma.
research Generation of comparative pharmacophoric model for steroidal 5α-reductase I and II inhibitors: A 3D-QSAR study on 6-azasteroids
The study created a model to help design new inhibitors for steroidal 5α-reductase enzymes.
research Distinct Conditions Support a Novel Classification for Bradykinin-Mediated Angio-Oedema
The conclusion suggests a new way to classify bradykinin-mediated angio-oedema based on different causes and its possible link with urticaria, which could improve diagnosis and treatment.
research Synthesis and Evaluation of 2‘-Substituted 4-(4‘-Carboxy- or 4‘-carboxymethylbenzylidene)-N-acylpiperidines: Highly Potent and in Vivo Active Steroid 5α-Reductase Type 2 Inhibitors
Compounds 15, 20, and 25 are strong inhibitors of human steroid 5α-reductase type 2.
research Evaluation of Biological Activity Exerted by an Aza-bicyclocarboxylic acid Derivative using Anischemia-Reperfusion Injury Model
Compound 3 protects the heart from damage by activating A1-adenosine receptors.
research Adhesion Failure of External Hair Cuticles Caused by Prussian Blue: Possible Electrochemical Roles of Sulfur and Cystine
Prussian Blue causes hair cuticles to detach, weakening the hair.
research SIMULTANEOUS DETERMINATION OF FINASTERIDE AND TAMSULOSIN IN COMBINED DOSAGE FORM BY USING RP-HPLC METHOD
Method accurately measures finasteride and tamsulosin in combined drug form.
research Fiber-Safe Extraction of Red Mordant Dyes from Hair Fibers
A new method extracts red dyes from wool without damaging it, although it slightly weakens the wool.
research In Silico Screening of DrugBank Compounds as Potential Inhibitors for Human Steroid 5α-Reductase 2 for Androgen-Related Diseases
Stiripentol shows promise as a potential treatment for androgen-related diseases but needs more testing.
research Activity Test of Combination of Binahong Leaf Extract (Anredera Cordifolia) and Lemongrass Extract (Cymbopogon citratus) as Antifungal Againt Pityrosporum ovale
The combination of binahong leaf and lemongrass extracts effectively fights dandruff-causing fungus.
research Transcriptomic profiling of Arabidopsis Thaliana responses to Stutzerimonas stutzeri, chlorella vulgaris, and mixed consortium inoculation under salt stress
research A rapid method for obtaining finasteride, a 5α-reductase inhibitor, from commercial tablets
Quickly get finasteride from tablets using easy methods.
research Potassium channel openers: pharmacological and clinical aspects
Potassium channel openers could help treat cardiovascular diseases and asthma but require better targeting to specific tissues for effective use.
research Mitochondrial Complex I Activity Suppresses Inflammation and Enhances Bone Resorption by Shifting Macrophage-Osteoclast Polarization
Mitochondrial Complex I reduces inflammation and increases bone breakdown by affecting certain immune cells.
research Matriptase: Potent Proteolysis on the Cell Surface
Matriptase is crucial for skin, hair, and immune cell health, and its imbalance can lead to cancer.
research Cell fate decisions: emerging roles for metabolic signals and cell morphology
Metabolic signals and cell shape influence how cells develop and change.
research Hox genes in development and beyond
Hox genes are crucial for development and tissue maintenance, affecting structures and functions throughout life.
research Vitamin D and the skin
research Sensations Evoked by Microstimulation of Single Mechanoreceptive Afferents Innervating the Human Face and Mouth
Microstimulation of certain facial and mouth nerves can evoke specific sensations, while deeper nerves may require multiple stimulations to affect perception.
research Quantification of the Vitamin D Receptor−Coregulator Interaction
Vitamin D receptor binds similarly to natural and synthetic ligands, affecting gene regulation.
research Deimination and Peptidylarginine Deiminases in Skin Physiology and Diseases
PADs are crucial for healthy skin and hair, and their imbalance can cause skin and hair disorders.
research Regulation of stem cell function by protein ubiquitylation
Protein ubiquitylation is crucial for controlling stem cell functions and could be targeted for cancer treatment.
research Characterization of hairless (Hr) and FGF5genes provides insights into the molecular basis of hair loss in cetaceans
Cetaceans lost hair due to changes in the Hr and FGF5 genes.