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GlossaryBromodeoxyuridine

synthetic nucleoside used to track cell proliferation

Bromodeoxyuridine, often abbreviated as BrdU, is a synthetic nucleoside that is commonly used in scientific research to measure cell proliferation. It works by incorporating into the DNA of dividing cells, allowing researchers to track and quantify new cell growth, which is particularly useful in studies of cancer, development, and tissue regeneration.

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research A practical guide for the study of human and murine sebaceous glands in situ

56 citations , September 2013 in “Experimental Dermatology”

The guide explains how to study human and mouse sebaceous glands using various staining and imaging techniques, and emphasizes the need for standardized assessment methods.

research Disruption of Smad4 in Mouse Epidermis Leads to Depletion of Follicle Stem Cells

43 citations , December 2008 in “Molecular biology of the cell”

Disrupting Smad4 in mouse skin causes early hair follicle stem cell activity that leads to their eventual depletion.

research Hair follicle elongation in organ culture of skin from newborn and adult mice

23 citations , May 1998 in “Journal of Dermatological Science”

Insulin or IGF-I is needed for hair growth in newborn mice, while minoxidil helps adult mouse hair grow, suggesting a way to study human hair loss.

The Success of Thread-Embedding Therapy in Generating Hair Regrowth in Mice Points to Its Possible Effect in Humans

research The Success of Thread-embedding Therapy in Generating Hair Re-growth in Mice Points to Its Possibly Having a Similar Effect in Humans

20 citations , December 2015 in “Journal of Pharmacopuncture”

Thread-embedding therapy helped hair grow back in mice and might do the same in humans.

research Hominis Placenta facilitates hair re-growth by upregulating cellular proliferation and expression of fibroblast growth factor-7

13 citations , July 2016 in “BMC Complementary and Alternative Medicine”

Hominis Placenta helps hair grow back by increasing cell growth and a specific growth factor.

research Comparative Hair Restorer Efficacy of Medicinal Herb on Nude (Foxn1nu) Mice

8 citations , January 2014 in “BioMed Research International”

Eclipta alba extract was found to be effective in promoting hair growth in hairless mice.

Cornu Cervi Pantotrichum Pharmacopuncture Solution Facilitates Hair Growth in C57BL/6 Mice

research Cornu cervi pantotrichum Pharmacopuncture Solution Facilitate Hair Growth in C57BL/6 Mice

4 citations , June 2016 in “Journal of Pharmacopuncture”

Cornu cervi pantotrichum pharmacopuncture solution helps mice grow hair by increasing hair follicle cell growth and a growth factor important for hair development.

research 0950 Exploring hair aging through ex vivo induction of DNA damage and senescence

July 2025 in “Journal of Investigative Dermatology”

BrdU speeds up hair follicle aging and reduces hair quality.

research Investigation on labeling skin stem cells of Inner Mongolia cashmere goats with BrdU

January 2009 in “Heilongjiang xumu shouyi”

Stem cells are present in goat hair follicles but decrease over time.

research Cell proliferation during fibre growth initiation in ferret hair follicles

January 1992 in “Proceedings of the New Zealand Society of Animal Production”

Ferret hair growth starts between 0 and 4 days after melatonin treatment, with cell growth peaking in the hair germ and declining as the hair matures.

research 5-Bromo-2′-deoxyuridine induced effluvium via p53-mediated CD326-positive keratinocyte apoptosis in C57BL/6 mice

August 2016 in “Journal of Dermatology”

A chemical called 5-Bromo-2′-deoxyuridine caused rapid hair loss in mice by killing certain skin cells through a specific cell death pathway.

Targeted Elimination of Follicular Label-Retaining Cells by Photo-Induced Cell Killing Caused a Defect in Follicular Renewal in Mice

research Targeted elimination of the follicular label-retaining cells by photo-induced cell killing caused a defect on follicular renewal on mice

8 citations , September 2002 in “Genes to Cells”

Killing specific cells in hair follicles can lead to hair growth problems in mice.

research Transcriptional Control of Epidermal Stem Cells

4 citations , January 2013 in “Advances in Experimental Medicine and Biology”

Certain transcription factors are key in controlling skin stem cell behavior and could impact future treatments for skin repair and hair loss.

Research on Skin-Derived Stem Cells for Skin Tissue Regeneration

research 皮膚組織の再生に向けた皮膚由来幹細胞に関する研究

March 2014 in “Institutional Repositories DataBase (IRDB)”

Skin-derived stem cells could help treat skin aging and pigmentation issues.

research Experimental Studies of Inner Ear Hair Cell Regeneration.

January 1995 in “Equilibrium Research”

Birds can regenerate inner ear hair cells from supporting cells, and mammals show potential for similar regeneration.

research Modulation of Hair Growth with Small Molecule Agonists of the Hedgehog Signaling Pathway

113 citations , September 2005 in “Journal of Investigative Dermatology”

Applying a special compound can promote hair growth without harmful side effects.

Beta-Catenin Signaling Increases in Proliferating NG2+ Progenitors and Astrocytes During Post-Traumatic Gliogenesis in the Adult Brain

research β-Catenin Signaling Increases in Proliferating NG2+ Progenitors and Astrocytes during Post-Traumatic Gliogenesis in the Adult Brain

67 citations , December 2009 in “Stem Cells”

β-Catenin signaling is involved in brain cell growth after injury and could be a therapy target.

research Ephrins Negatively Regulate Cell Proliferation in the Epidermis and Hair Follicle

39 citations , May 2010 in “Stem Cells”

Ephrins slow down skin and hair follicle cell growth.

research Quantitative Models for the Study of Hair Growth in Vivo^a

34 citations , December 1991 in “Annals of the New York Academy of Sciences”

The conclusion is that small hair follicles cause baldness in macaques, and treatments like antiandrogens and minoxidil can prevent hair loss and promote regrowth.

research Herbal Extracts Induce Dermal Papilla Cell Proliferation of Human Hair Follicles

24 citations , January 2015 in “Annals of Dermatology”

Herbal extracts may help hair grow and could be an alternative to synthetic hair loss treatments.

research Human placental extract exerts hair growth-promoting effects through the GSK-3β signaling pathway in human dermal papilla cells

20 citations , August 2015 in “International Journal of Molecular Medicine”

Human placental extract may help hair growth by affecting certain cell signals and could be more effective with minoxidil.

research Chrysanthemum zawadskii extract induces hair growth by stimulating the proliferation and differentiation of hair matrix

12 citations , May 2014 in “International Journal of Molecular Medicine”

Chrysanthemum zawadskii extract helps hair grow by stimulating hair cells.

Augmenting Peripheral Nerve Regeneration Using Rat Hair Follicle Stem Cells in Rats

research Augmenting Peripheral Nerve Regeneration Using Rat Hair Follicle Stem Cells (rHFSCs) in Rats

4 citations , June 2021 in “Basic and Clinical Neuroscience Journal”

Rat hair follicle stem cells can improve nerve repair and muscle function after injury.

research Enhancement of Hair Growth Through Stimulation of Dermal Papilla Cells in Human Follicular Dermal

August 2019 in “viXra”

Biofield Energy Healing significantly increased hair growth by making hair root cells grow more.

research Enhancement of Hair Growth through Stimulation of Dermal Papilla Cells in Human Follicular Dermal

January 2018 in “Open access journal of pharmaceutical research”

Biofield Energy Healing may increase hair growth by enhancing cell proliferation.

Synthesis and Structure–Activity Investigation of Iodinated Arylhydantoins and Arylthiohydantoins for Development as Androgen Receptor Radioligands

research Synthesis and structure–activity investigation of iodinated arylhydantoins and arylthiohydantoins for development as androgen receptor radioligands

6 citations , November 2004 in “Bioorganic & Medicinal Chemistry Letters”

Scientists created iodinated arylhydantoins and arylthiohydantoins that could potentially be used for imaging prostate cancer. Some versions with specific side-chains showed high potential for this use.