2 citations
,
January 2017 in “Journal of Pigmentary Disorders” Genetics, stress, and health issues can cause early hair greying, which affects self-esteem, and there's no cure, only hair dye.
60 citations
,
June 1997 in “Journal of The American Academy of Dermatology” Apoptosis is crucial for healthy skin and treating skin diseases.
11 citations
,
January 1992 in “PubMed” TGF-beta 1 and IGF-II mRNA have specific patterns in pig subcutaneous tissue, affecting fat and muscle development.
13 citations
,
May 2022 in “Cell discovery” The study found new details about human hair growth and suggests that preventing a specific biological pathway could potentially treat hair graying.
84 citations
,
October 2014 in “PLoS Genetics” Wnt signaling is essential for forming the skin's spinous layer through a BMP-FGF pathway.
December 2017 in “Journal of Cosmetic Dermatology” Researchers found certain genes are overactive and others are underactive in men with early balding, which could help create new treatments.
May 2026 in “Brazilian Journal of Hair Health” Bleaching damages hair the most, while dyes improve combability but still cause protein loss.
1 citations
,
August 2018 in “Journal of the American Academy of Dermatology” A young woman developed facial bumps before hair loss, which is unusual for her condition.
April 2018 in “Journal of Investigative Dermatology” Mutations in Far2 mice cause hair loss due to sebaceous gland issues.
9 citations
,
February 2002 in “International Journal of Dermatology” The patient's symptoms improved with treatment but recurred when the steroid dose was reduced, requiring ongoing therapy.
2 citations
,
March 1977 in “Journal of animal science/Journal of animal science ... and ASAS reference compendium” Defective mink guard hairs have split tips and missing cuticle cells, causing a metallic sheen.
April 2018 in “Journal of Investigative Dermatology” Aging reduces skin cell renewal and defense against germs due to TGFbeta, but blocking TGFbeta could help restore these functions.
85 citations
,
July 2002 in “Pigment Cell Research” The article concludes that while we understand a lot about how melanocytes age and how this can prevent cancer, there are still unanswered questions about certain pathways and genes involved.
11 citations
,
January 2016 in “Indian Journal of Plastic Surgery/Indian journal of plastic surgery” Direct brow lifting is effective, safe, and provides excellent long-lasting results for bald men or those with a high hairline.
The curly mutation in SELH/Bc mice affects hair and may help study human genetic disorders.
2 citations
,
November 2024 in “JAAD reviews.” Certain drugs can change hair color, either lightening or darkening it.
22 citations
,
June 2017 in “Stem cell reports” PTEN helps control the number and health of skin stem cells by working with the protein BMAL1.
103 citations
,
April 2005 in “Experimental dermatology” Prostaglandin F2alpha and related compounds can increase hair growth and darken hair in mice.
December 2014 in “Bali Medical Journal” Females have higher estrogen receptor levels in hair than males, and these levels decrease in white hair compared to black hair.
7 citations
,
January 2020 in “Nature” Stress turns hair white by depleting color-giving cells in hair follicles through a specific neurotransmitter related to the body's stress response.
4 citations
,
January 1992 in “The Tohoku Journal of Experimental Medicine” Zinc made mice's coarse hair turn into fine hair without affecting skin structure.
August 2017 in “Journal of the Dermatology Nurses' Association” Latisse (bimatoprost 0.03%) is widely used in dermatology but the document doesn't give detailed evidence or numbers.
September 2019 in “Revista Médica del Hospital General de México” Skin changes naturally as we get older.
2 citations
,
January 1990
April 2026 in “Indian Dermatology Online Journal” Premature graying of hair is more common in males and linked to family history, smoking, hair plucking, and low levels of certain vitamins and minerals.
21 citations
,
January 2007 in “Journal of the European Academy of Dermatology and Venereology” Travoprost can help eyelash growth but may cause darkening around the eyes.
April 2025 in “Pharmacognosy Magazine” Compound Baqia Danshen Liniment may effectively treat vitiligo by improving skin and hair pigmentation and reducing inflammation.
July 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” Blocking mTORC1 activity with rapamycin could help increase hair pigmentation and growth, potentially reversing gray hair.
Red light exposure slows aging in mice by improving fat metabolism.
65 citations
,
November 2004 in “Journal of the American Academy of Dermatology” Bimatoprost can cause excessive eyelash growth.