![[4-t-Butylphenyl]-N-(4-imidazol-1-yl phenyl)sulfonamide (ISCK03) Inhibits SCF/c-kit Signaling in 501mel Human Melanoma Cells and Abolishes Melanin Production in Mice and Brownish Guinea Pigs](/images/research/4eb017dc-711d-4926-bcd0-c3b8f48e3a99/small/19974.jpg)
26 citations
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July 2007 in “Biochemical Pharmacology” ISCK03 stops melanin production in human melanoma cells and lightens skin color in mice and guinea pigs.
53 citations
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September 2007 in “Veterinary dermatology” Allergic cats with yeast overgrowth improved with antifungal treatment.
9 citations
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November 2015 in “JAMA dermatology” A 91-year-old woman's hair turned black in one spot, with skin changes underneath.
6 citations
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April 2014 in “PubMed” A man got brown patches on his skin (melasma) after taking finasteride, a hair loss treatment.
2 citations
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March 2023 in “Frontiers in Medicine” Proper cleansing can resolve dermatosis neglecta, which may indicate underlying psychiatric issues.
2 citations
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January 2017 in “Indian dermatology online journal” A woman had a rare infection of both white piedra and head lice, which improved after 10 weeks of antifungal treatment.
2 citations
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June 2012 in “Dermatologica Sinica” Dermoscopy is useful for diagnosing and monitoring discoid lupus erythematosus by showing specific skin patterns.
1 citations
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December 2024 in “Case Reports in Dermatology” Cyclophosphamide likely causes skin darkening by affecting hair follicles.
1 citations
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October 2019 in “European Journal of Dermatology” Salicylic acid ointment effectively treated a toddler's skin condition.
This document discusses a pediatric case of follicular atopic dermatitis (AD) in a dark-skinned patient, highlighting the unique clinical presentation that can complicate diagnosis. The patient exhibited purplish to brownish follicular scaly papules symmetrically distributed across the body. Dermoscopic examination showed a white-brown background, perifollicular desquamation, and multiple dotted vessels, while histopathology confirmed the diagnosis. The report underscores the need for awareness of these specific features in dark skin to enhance diagnostic accuracy and treatment.
December 2024 in “Clinical Cosmetic and Investigational Dermatology” Elderly patients with eruptive skin bumps may have clear cell syringoma linked to glucose issues.
September 2024 in “Dermatologica Sinica” Early and accurate diagnosis of congenital smooth muscle hamartomas is crucial to distinguish them from other conditions.
July 2023 in “Clinical Cosmetic and Investigational Dermatology” Accurate diagnosis of granular parakeratosis is crucial for effective treatment and improvement.
February 2023 in “Indian journal of private psychiatry/Indian Journal of Private Psychiatry” Valproic acid can rarely cause reversible nail discoloration.
August 2016 in “Journal of the Portuguese Society of Dermatology and Venereology” Two women with darker skin had both frontal hair thinning and skin discoloration.
39 citations
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April 2001 in “Journal of The American Academy of Dermatology” Latanoprost, a glaucoma medication, caused excessive eyelid hair growth in many patients.
36 citations
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December 2004 in “British Journal of Dermatology” The cyst had unusual keratin spherules and resembled bone marrow.
32 citations
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July 2001 in “Journal of the American Academy of Dermatology” SLHA can be hard to diagnose and needs teamwork between specialists.
3 citations
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February 2016 in “Dermatologic Therapy” Using minoxidil and tretinoin on the skin, along with oral vitamin D, improved hair thickness and density in two girls with woolly hair.
2 citations
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March 2018 in “The Journal of Dermatology” The "color-transition sign" helps tell apart alopecia areata incognita from telogen effluvium by looking at hair color changes.
May 2026 in “Zenodo (CERN European Organization for Nuclear Research)” The study focused on formulating and evaluating a multipurpose herbal liquid shampoo using natural ingredients like Horse Gram, Amla, Fenugreek, Hibiscus, and Flaxseed extracts, known for their cleansing, nourishing, conditioning, anti-dandruff, and hair growth-promoting properties. The shampoo, adjusted to a pH of 5 for scalp compatibility, exhibited a brownish color, pleasant odor, and slightly thick texture. It demonstrated medium foam formation, effective cleansing action, and left hair feeling soft. The formulation, with a 20.8% solid content, showed no signs of skin irritation, confirming its safety for topical use.
May 2026 in “Zenodo (CERN European Organization for Nuclear Research)” The study focused on formulating and evaluating a multipurpose herbal liquid shampoo using natural ingredients like Horse Gram, Amla, Fenugreek, Hibiscus, and Flaxseed extracts, known for their cleansing, nourishing, conditioning, anti-dandruff, and hair growth-promoting properties. The shampoo, adjusted to a pH of 5 for scalp compatibility, exhibited a brownish color, pleasant odor, and slightly thick texture. It demonstrated medium foam formation, effective cleansing action, and left hair feeling soft. The formulation, with a 20.8% solid content, showed no signs of skin irritation, confirming its safety for topical use.
October 2025 in “Portuguese Journal of Dermatology and Venereology” Accurate diagnosis of facial skin tumors requires detailed analysis to distinguish between benign and malignant types.
April 2024 in “JURNAL ILMU KEFARMASIAN INDONESIA” The mud mask with 22.5% kaolin and pomegranate peel extract worked best.
November 2023 in “Berkala Ilmu Kesehatan Kulit dan Kelamin/Berkala ilmu kesehatan kulit dan kelamin (Periodical of dermatology and venerology)” A dermoscope helps accurately tell apart Pityrosporum folliculitis and Acne vulgaris.
May 2023 in “Journal of pharmacognosy and phytochemistry” The study established quality standards for Sphagneticola calendulacea stem and suggested it may have therapeutic benefits.
December 2017 in “JURNAL FARMANESIA” Red dragon fruit peel extract can effectively dye gray hair black.
September 2016 in “Journal of Dermatological Science” A specific mutation known for causing cancer is also found to cause a skin condition in a young girl.
3 citations
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March 2021 in “Cureus” A rare combination of halo nevi, nonsegmental vitiligo, and early gray hair can occur together.
1 citations
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October 2022 in “Dermatology practical & conceptual” Isolated patchy heterochromia with pili annulati can occur without other health issues.