321 citations
,
January 2012 in “Cell stem cell” TGF-β2 helps activate hair follicle stem cells by counteracting BMP signals.
41 citations
,
July 1994 in “Journal of Dermatological Science” Hair follicle cells need complex interactions to fully differentiate.
27 citations
,
December 2002 in “Journal of dermatological science” Merkel cells and Langerhans cells in hair follicles are closely connected and may interact.
6 citations
,
July 2009 in “Journal of Cutaneous Pathology” Hair follicle stem cells are key for hair growth and skin repair.
February 2025 in “Stem Cell Research & Therapy” Hair follicle regeneration is advancing but still faces challenges in stability and clinical use.
Current hair regeneration methods show promise but face challenges in maintaining cell effectiveness and creating the right environment for hair growth.
February 2024 in “International Journal of Molecular Sciences” Hair loss in Androgenetic Alopecia is caused by genetics, aging, and lifestyle, leading to hair follicle shrinkage and related health risks.
January 2006 in “Elsevier eBooks” Most vertebrates can regenerate skin, nails, and corneas, but only some can regenerate teeth and lenses.
6 citations
,
January 2019 in “The American Journal of Dermatopathology” The conclusion is that fat tissue in the skin is a new finding in Frontal fibrosing alopecia and may contribute to hair follicle and muscle degeneration.
133 citations
,
March 1999 in “Journal of Cutaneous Pathology” Trichoepitheliomas and some basal cell carcinomas likely come from hair follicle stem cells.
92 citations
,
December 2005 in “The Journal of clinical investigation/The journal of clinical investigation” Human hair follicle stem cells can be isolated using specific markers for potential therapeutic use.
46 citations
,
August 2006 in “Mechanisms of Development” Runx1 is crucial for proper hair structure and development.
31 citations
,
January 2009 in “Autoimmunity Reviews” Damage to hair follicle stem cells causes permanent hair loss and scarring in cutaneous lupus erythematosus.
23 citations
,
April 2016 in “Journal of Visualized Experiments” The method successfully isolates hair follicle stem cells from mice for research.
20 citations
,
January 2017 in “Experimental Dermatology” Igf1r helps regulate hair growth cycles.
10 citations
,
June 2016 in “Cell Transplantation” Sebaceous glands can help harvest hair follicle stem cells to regenerate skin and hair.
9 citations
,
September 2013 in “Journal of histochemistry and cytochemistry/The journal of histochemistry and cytochemistry” Matriptase is highly active in hair follicles and sebaceous glands, especially during hair growth phases.
8 citations
,
July 2020 in “Clinical, cosmetic and investigational dermatology” Excessive sun protection might cause frontal fibrosing alopecia by disrupting skin immune balance.
3 citations
,
April 2012 in “Cancer research” Mouse skin cancer progression involves a unique group of cells marked by ABCG2 and MTS24.
1 citations
,
January 2020 in “PubMed” Azelaic acid helps protect hair cells from UV damage and encourages hair growth by increasing certain gene expressions and proteins.
1 citations
,
July 2023 in “Communications biology” Removing Mediator 1 from certain mouse cells causes teeth to grow hair instead of enamel.
July 2025 in “Cell & Bioscience” Specific immune cells and pathways contribute to hair follicle inflammation and hair loss, suggesting potential treatments for lichen planopilaris.
March 2007 in “Journal of Plastic Reconstructive & Aesthetic Surgery” A new method was developed to create better skin models for healing and reconstruction.
July 2024 in “Journal of Investigative Dermatology” CD8+ T cells attack hair follicle stem cells, causing scarring and hair loss in Discoid Lupus.
April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” The study found that a key immune pathway protecting hair follicles is reduced in a mouse model of scarring hair loss.
September 2021 in “CRC Press eBooks” Lichen planopilaris causes permanent hair loss and scarring due to damage to hair follicles and can be mistaken for other hair loss conditions.
April 2012 in “Cancer Research” Stat3 influences keratinocyte stem cell behavior, affecting differentiation and migration.
2 citations
,
July 2022 in “Frontiers in Medicine” The cause of Frontal fibrosing alopecia, a type of hair loss, is complex, likely involving immune responses and genetics, but is not fully understood.
Melatonin may protect hair follicle stem cells from damage caused by chemotherapy.
207 citations
,
July 2006 in “Development” MTS24 marks a new type of skin cell that helps hair growth and repair.