Sensory neuron and Merkel-cell changes in the skin happen independently during normal skin maintenance.
Sensory neuron and Merkel cell changes in the skin happen independently during normal skin maintenance.
Skin stem cells in hair follicles are important for touch sensation.
Hair follicle stem cells are crucial for touch sensation and proper nerve structure in mice.
47 citations
,
May 1994 in “Experimental Brain Research” The mystacial pad's innervation in adult rats is more complex than previously thought.
22 citations
,
June 2021 in “Plants” Sterculia foetida seed extract shows promise for therapeutic use due to its anti-inflammatory and pain-relief properties.
2 citations
,
September 2025 in “Food Production Processing and Nutrition” Capsaicin offers health benefits and flavor but faces challenges in food use.
40 citations
,
November 2021 in “International Journal of Molecular Sciences” Mutant keratins cause inflammation in Epidermolysis Bullosa Simplex, suggesting targeting them could help treat the disorder.
26 citations
,
April 2006 in “Cephalalgia” Botulinum A toxin injections reduced pain and promoted hair regrowth in a woman with a rare form of alopecia areata.
7 citations
,
August 2023 in “Frontiers in Immunology” Targeting TRP channels may help reduce excessive scarring.
3 citations
,
October 2023 in “Journal of Pain” Certain proteins might predict surgical success in trigeminal neuralgia treatment.
1 citations
,
January 2025 in “IntechOpen eBooks” A comprehensive system is needed to ensure cosmetics are safe and effective, using global insights and new AI technologies.
January 2026 in “International Journal of Molecular Sciences” Topical peptides may offer safer, effective pain relief and healing for wounds.
November 2024 in “Frontiers in Medicine” Cirrhosis affects quality of life with various symptoms, requiring a holistic, multidisciplinary approach for management.
12 citations
,
March 2022 in “Development” Mechanical forces are crucial in shaping our sensory organs during development.
11 citations
,
July 2015 in “Journal of Anatomy” SLVs help maintain muscle stretch sensitivity and could aid in treating hypertension and muscle spasticity.
1 citations
,
April 2023 in “Science Advances” High levels of ERK activity are key for tissue regeneration in spiny mice, and activating ERK can potentially redirect scar-forming healing towards regenerative healing in mammals.
25 citations
,
January 2013 in “Journal of Cell Science” Tenascin-C and tenascin-W help control stem cell movement and growth in whisker follicles.
February 2025 in “Folia Medica” Synthetic hyaluronic acid speeds up wound healing.
September 2016 in “DOAJ (DOAJ: Directory of Open Access Journals)” Jujube essential oil promotes hair growth.
123 citations
,
November 2003 in “Neuroscience Letters” TRPV4 helps sense pressure in mouse skin.
7 citations
,
April 2014 in “Cell biology international” Melatonin treatment helps improve skin health in postmenopausal rats.
19 citations
,
February 2013 in “Journal of Investigative Dermatology” Touch domes in human skin are complex sensory structures not directly linked to hair.
1 citations
,
January 2012 in “Elsevier eBooks” The document concludes that the skin is a complex organ providing protection, sensation, and healing, with challenges in treating conditions like itchiness.
Collagen VI is crucial for nerve function and affects wound-induced hair regrowth.
48 citations
,
May 2021 in “Molecules” Plant extracts from dry flowers can be used as safe, effective dyes in cosmetics, offering skin protection and anti-aging benefits.
11 citations
,
November 2009 in “Brazilian Journal of Medical and Biological Research” Young C57BL/6 mice heal better than BALB/c mice, and older mice heal faster but regenerate worse.
11 citations
,
January 2005 in “Brazilian Journal of Medical and Biological Research” Hairless USP mice have enlarged skin cysts as they age.
5 citations
,
July 2022 in “Journal of Clinical Medicine” Long COVID-19 patients with skin pain might have a nerve condition that responds to a medication called gabapentin.
12 citations
,
July 2016 in “British journal of dermatology/British journal of dermatology, Supplement” Different hair fiber development might explain why hair loss severity varies in patients with a specific genetic mutation, and treatments that thicken hair could help.