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GlossaryC-reactive protein

protein produced by the liver in response to inflammation

C-reactive protein (CRP) is a substance produced by the liver in response to inflammation. Elevated levels of CRP in the blood can indicate acute inflammation, infection, or chronic inflammatory conditions such as rheumatoid arthritis or cardiovascular disease. A CRP test is commonly used by healthcare professionals to assess the presence and severity of inflammation in the body.

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Associations Between Transition-Specific Stress Experience, Nocturnal Decline in Ambulatory Blood Pressure, and C-Reactive Protein Levels Among Transgender Men

research Associations between transition‐specific stress experience, nocturnal decline in ambulatory blood pressure, and C‐reactive protein levels among transgender men

40 citations , November 2011 in “American Journal of Human Biology”

Stress from being transgender is linked to higher blood pressure at night and more inflammation, which may affect heart health.

research C‐reactive protein promotes adhesion of monocytes to endothelial cells via NADPH oxidase‐mediated oxidative stress

24 citations , January 2012 in “Journal of Cellular Biochemistry”

C-reactive protein helps monocytes stick to blood vessel cells by causing oxidative stress.

research Evaluation of the serum C‐reactive protein–albumin ratio and its relationship with disease severity IN alopecia areata: A prospective case–control study

3 citations , October 2022 in “Journal of Cosmetic Dermatology”

CAR is a useful marker for assessing alopecia areata severity.

research C‐reactive protein as a novel biomarker for vitamin D deficiency in alopecia areata

March 2024 in “Skin research and technology”

High CRP levels could indicate vitamin D deficiency in people with alopecia areata.

Increased Serum C-Reactive Protein Levels Imply Chronic Inflammation in Men with Benign Prostatic Hyperplasia and Predominant Storage Lower Urinary Tract Symptoms

research 1746 INCREASED SERUM C-REACTIVE PROTEIN LEVELS IMPLIES CHRONIC INFLAMMATION IS INVOLVED IN MEN WITH BENIGN PROSTATIC HYPERPLASIA AND PREDOMINANT STORAGE LOWER URINARY TRACT SYMPTOMS

April 2013 in “The Journal of Urology”

Higher CRP levels suggest chronic inflammation is linked to bladder-related urinary symptoms in men with enlarged prostates.

research Long-term reduction of C-reactive protein by LDL apheresis

October 2002 in “Atherosclerosis Supplements”

LDL apheresis lowers inflammation and cardiovascular risk by reducing CRP levels long-term.

research A study on relationship between androgenetic alopecia and cardiovascular risk using high sensitivity C-reactive protein and galectin-3 in men with early onset baldness.

December 2021 in “Biomarkers”

Men with early baldness have similar heart risk factors as others, but certain proteins are linked to higher heart disease risk.

research Assessment of cardiovascular risk in patients with androgenetic alopecia using high-sensitivity C-reactive protein and lipoprotein a

January 2019 in “Journal of the Egyptian Women's Dermatologic Society (Print)”

People with androgenetic alopecia have a higher risk of heart disease.

research Results of Complete Blood Cell Count, Fasting Blood Sugar, Rheumatoid Factor, C - Reactive Protein, Anti Nuclear Antibody and Thyroid Function Tests in Patients with Alopecia Areata

April 2011 in “Medical Journal of Tabriz University of Medical Sciences and Health Services”

Many patients with Alopecia Areata have underlying autoimmune disorders, especially thyroid issues.

research More than 50 Long-term effects of COVID-19: a systematic review and meta-analysis

114 citations , January 2021 in “medRxiv (Cold Spring Harbor Laboratory)”

COVID-19 can cause over 50 long-term symptoms, with fatigue and headache being the most common.

research Zinc: An Essential Trace Element for Parenteral Nutrition

114 citations , October 2009 in “Gastroenterology”

Zinc is crucial for nutrition, especially in patients with specific health conditions, and requires careful supplementation and monitoring.

research Effects of Melatonin Supplementation on Hormonal, Inflammatory, Genetic, and Oxidative Stress Parameters in Women With Polycystic Ovary Syndrome

81 citations , May 2019 in “Frontiers in Endocrinology”

Melatonin may improve some hormonal and inflammatory issues in women with PCOS.

research Clinical and immunologic parameters during thalidomide treatment of lupus erythematosus

64 citations , May 2000 in “International Journal of Dermatology”

Thalidomide improved lupus symptoms but caused nerve damage in some patients.

research Protective effects of melatonin against metabolic and reproductive disturbances in polycystic ovary syndrome in rats

41 citations , September 2014 in “Journal of Pharmacy and Pharmacology”

Melatonin may help treat PCOS symptoms in rats.

research Inflammatory perspectives of polycystic ovary syndrome: role of specific mediators and markers

31 citations , December 2023 in “Middle East Fertility Society Journal”

PCOS is linked to inflammation, and certain markers could help in its treatment.

Decreased CD200R Expression on Monocyte-Derived Macrophages Correlates with Th17/Treg Imbalance and Disease Activity in Rheumatoid Arthritis Patients

research Decreased CD200R expression on monocyte-derived macrophages correlates with Th17/Treg imbalance and disease activity in rheumatoid arthritis patients

31 citations , February 2014 in “Inflammation Research”

Lower CD200R1 on certain immune cells is linked to more severe rheumatoid arthritis and immune imbalance.

The Association Between Low-Grade Systemic Inflammation and Skin Diseases: A Cross-Sectional Survey in the Northern Finland Birth Cohort 1966

research The Association Between Low Grade Systemic Inflammation and Skin Diseases: A Cross-sectional Survey in the Northern Finland Birth Cohort 1966

27 citations , September 2017 in “Acta dermato-venereologica”

Adults with certain skin conditions may have higher levels of inflammation in their body.

research Evaluation of cardiac risk marker levels in obese and non-obese patients with polycystic ovaries

21 citations , July 2016 in “Gynecological Endocrinology”

Obese and non-obese women with PCOS have higher heart risk markers, especially if they are obese.

Expression of 11β-Hydroxysteroid Dehydrogenase Type 1 in Visceral and Subcutaneous Adipose Tissues of Patients with Polycystic Ovary Syndrome Is Associated with Adiposity

research Expression of 11β-hydroxysteroid dehydrogenase type 1 in visceral and subcutaneous adipose tissues of patients with polycystic ovary syndrome is associated with adiposity

18 citations , December 2010 in “The Journal of Steroid Biochemistry and Molecular Biology”

Increased HSD11B1 enzyme expression is linked to higher body fat and insulin resistance.

research Risk factors for diabetic foot ulcers mortality and novel negative pressure combined with platelet-rich plasma therapy in the treatment of diabetic foot ulcers

14 citations , December 2022 in “Frontiers in Pharmacology”

Combining negative pressure therapy with platelet-rich plasma speeds up healing and lowers death risk in diabetic foot ulcers.

research Beyond Hormones: A Systematic Review of the Risk of Cardiovascular Diseases in Polycystic Ovary Syndrome

10 citations , November 2024 in “Cureus”

Women with PCOS have a higher risk of heart disease due to factors like insulin resistance and obesity.

research Benign prostatic hyperplasia, metabolic syndrome and androgenic alopecia: Is there a possible relationship?

7 citations , February 2016 in “Arab journal of urology”

People with early hair loss may have a higher chance of enlarged prostate and metabolic syndrome, so they should be checked for urinary and metabolic issues.

research Evaluation of several immune and inflammatory indicators and their association with alopecia areata

5 citations , September 2021 in “Journal of cosmetic dermatology”

People with alopecia areata often have abnormal thyroid hormones, thyroid antibodies, antinuclear antibodies, low vitamin D, and high C-reactive protein levels.

Erythema Nodosum Leprosum: Immunoglobulin G Subclasses and Complement Activation

research Erythema Nodosum Leprosum

5 citations , February 1977 in “Archives of Dermatology”

The study suggests that complement activation, not immunoglobulins, may be important in erythema nodosum leprosum.

research Biomarkers in alopecia Areata: A systematic review and meta-analysis.

4 citations , April 2023 in “Autoimmunity reviews”

High levels of IL6 and CRP, and low levels of vitamin D, might be indicators of alopecia areata.

Gender Difference in the Relationship Between Ferritin and Homeostasis Model Assessment of Insulin Resistance in Non-Diabetic Korean Adults

research Gender difference in the relationship between the ferritin and homeostasis model assessment of insulin resistance in non-diabetic Korean adults

4 citations , June 2018 in “PLOS ONE”

Iron levels are linked to insulin resistance in men and postmenopausal women, but not in premenopausal women.

research Oxidative stress and antioxidant markers in patients with alopecia areata: A comparative cross-sectional study

3 citations , July 2022 in “Indian journal of dermatology, venereology, and leprology”

Patients with alopecia areata have higher oxidative stress and lower antioxidant levels.

research Relationship between hair shedding and systemic inflammation in COVID-19 pneumonia

3 citations , March 2022 in “Annals of Medicine”

Hair shedding after COVID-19 is more linked to the disease's severity and inflammation rather than hormones, with women at higher risk.

research Effects of supplementation with two probiotic strains (Lactobacillus helveticus and Bifidobacterium longum) on hormonal status, oxidative stress, and clinical symptoms in women with polycystic ovary syndrome: a randomized clinical trial

2 citations , November 2025 in “Nutrition Journal”

Probiotic supplements may help reduce inflammation and oxidative stress in women with PCOS.

research Cell‐free DNA is elevated in the serum of patients with hidradenitis suppurativa

2 citations , December 2022 in “The Journal of Dermatology”

Patients with hidradenitis suppurativa have higher levels of cell-free DNA in their blood.