45 citations
,
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,
August 2005 in “Bioorganic & medicinal chemistry” New compounds with carborane showed anti-androgen effects similar to flutamide.
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,
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,
January 2021 in “Research” MCSA hydrogels can effectively treat melanoma and aid wound healing.
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,
March 2020 in “Antibiotics” Rosemary extracts with carnosic acid and carnosol can reduce the harmfulness of Staphylococcus aureus without stopping its growth.
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,
May 2008 in “Fertility and Sterility” Insulin resistance might not be enough to worsen blood vessel function in young, nonobese women with polycystic ovary syndrome.
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,
January 2008 in “Fertility and Sterility” Longer CAG repeat lengths in the androgen receptor gene are linked to higher testosterone levels in women with PCOS.
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,
March 2015 in “PLOS ONE” Fibroblast Growth Factor-9 (FGF-9) can help improve heart function in diabetic mice after a heart attack by reducing inflammation and harmful changes to the heart's structure.
43 citations
,
July 2023 in “Pharmaceuticals” Caffeine can boost health, prevent diseases, and improve performance, with new methods enhancing its benefits.
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,
December 2006 in “The American journal of pathology” Edar signaling is crucial for controlling hair growth and regression.
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,
October 2006 in “Journal of Cell Science” Keratin 10 end domains may increase skin cancer risk by reducing cell death.
42 citations
,
December 2016 in “Cell Death & Differentiation” Damaging mitochondrial DNA in mice speeds up aging due to increased reactive oxygen species, not through the p53/p21 pathway.
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,
July 2012 in “PLOS ONE” Estrogen can temporarily slow down hair growth but this can be reversed.
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,
January 2009 in “Colloids and Surfaces B: Biointerfaces” A certain surfactant sticks to human hair, making it change from water-repelling to water-attracting, which could help in hair conditioning.
41 citations
,
September 2003 in “Journal of Investigative Dermatology” Overexpression of COX-2 causes early hair loss in mice, but can be prevented with a COX-2 inhibitor.
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,
April 2014 in “Genes & Development” Hormones during pregnancy and lactation keep skin stem cells inactive, preventing hair growth.
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,
June 2013 in “Scientific Reports” A gene variant in KRT71 causes the curly fur in Selkirk Rex cats.
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,
January 2013 in “Frontiers in Endocrinology” Finger length ratios are not linked to the number of specific gene repeats affecting testosterone sensitivity.
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,
April 1999 in “Journal of Histochemistry & Cytochemistry” S100A3 protein is mainly found in specific parts of human hair cells.
40 citations
,
November 1998 in “The journal of investigative dermatology/Journal of investigative dermatology” S100A3 protein is crucial for hair shaft formation in mice.
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,
July 1995 in “Toxicologic Pathology” Minoxidil can harm dog's heart.
40 citations
,
November 2005 in “The journal of investigative dermatology/Journal of investigative dermatology” Different melanocyte types in hair follicles either survive or die during the catagen phase.
40 citations
,
September 2003 in “Journal of the American Animal Hospital Association” Hypothyroidism in dogs can cause aggression, which can be treated with thyroid therapy.
39 citations
,
December 2012 in “The American Journal of Human Genetics” Mutations in the SNRPE gene cause hereditary hair loss.
39 citations
,
June 2023 in “Frontiers in Medicine” Calcium Hydroxylapatite may help skin regeneration and improve skin appearance.
38 citations
,
September 2019 in “Chinese Medical Journal” Using steroids can increase the risk of heart problems.
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,
December 2009 in “Therapeutic Advances in Medical Oncology” The conclusion suggests that prostate cancer should be classified by castration status and that new therapies targeting androgen receptor signaling show promise.
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,
June 2018 in “Plant & cell physiology/Plant and cell physiology” Changing the amount of PLC5 in Arabidopsis affects root growth and drought resistance, with less PLC5 slowing root growth and more PLC5 improving drought tolerance but hindering root hair growth.
38 citations
,
June 2015 in “PubMed” Calcipotriol cream can effectively and safely treat mild-to-moderate patchy hair loss.
37 citations
,
October 2013 in “PLoS ONE” MicroRNAs play a key role in wool growth in Tibetan sheep.