research The Nuclear Vitamin D Receptor: Biological and Molecular Regulatory Properties Revealed
The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.
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research Epithelial‐to‐mesenchymal transition in cutaneous wound healing: Where we are and where we are heading
The document concludes that a better understanding of cell changes during wound healing could improve treatments for chronic wounds and other conditions.
research Double-blind, placebo-controlled evaluation of topical minoxidil in extensive alopecia areata
Minoxidil helps hair growth in 63.6% of alopecia patients, with 27.3% having excellent results.
research Role of cholesterol sulfate in epidermal structure and function: Lessons from X-linked ichthyosis
Cholesterol sulfate buildup due to a genetic mutation disrupts the skin barrier, leading to the scaling skin seen in X-linked ichthyosis.
research VP-16-213 (etoposide): The mandrake root from Issyk-Kul
Etoposide is effective in treating several cancers, especially small cell lung cancer, with acceptable side effects.
research Wound Healing: A Paradigm for Regeneration
Wound healing insights can improve regenerative medicine.
research Topical minoxidil (3%) in extensive alopecia areata, including long-term efficacy
3% topical minoxidil effectively treats extensive alopecia areata with few side effects.
research Trichoscopy
Trichoscopy is a non-invasive way to diagnose hair and scalp problems without needing hair samples.
research Rhythmic expression of circadian clock genes in human leukocytes and beard hair follicle cells
Human leukocytes and beard hair follicle cells have internal daily clocks, and PER1 and PER3 genes may indicate individual circadian rhythms.
research Hormonal changes in menopause: do they contribute to a ‘midlife hair crisis’ in women?
Menopause-related hormonal changes affect hair but are not the only cause of hair changes in middle-aged women.
research Adolescent hair loss
Hair loss in teenagers is hard to treat and lacks a cure, with some treatments available depending on the type of hair loss.
research Medication-Induced Repigmentation of Gray Hair: A Systematic Review
Some medications might reverse gray hair, especially those that reduce inflammation or stimulate pigment production, and vitamin B might help.
research A Systematic Review of the Outcome of Hair Transplantation in Primary Scarring Alopecia
Hair transplantation may work for some types of scarring alopecia, but results vary and more research is needed.
research State-dependent signaling by Cav1.2 regulates hair follicle stem cell function
Cav1.2 affects hair growth and could be a target for hair loss treatments.
research Genome-wide association study of skin complex diseases
Genetic variants linked to ten skin diseases were found, showing both immune and non-immune factors play a role.
research The effects of particle properties on nanoparticle drug retention and release in dynamic minoxidil foams
Particle properties affect drug retention and release in minoxidil foams, with lipid nanoparticles having higher loading capacity.
research Aqueous extract of Asiasari radix inhibits formalin-induced hyperalgesia via NMDA receptors
Asiasari radix extract may relieve certain types of pain by affecting GABA and NMDA receptors.
research Dermatologic Problems of Older Women
Older women face various skin issues like dryness and thinning, and treatments are available but can have side effects; proper skin care and legal health decisions are important.
research TSPO activation modulates the effects of high pressure in a rat ex vivo glaucoma model
Activating TSPO helps protect the retina from damage caused by high eye pressure in glaucoma.
research An evaluation of the safety and efficacy of bimatoprost for eyelash growth in pediatric subjects
Bimatoprost is safe and improves eyelash growth in healthy kids but not in those with eyelash loss from chemotherapy or alopecia.
research Dermatoscopic findings of syphilitic alopecia
Dermoscopy helps diagnose syphilitic alopecia, and treatment with penicillin can regrow hair.
research Human platelet lysate versus minoxidil stimulates hair growth by activating anagen promoting signaling pathways
Both human platelet lysate and minoxidil can promote hair growth, but they affect different genes and cell survival rates.
research Neurotrophin-4 modulates the mechanotransducer Cav3.2 T-type calcium current in mice down-hair neurons
Neurotrophin-4 increases calcium current in specific mouse neurons through the PI3K pathway.
research Effect of immunization against melatonin on seasonal fleece growth in feral goats
Immunizing goats against melatonin can temporarily change their cashmere growth cycles and increase fleece production.
research Comparison of mitochondrial transplantation by using a stamp-type multineedle injector and platelet-rich plasma therapy for hair aging in naturally aging mice
Mitochondrial therapy and platelet-rich plasma therapy both stimulated hair regrowth in aging mice, with mitochondrial therapy showing similar effectiveness to plasma therapy.
research Identification and Characterisation of a Novel Pathogenic Mutation in the Human Lipodystrophy Gene AGPAT2
A new mutation in the AGPAT2 gene causes severe fat tissue loss and related health issues by reducing the protein's levels.
research Baldness may be caused by the weight of the scalp: Gravity as a proposed mechanism for hair loss
Baldness might be caused by scalp weight pressing on hair follicles.
research Two mouse mutations mapped to chromosome 11 with differing morphologies but similar progressive inflammatory alopecia
Two mouse mutations cause similar hair loss despite different skin changes.
research Combined analysis of two multicenter studies of finasteride 5 mg in the treatment of symptomatic benign prostatic hyperplasia
Finasteride 5 mg effectively reduces urinary symptoms and PSA levels in men with enlarged prostates, with few sexual side effects.
research The dermatology consultant: A retrospective analysis of inpatient dermatology
Dermatologists greatly affect inpatient diagnosis and treatment of skin conditions, especially in spotting infections in patients with weakened immune systems.