August 2021 in “Institutional Repositories DataBase (IRDB)” Rubbing lotion or cream increases caffeine absorption through the skin but not rhododendrol.
1 citations
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July 2023 in “Cureus” Some treatments for hereditary hair loss are effective but vary in results and side effects; new therapies show promise but need more research.
32 citations
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December 2017 in “Journal of Drug Delivery Science and Technology” Minoxidil and caffeine in transfersomes improve hair growth treatment.
July 2022 in “International Journal of Applied Pharmaceutics” The optimized caffeine formula improved hair growth and penetrated all skin layers.
December 2024 in “http://isrctn.com/” MpowerTM may improve hair growth and satisfaction more than plain minoxidil, with mild side effects.
January 2026 in “AAPS PharmSciTech” Liposomal formulations with caffeine and cafestol enhance skin penetration effectively.
21 citations
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April 2021 in “Biofabrication” The study created a skin model with realistic blood vessels that improves skin grafts and testing for drug delivery.
September 2025 in “medRxiv (Cold Spring Harbor Laboratory)” Using Centella asiatica EV and growth factors improves scalp health and hair growth.
1 citations
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March 2018 in “Dermatologie pro praxi” Most over-the-counter hair loss treatments lack strong evidence of effectiveness, except for minoxidil, which works but stops working if you stop using it.
September 2023 in “Authorea (Authorea)” Certain peptides, caffeine, taurine, and an iron complex may improve hair regrowth when used with minoxidil and finasteride for hair loss.
2 citations
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July 2018 in “Elsevier eBooks” Some supplements may help with hair loss, but there's not enough strong evidence to recommend them without doctor advice.
5 citations
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September 2023 in “International Journal of Molecular Sciences” FucoPol hydrogel membranes are promising for delivering drugs on the skin.
3 citations
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January 2023 in “International Journal of Cosmetic Science” Coffee and its by-products are promising for skin health benefits in cosmetics and help reduce environmental impact.
2 citations
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January 2022 in “Dermatologic Therapy” Natural products like saw palmetto, caffeine, melatonin, marine extracts, rosemary oil, procyanidin, pumpkin seed oil, and cannabidiol oil could potentially treat male hair loss.
153 citations
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October 2012 in “Skin Pharmacology and Physiology” Caffeine in cosmetics may reduce cellulite, protect skin, and stimulate hair growth, but more research is needed on its use and effects.
Caffeine therapy helped hair recovery after chemical and traction damage.
11 citations
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July 2012 in “International Journal of Trichology” Caffeine may help hair growth in hereditary hair loss.
Caffeine can potentially treat common hair loss by counteracting hair follicle shrinkage caused by hormones.
46 citations
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January 2008 in “Journal of cosmetic dermatology” Caffeine and siloxanetriol alginate caffeine in emulsion form can reduce fatty cell size and number, potentially treating cellulite effectively.
19 citations
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November 2011 Using systemic drugs as creams for skin conditions shows promise, but more research is needed to confirm their effectiveness and safety.
3 citations
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October 2018 in “Skin appendage disorders” New treatment reduces hair shedding and increases hair density in women with early hair loss.
January 2026 in “Frontiers in Medicine” PP-PTKL may help treat hair greying, but more testing is needed.
January 2022 in “International Journal of Health Science” Topical products, especially specific shampoos, are effective in treating androgenetic alopecia by delivering active ingredients to hair follicles and improving hair quality.
May 2024 in “Journal of cosmetic dermatology” A shampoo with caffeine and adenosine may help prevent hair loss and thicken hair.
6 citations
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January 2020 in “Skin Pharmacology and Physiology” HIF-1α stimulators, like deferiprone, work as well as popular hair loss treatments, minoxidil and caffeine, in promoting hair growth.
September 2025 in “Journal of Drug Delivery Science and Technology” Vitamin D3-coated nanoparticles effectively deliver caffeine for alopecia treatment with minimal side effects.
July 2023 in “International journal of research publications” Green coffee bean extract didn't grow hair but reduced a hair loss-related enzyme in rats.
The caffeine shampoo for hair loss is stable and suitable for use.
61 citations
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January 2018 in “Cosmetics” Coffee silverskin may be a beneficial and safe ingredient for cosmetics, offering hydration, firmness, and potential hair growth benefits.
43 citations
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July 2023 in “Pharmaceuticals” Caffeine can boost health, prevent diseases, and improve performance, with new methods enhancing its benefits.