research 5 Alpha-reductase inhibitors: whatʼs new?
A new drug, dutasteride, is at least as effective as the older drug, finasteride, for treating enlarged prostate and may have additional uses.
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30-60 / 1000+ resultsresearch Subcellular localization of the five members of the human steroid 5α-reductase family
All five human steroid 5α-reductase enzymes are found in the endoplasmic reticulum.
research Facial Hidradenitis Suppurativa in a 28-Year-Old Male Responding to Finasteride
Finasteride helped treat a 28-year-old's facial skin condition.
research Nomenclature Proposal for the Zones and Landmarks of the Balding Scalp
Michael L. Beehner proposed a standardized way to describe balding areas on the scalp to help hair restoration experts communicate better.
research A translational approach to improve therapeutics in atopic dermatitis and beyond
New treatments for atopic dermatitis and alopecia areata have been developed using a targeted approach.
research Case report: Dermatosis neglecta mimicking pemphigus foliaceus in association with obsessive–compulsive disorder
Proper cleansing can resolve dermatosis neglecta, which may indicate underlying psychiatric issues.
research Fructose-1,6-bisphosphate aldolase A levels decrease in hair keratinocytes during androgenetic alopecia
ALDOA levels drop in hair cells during hair loss.
research Recent European legal developments on second medical uses and dosage regimes
European patent law now allows patents for new uses and dosages of known drugs, but protection scope is unclear.
research Telogen Effluvium
The debate focuses on the role of catagen and hair shedding mechanisms in telogen effluvium.
![Minoxidil and Its Use in Hair Disorders: A Review [Corrigendum]](/images/research/d5b5fb1b-96a4-4e61-a554-3fe9a1f78497/small/11472.jpg)
research <p>Minoxidil and Its Use in Hair Disorders: A Review [Corrigendum]</p>
Low-dose Minoxidil combined with Spironolactone helps reduce hair loss and improve hair density in women, with some mild side effects.
research Minoxidil and Its Use in Hair Disorders: A Review [Corrigendum]
Minoxidil 0.25 mg with spironolactone 25 mg reduces hair loss and improves hair density in women.
research Applications of Hair as a Record of Systemic Exposure to Cortisol
Hair cortisol content can indicate cortisol exposure and varies with age, puberty, and BMI in youth.
research Decision letter: Arabidopsis formin 2 regulates cell-to-cell trafficking by capping and stabilizing actin filaments at plasmodesmata
Arabidopsis Formin 2 stabilizes actin filaments to aid cell-to-cell trafficking.
research Author response: Stimulation of hair follicle stem cell proliferation through an IL-1 dependent activation of γδT-cells
IL-1 and IL-7 help activate cells that boost hair follicle stem cell growth, aiding wound healing.
research Author reply
Demodex may be linked to blepharitis, and treatments like tea tree oil and ivermectin can help.
research Reply to: Is melatonin useful in alopecia: critical appraisal of a randomized trial?
Melatonin may help treat hair loss and needs more research.
research Latest Information on Alopecia
New therapies for hair loss are being developed due to advances in understanding hair growth mechanisms.
research Clarification
Dr. Yarborough denied endorsing Derma Genesis and was mistakenly represented due to his office manager's error; also, over 30% of tested skin products were contaminated with bacteria.
research Letter to the Editor Etiquette
Experts discussed sedation, hair transplant techniques, and called for respectful professional communication.
research [Dermatologic indications for anti-androgenic treatment].
Antiandrogenic treatments can effectively manage certain skin conditions by using female hormones.
research Recurring transient lymphadenopathy after microneedling with platelet-rich plasma for androgenetic alopecia
Microneedling with platelet-rich plasma can cause temporary, painful lymph node swelling in some patients.
research Regeneration of Hair Follicles Is Modulated by Flightless I (Flii) in a Rodent Vibrissa Model
Flightless I protein affects hair growth, with low levels delaying it and high levels increasing hair length in rodents.
research Sessualità e sindrome dell’ovaio policistico
Women with PCOS are more likely to experience sexual dysfunction, but lifestyle changes and weight loss can improve sexual function.
research Skeletal Site-Dependent Expression of the Androgen Receptor in Human Osteoblastic Cell Populations
Higher androgen levels and site-specific AR expression cause sex-related skeletal differences, and certain steroids can boost AR expression and androgen effects in bone cells.
research Physiological Insights from the Vitamin D Receptor Knockout Mouse
research A Single Injection of the Anabolic Bone Agent, Parathyroid Hormone–Collagen Binding Domain (PTH–CBD), Results in Sustained Increases in Bone Mineral Density for up to 12 Months in Normal Female Mice
A single injection of PTH–CBD can increase bone density for up to a year.
research Bone mineral density in hyperandrogenic amenorrhoea
Women with hyperandrogenic amenorrhea have similar bone density to healthy women but lower than androgenized women without amenorrhea, and high DHEAS levels might affect bone density.
research Presence of a Deletion Mutation (c.716delA) in the Ligand Binding Domain of the Vitamin D Receptor in an Indian Patient with Vitamin D-Dependent Rickets Type II
A genetic mutation caused severe rickets and alopecia in an Indian patient, but high-dose calcium and phosphate treatment improved their condition.
research The mineralization of hair follicle tissue
Hair follicle tissue can induce mineral formation, likely due to a potent nucleator.
research The mineralization of hair follicle tissue
Hair follicles in injured skin can quickly accumulate minerals, especially calcium and phosphorus.