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research Hereditary vitamin D resistant rickets (HVDRR) case series: phenotype, genotype, conventional treatment, and adjunctive cinacalcet therapy

1 citations , January 2024 in “Pediatric Endocrinology Diabetes and Metabolism”

This study examined 8 patients with hereditary vitamin D resistant rickets (HVDRR) from 5 Saudi families, all of whom exhibited alopecia and secondary hyperparathyroidism. Genetic analysis identified 3 distinct mutations in the vitamin D receptor gene. Four patients were treated with high-dose calcium alone, while the other 4 received additional cinacalcet, a calcimimetic. The use of cinacalcet showed promise in improving serum PTH levels without causing hypocalcaemia, suggesting it may be a safe and valuable adjunctive therapy. However, the response to treatment varied, and further research is needed to confirm these findings.

research STUDIES ON A SKIN CALCIFYING SYSTEM

12 citations , December 1965 in “Immunology and Cell Biology”

Mild skin injury can trigger mineral deposits in rat skin, even without full calciphylactic response.

research Systemic and Topical Factors Involved in the Production of Experimental Cutaneous Calcinosis11From the Institut de Médecine et de Chirurgie expérimentales, Université de Montréal, Montréal, Canada.

9 citations , July 1961 in “Journal of Investigative Dermatology”

Cutaneous calcinosis can be induced in young animals using certain compounds, but only in specific areas and with high mortality.

research Expression of Calcyclin, a Calcium-Binding Protein, in the Keratogenous Region of Growing Hair Follicles

40 citations , March 1991 in “Journal of Investigative Dermatology”

research Calcipotriol/dithranol

March 2019 in “Reactions Weekly”

research Intracellular Calcium Mobilization in Response to Ion Channel Regulators via a Calcium-Induced Calcium Release Mechanism

19 citations , December 2016 in “The journal of pharmacology and experimental therapeutics/The Journal of pharmacology and experimental therapeutics”

Certain drugs increase calcium levels in cancer cells by triggering internal calcium release.

Influence of the Alkylsulfonylamino Substituent Located at the 6-Position of 2,2-Dimethylchromans Structurally Related to Cromakalim: From Potassium Channel Openers to Calcium Entry Blockers?

research Influence of the alkylsulfonylamino substituent located at the 6-position of 2,2-dimethylchromans structurally related to cromakalim: From potassium channel openers to calcium entry blockers?

6 citations , April 2014 in “European journal of medicinal chemistry”

New compounds similar to cromakalim were less effective at inhibiting insulin release but improved in solubility and one acted as a calcium entry blocker, not a potassium channel opener.

research Calcitriol and Alopecia—Is it the Hair Apparent?

May 2003 in “Journal of clinical oncology”

research Hereditary vitamin D rickets: a case series in a family

6 citations , January 2014 in “Journal of pediatric endocrinology & metabolism/Journal of pediatric endocrinology and metabolism”

Three siblings with a genetic form of rickets showed different symptoms of the disease.

research Diuretics

1 citations , January 2018 in “Side effects of drugs annual”

Diuretics can cause serious side effects and should be used carefully.

research Assessment of the Ability of the ChatGPT-5 Model to Pass the Endocrinology Specialization Exam

1 citations , September 2025 in “Cureus”

ChatGPT-5 can pass the endocrinology exam but isn't fully reliable for clinical decisions yet.

research Cutaneous Manifestations of Chronic Kidney Disease: A Narrative Review

January 2026 in “Journal of Biosciences and Medicines”

Chronic kidney disease can cause skin issues that need early recognition and combined treatment for better outcomes.

General Dermatology: Comprehensive Overview of Dermatological Conditions

research General Dermatology

January 2017 in “Springer eBooks”

The document explains various skin conditions and their treatments.

research Calcitriol-Resistant Rickets With Alopecia

55 citations , May 1985 in “Archives of Dermatology”

Calcitriol-resistant rickets is an inherited disorder that affects hair growth and causes hair loss.

research Clinical uses for calciotropic hormones 1,25-dihydroxyvitamin D3 and parathyroid hormone-related peptide in dermatology: a new perspective.

23 citations , April 1996 in “PubMed”

Vitamin D3 and parathyroid hormone-related peptide may have important uses in skin treatments.

research Calcitriol-resistant rickets with alopecia

11 citations , May 1985 in “Archives of Dermatology”

Calcitriol-resistant rickets is an inherited disorder that affects hair growth and causes hair loss.

research A phase I safety study of topical calcitriol (BPM 31543) for the prevention of chemotherapy-induced alopecia (CIA).

1 citations , May 2017 in “Journal of Clinical Oncology”

Topical calcitriol is safe for preventing hair loss during chemotherapy.

research Reduction of Intrafollicular Apoptosis in Chemotherapy-Induced Alopecia by Topical Calcitriol-Analogs

53 citations , October 1998 in “The journal of investigative dermatology/Journal of investigative dermatology”

Topical calcitriol-analogs can reduce hair loss caused by chemotherapy.

research Oral calcitriol in the treatment of scleroderma 'en coupe de sabre'

3 citations , January 2000 in “Journal of Dermatological Treatment”

Oral calcitriol helped improve scleroderma and hair regrowth in a young woman.

research Safety, tolerability, and PK of topical calcitriol formulation for treatment of chemotherapy-induced alopecia (CIA) in patients receiving taxane-based regimen: Final results.

May 2019 in “Journal of clinical oncology”

Topical calcitriol was safe and well-tolerated for potential hair loss prevention in chemotherapy patients.

research Calcitriol ointment in the treatment of facial, hairline and retroauricular chronic plaque psoriasis

3 citations , January 1996 in “Journal of Dermatological Treatment”

The ointment is a safe, effective, and well-tolerated treatment for certain types of psoriasis.

research A mechanism for topical cutaneous calcinosis

2 citations , December 1973 in “Calcified tissue research”

Epilation and DHT cause skin calcification by increasing ATP and calcium deposits.

A Phase I Safety Study of Topical Calcitriol (BPM31543) for the Prevention of Chemotherapy-Induced Alopecia: Final Study Results

research A phase I safety study of topical calcitriol (BPM31543) for the prevention of chemotherapy-induced alopecia (CIA): Final study results

October 2018 in “Annals of oncology”

Topical calcitriol (BPM31543) is safe for preventing hair loss from chemotherapy and shows some effectiveness.

research Combination Therapy for Extensive Tumoral Calcinosis in Juvenile Dermatomyositis

February 2026 in “International Journal of Clinical Dermatology”

A multi-drug treatment can effectively clear extensive calcinosis in juvenile dermatomyositis.

research Topical calcitriol (BPM31543) for the prevention of chemotherapy-induced alopecia (CIA): Efficacy findings from a phase I safety study.

2 citations , May 2016 in “Journal of Clinical Oncology”

Topical calcitriol may reduce hair loss from chemotherapy at higher doses.

research Anticonvulsant hypocalcaemia.

July 1972 in “The BMJ”

Long-term use of seizure medications can disrupt calcium metabolism, but this can be treated with vitamin D or UV light and does not affect seizure control.

Experience of Intravenous Calcium Treatment and Long-Term Responses to Treatment in a Patient with Hereditary Vitamin D-Resistant Rickets Resulting from a Novel Mutation

research Experience of intravenous calcium treatment and long-term responses to treatment in a patient with hereditary vitamin D-resistant rickets resulting from a novel mutation

1 citations , May 2019 in “Journal of pediatric endocrinology & metabolism/Journal of pediatric endocrinology and metabolism”

Intravenous calcium therapy is a safe and effective treatment for a rare type of rickets.

research Normalization of Mineral Ion Homeostasis by Dietary Means Prevents Hyperparathyroidism, Rickets, and Osteomalacia, But Not Alopecia in Vitamin D Receptor-Ablated Mice

119 citations , October 1998 in “Endocrinology”

Diet can prevent bone issues but not hair loss in mice lacking vitamin D receptors.

research Calcium in Root Hair Growth

17 citations , January 2009 in “Plant cell monographs”

research Calcium in Root Hair Growth

5 citations , January 2000