Search

everythingexperts & clinicslearnresearchcommunity

for

Search:↓

A 77-year-old woman with metastatic cutaneous squamous cell carcinoma (cSCC) was treated with cemiplimab, an immune checkpoint inhibitor, and achieved a complete clinical and radiological response after eight infusions and local radiation therapy. Following the discontinuation of cemiplimab, she developed alopecia areata (AA) and fingernail dystrophy, which were successfully treated with prednisone and topical corticosteroids, resulting in complete hair regrowth and nail improvement. This case highlights AA as a rare immune-related adverse event associated with cemiplimab, likely due to the breakdown of the hair follicle's immune privilege triggered by the enhanced immune response from the treatment. At a 2-year follow-up, the patient maintained a complete oncologic response.

The document discusses the use of smartphone applications and affordable trichoscopy instruments to enhance teletrichoscopy, allowing for remote evaluation of hair and scalp conditions. It includes detailed descriptions of various hair and scalp disorders, such as hairline recession, alopecia areata, telogen effluvium, lichen planopilaris (LPP), scalp psoriasis, and loose anagen hair, using images captured with micro lenses and microscopes. These images help in diagnosing conditions by highlighting specific features like vellus hairs, yellow and black dots, regrowing hairs, peripilar casts, thick scales, and anagen hairs without sheaths. The document emphasizes the potential of teletrichoscopy in diagnosing and managing hair disorders remotely, with some diagnoses confirmed through in-person follow-ups.