research Comparison of intralesional triamcinolone acetonide alone and with 5 -fluorouracil for the treatment of keloids
Combining TCA with 5-FU is more effective and safer for treating keloids than TCA alone.
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research Efficacy of Betamethasone Oral Mini-Pulse Therapy in the Treatment of Lichen Planus
Betamethasone oral mini-pulse therapy showed good or fair results in treating lichen planus.
research [Low dosage retinol and L-cystine combination improve alopecia of the diffuse type following long-term oral administration].
Retinol and L-cystine improve diffuse hair loss without side effects.
research Retrospective Analysis of Systemic Corticosteroids for Alopecia Areata in Pediatric Patients
Systemic steroids temporarily improve severe alopecia areata in children but often lead to relapse.
research Logic-based modeling and drug repurposing for the prediction of novel therapeutic targets and combination regimens against E2F1-driven melanoma progression
Tadalafil and Finasteride may help treat aggressive melanoma.
research Cyproterone acetate as initial treatment and maintenance therapy for hirsutism
Cyproterone acetate is effective for treating hirsutism, but some patients may feel worse on low-dose maintenance therapy.
research Safety profile of CAP7.1 obtained during Phase I Trial in adult patients with refractory malignancies
CAP7.1 is generally safe at 200 mg/m²/day, but can cause fatigue, nausea, hair loss, fever, and blood-related issues.
research In silico investigation of possible multi-target drugs against Glutamate S-transferase and prolyl tRNA synthetase in Onchocerca volvulus
This study investigates potential multi-target drugs against Onchocerca volvulus, a major cause of blindness in developing regions. Using molecular docking simulations, 2,015 approved drugs were screened against glutamate S-transferase and prolyl tRNA synthetase. Bedaquiline and Telmisartan showed the strongest binding affinities, while Diosmin, Azelastine, and Adapalene were identified as promising multi-target drugs based on molecular dynamics. Other compounds like Drospirenone, Alectinib, Dutasteride, and Finasteride also showed potential. The study suggests repurposing these drugs could offer effective treatments for onchocerciasis, with further validation needed.
research Patent Evaluation: Δ-4,6-Steroids as Potent 5α-Reductase Inhibitors
New steroids were patented as effective for treating acne, hair loss, and other conditions related to hormones.
research LB1048 Effectiveness of OR-101 in a murine model of atopic dermatitis
OR101 may effectively treat atopic dermatitis and similar skin conditions.
research A nanocomposite competent to overcome solubility and permeation issues of capsaicin and thiocolchicoside simultaneously in gout management: Fabrication of nanocubosomes
The new delivery system could improve pain and inflammation relief in gout.
research Treatment of Alopecia Totalis
Higher doses of prednisone and triamcinolone acetonide successfully treated 8 out of 10 alopecia totalis patients.
research Use of a Sustained Release Preparation of Clotrimazole to Treat Dermatophytosis in a Siamang (Hylobates syndactylus)
A special clotrimazole varnish cured a siamang's persistent skin infection after 3 months.
research Caffeic acid N-[3,5-bis(trifluoromethyl)phenyl] amide as a non-steroidal inhibitor for steroid 5α-reductase type 1 using a human keratinocyte cell-based assay and molecular dynamics
Compound 4 is a promising treatment for hair loss with low toxicity.
research DEVELOPMENT OF THE EMULGE LFOR THE ANDROGENIC ALOPECIA TREATMENT
The emulgel with specific ingredients was effective for treating hair loss.
research Betamethasone valerate/minoxidil/tretinoin
The combination of tretinoin, minoxidil, and betamethasone valerate may cause severe scalp inflammation.
research Experimental medication of equine ringworm due to Trichophyton equinum var. autotrophkum
Some treatments worked for horse ringworm, but mass treatment should focus on stopping infection spread, not just hair regrowth.
research Therapeutic Effect of Superficial Cryotherapy versus Intralesional Corticosteroids injection in Alopecia Areata
TCA injections are more effective and safer than cryotherapy for treating alopecia areata.
research A combined regimen of cyproterone acetate and testosterone enanthate as a potentially highly effective male contraceptive.
The combination of cyproterone acetate and testosterone enanthate is highly effective in preventing sperm production and could be a good reversible male contraceptive.
research Dupilumab‐associated cutaneous adverse events among adult patients with atopic dermatitis: A retrospective study
Dupilumab for atopic dermatitis can cause mild skin issues in some patients.
research A New Strategy for Consumption of Functional Lipids from Ericerus pela (Chavannes): Study on Microcapsules and Effervescent Tablets Containing Insect Wax–Derived Policosanol
Microcapsules and effervescent tablets make insect lipids easier to consume.
research Successful Treatment of Cutaneous Mast Cell Tumors in Cats Using Electrochemotherapy: A Case Series
Electrochemotherapy successfully treated skin tumors in cats without recurrence.
research Effect of Citral on Experimentally-induced Comedones
1% citral is more effective for treating comedone acne than salicylic acid.
research Transdermal permeation of tetracaine hydrochloride by lecithin microemulsion: In vivo
Lecithin microemulsion safely delivers tetracaine hydrochloride through the skin.
research Formulation optimization, in vitro and in vivo evaluation of niosomal nanocarriers for enhanced topical delivery of cetirizine
Niosomes can effectively deliver cetirizine topically for treating alopecia.
research Formulation and Physicochemical Characterization of a Nanostructured Lipid Carrier (NLC) Gel Combining Minoxidil and Finasteride for the Treatment of Alopecia in Prospective Hajj Pilgrims
The NLC gel with Minoxidil and Finasteride effectively treats hair loss in harsh conditions.
research Optimasi formula krim hair loss ekstrak saw palmetto [Serenoa repens] dengan humectant gliserol dan sorbital : aplikasi desain faktorial
Saw palmetto cream for hair loss works better with glycerol and sorbitol.
research Hypertrichosis and topical corticosteroid use
Prolonged use of topical corticosteroids can cause excessive hair growth.
research Constructing transnational divas: Gendered production of Balkan Turbo-folk music
Switching to a twice-weekly betamethasone treatment led to full hair regrowth in alopecia areata without side effects.
research Comparative Evaluation of Superficial Cryotherapy vs Intralesional Triamcinolone in Alopecia Areata at a Tertiary Care Center: A Dermoscopic and Clinical Study in Middle-aged Adults
Intralesional triamcinolone is more effective than cryotherapy for treating alopecia areata in middle-aged adults.