April 2023 in “Journal of Investigative Dermatology” Covering a wound can stop hair growth by promoting scarring, but boosting a process called Wnt signaling can help hair grow back even when the wound is covered.
Nod factor can trigger changes in legume root hairs with just one molecule.
41 citations
,
October 2008 in “The American journal of pathology” Blocking a specific protein signal can make hair grow on mouse nipples.
220 citations
,
August 2007 in “Journal of Bone and Mineral Research” Wnt signaling is crucial for bone regeneration.
74 citations
,
April 2024 in “Cell Communication and Signaling” Targeting Wnt/β-catenin signaling can improve healing in chronic wounds.
56 citations
,
April 2019 in “The Plant Journal” Cyclic nucleotide-gated channels are crucial for proper root hair growth and calcium balance in plants.
Understanding wound healing and signaling pathways could lead to new alopecia treatments.
December 2024 in “European journal of medical research” April 2026 in “Development” Hemidesmosomes and Notch signaling help skin cells mature by moving them to the outer layer.
11 citations
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September 2011 in “Biochemical journal” Neurotrophin-4 increases calcium current in specific mouse neurons through the PI3K pathway.
211 citations
,
October 2001 in “The FASEB Journal” Noggin is necessary to start the hair growth phase in skin after birth.
21 citations
,
October 2013 in “Molecular Biology of the Cell” The protein CCN2 controls hair growth by affecting hair follicle formation and stem cell activity in mice.
146 citations
,
February 2012 in “Journal of Clinical Investigation” Blocking Hedgehog signaling offers new treatment options for advanced basal cell carcinoma.
4 citations
,
February 2008 in “Cell stem cell” NFATc1 is crucial for keeping hair follicle stem cells inactive.
July 2025 in “Journal of Investigative Dermatology” TGF-β signaling is essential for hair follicle regeneration during wound healing.
Activating a specific cell pathway helps hair growth and skin healing in mice.
October 2025 in “Cell Death and Disease” CD271 is crucial for maintaining healthy skin and preventing inflammation.
February 2023 in “PubMed” The Wnt/β-catenin signaling pathway is important for skin wound healing and affects inflammation, cell growth, and other healing processes.
December 2017 in “bioRxiv (Cold Spring Harbor Laboratory)” Endoglin is important for proper hair growth cycles and stem cell activation in hair follicles.
Nail stem cells help nail and finger regeneration through BMP signaling.
70 citations
,
December 2004 in “Proceedings of the National Academy of Sciences” BMP signaling affects hair color by interacting with the MC-1R pathway.
27 citations
,
June 2013 in “Genes & development” Cav1.2 affects hair growth and could be a target for hair loss treatments.
January 2025 in “eScholarship@McGill (McGill)” Jag2 is essential for proper skin cell differentiation and organization.
March 2026 in “JID Innovations” Aire mutation reduces alopecia areata, while Notch4 mutation prevents it in mice.
October 2005 in “Nature reviews. Molecular cell biology (Print)” Hairless protein is key for hair growth, cell differences cause gene expression variation, and the N-end rule pathway senses nitric oxide for protein breakdown.
Pvalb8 is essential for zebrafish hearing and hair cell development, and its mutation causes hearing loss.
91 citations
,
December 2019 in “The EMBO Journal” NEDD4 and NEDD4L help control intestinal stem cells and prevent tumors by breaking down the LGR5 receptor.
159 citations
,
January 2006 in “BMC Cell Biology” Wnt signaling can improve skin healing by promoting epithelial growth.
September 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” FOL-026 peptide can help repair blood vessels and promote growth, offering potential treatment for vascular diseases.