October 2017 in “The Japanese Biochemical Society/The Molecular Biology Society of Japan” Some natural compounds might help hair grow.
December 2014 in “Turk Dermatoloji Dergisi” Topical Saw Palmetto and Trichogen Veg Complex increased hair count by 11.9% and improved hair growth in 48% of men with hair loss.
August 2024 in “Clinical Cosmetic and Investigational Dermatology” Ixekizumab effectively treated severe psoriasis and hair loss in a patient.
2 citations
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May 2020 in “Journal of the American Academy of Dermatology” Hair shaft changes may be linked to CCCA, but their role is unclear.
Niosomes improve aminexil's effectiveness in preventing hair loss without needing propylene glycol.
Polygonum multiflorum may help treat hair loss but can be toxic to the liver.
June 2010 in “Melanoma research” LDE225 is a promising skin-applied treatment for basal cell carcinoma with good skin penetration and effectiveness.
November 2025 in “Journal of Nanobiotechnology” A new treatment using special nanovesicles with linoleic acid shows promise in improving hair growth and reducing irritation for hair loss.
Chitosan, a cationic polysaccharide, shows promise in aesthetic dermatology for skin barrier support, post-procedure recovery, acne, pigmentary disorders, and scalp applications. Clinical studies indicate that chitosan hydrogels aid recovery after laser treatments and enhance the performance of topical actives like nicotinamide in acne and melasma. In scalp applications, microneedling with topical chitosan improved hair density similarly to minoxidil in small studies. Despite its potential, the variability in formulations and small study sizes limit the generalizability of these findings, highlighting the need for larger, standardized clinical trials to better define chitosan's role in aesthetic practices.
3 citations
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April 2022 in “International Journal of Molecular Sciences” Scientists turned mouse skin cells into hair-inducing cells using chemicals, which could help treat hair loss.
1 citations
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January 2024 in “Egyptian Dental Journal /Egyptian Dental Journal” The combined treatment improves lip texture, elasticity, and firmness for up to nine months.
13 citations
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September 2012 in “Cell & tissue research/Cell and tissue research” pCLCA2 protein may help maintain skin structure and function.
5 citations
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September 2024 in “Biomolecules and Biomedicine” Total glucosides of paeony may help treat alopecia areata by reducing inflammation and hair loss.
January 2026 in “Zenodo (CERN European Organization for Nuclear Research)” LX-38 is a safer drug option for hair loss and prostate issues without hormonal side effects.
January 2026 in “Applied Biological Chemistry” Ishophloroglucin A from Ishige okamurae may be a natural alternative for treating hair loss by inhibiting 5α-reductase and promoting hair growth.
5 citations
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July 2019 in “Investigational new drugs” TLR7-based compounds may help manage chemotherapy-induced hair loss.
October 2025 in “Pharmaceutical Development and Technology” Cubosomal gels enhance skin absorption of cetirizine better than niosomal gels.
Platelet-derived extracellular vesicles can boost hair growth by activating a specific signaling pathway.
28 citations
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March 2017 in “Scientific Reports” Minoxidil may protect nerves and improve hair quality during paclitaxel treatment.
February 2024 in “Journal of cutaneous and aesthetic surgery” The combined treatment helps improve severe hair loss and reduces the need for other medications.
May 2023 in “Journal of Endocrinology and Reproduction” Blocking cholesterol production may help control hair loss in Primary Cicatricial Alopecia by affecting key regulators.
19 citations
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December 2015 in “Journal of Materials Chemistry B” Scientists have created a method to deliver specific cells that can regenerate hair follicles, potentially offering a new treatment for hair loss.
September 2023 in “Journal of the American Academy of Dermatology” CTP-543 significantly improved eyebrow and eyelash regrowth and patient satisfaction in adults with alopecia areata.
February 2026 in “Biomedicine & Pharmacotherapy” MLPH helps hair grow by activating IGF-1 signaling in hair cells.
The PI's development is closely linked to skin and hair pigmentation in macaques.
6 citations
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November 2019 in “Journal of Cosmetic Dermatology” The compound improved hair growth and reduced hair loss.
8 citations
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September 2017 in “Journal of Investigative Dermatology” CXXC5 is a protein that prevents hair growth and could be a target for hair loss treatment.
April 2023 in “Advances in Natural Sciences: Nanoscience and Nanotechnology” The new formulation with minoxidil, chitosan, and Aloe vera improves hair growth and reduces side effects.
1 citations
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December 2007 in “Journal of Microbiology and Biotechnology” Minoxidil in triamino alpha-cyclodextrin promotes hair growth effectively.
February 2017 in “Medicina cutánea ibero-latino-americana” An 8-year-old boy with hair loss had hair regrowth and responded well to clobetasol propionate treatment.