391 citations
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September 2015 in “Journal of Clinical Lipidology” The guidelines suggest lifestyle changes, diet adjustments, and personalized medication to manage dyslipidemia and reduce heart disease risk.
370 citations
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September 1999 in “The New England Journal of Medicine” Finasteride and minoxidil are effective for hair loss, but continued research is needed for better treatments.
249 citations
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November 2003 in “Clinical endocrinology” Insulin resistance is a key factor in polycystic ovary syndrome, but genetics may also contribute.
218 citations
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April 2012 in “British Journal of Dermatology” Guidelines suggest various treatments for alopecia areata, but leaving it untreated is also an option as 80% cases may recover on their own.
157 citations
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August 2010 in “Lupus” The document concludes that recognizing and treating cutaneous lupus erythematosus early is crucial for managing the skin and potential systemic symptoms.
142 citations
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December 1991 in “Antimicrobial Agents and Chemotherapy” Dextran sulfate was found to be toxic and ineffective for treating HIV.
137 citations
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March 2006 in “Cns Drug Reviews” Finasteride treats enlarged prostate and hair loss, but may cause side effects in some patients.
127 citations
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June 2008 in “British Journal of Clinical Pharmacology” Low doses of some substances can be beneficial, while high doses can be harmful or toxic.
126 citations
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April 2015 in “Clinical, cosmetic and investigational dermatology” Choosing the right patients, using proper techniques, and having thorough knowledge are key to preventing and managing dermal filler complications.
117 citations
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August 2008 in “Sociology of Health and Illness” The conclusion is that the increasing use of drugs for lifestyle reasons is a complex issue influenced by corporate profit, consumer behavior, and the medicalization of everyday life, with potential negative effects on personal well-being.
117 citations
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February 2017 in “American Journal of Clinical Dermatology” Oral spironolactone's effectiveness for adult female acne is not well-supported by strong evidence.
103 citations
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January 2011 in “Blood” Thymus transplantation successfully restored immune function in infants with FOXN1 deficiency.
94 citations
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July 2020 in “European Journal of Human Genetics” The guidelines ensure accurate genetic testing and reporting for 21-hydroxylase deficiency.
80 citations
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June 2020 in “Dermatopathology” COVID-19 can cause various skin lesions, which may result from the virus and immune response, and are not directly linked to illness severity.
77 citations
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June 2015 in “Nature Reviews Urology” Some common medications can harm male fertility, but many effects can be reversed.
75 citations
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January 2014 in “Archiv Der Pharmazie” Jasmonic acid and its derivatives play important roles in plant health and have potential uses in medicine and agriculture.
64 citations
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July 2011 in “Dermatologic Therapy” Scalp cooling can prevent chemotherapy-induced hair loss, and certain treatments can speed up hair regrowth, but more research is needed for better treatments.
62 citations
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May 1997 in “Journal of Pharmaceutical Sciences” Sebaceous glands in the skin play a key role in absorbing the antiandrogen drug RU 58841, especially when it's encapsulated in liposomes.
59 citations
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June 2008 in “Journal of The American Academy of Dermatology” The article explains the genetic causes and symptoms of various hair disorders and highlights the need for more research to find treatments.
56 citations
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November 2016 in “Aesthetic surgery journal” The document concludes that the effectiveness of platelet rich plasma in aesthetic surgery is unclear due to inconsistent reporting and lack of objective measures in studies.
53 citations
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January 2011 in “Diabetes” People with PCNT mutations often develop severe insulin resistance and early-onset diabetes during childhood or adolescence.
51 citations
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February 2010 in “Analytical and Bioanalytical Chemistry” Researchers developed a method to detect hormone-blocking drugs in wastewater and found them in Beijing's sewage, suggesting they can survive sewage treatment.
51 citations
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October 2002 in “British Journal of Dermatology” Finasteride increases hair density in female androgenetic alopecia, but individual results may vary.
48 citations
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February 2025 in “Nano-Micro Letters” Microneedles offer a promising, painless way to treat skin diseases but need improvements for better use.
45 citations
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February 2005 in “Steroids” Four new compounds were more effective than finasteride in treating prostate issues and hair loss, with one being 100 times more active and safe for use.
44 citations
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July 2011 in “Dermato-endocrinology” Thyroid hormone affects skin health, with too little causing rough, pale skin and too much leading to smooth, thin skin, and may also impact wound healing and skin conditions.
42 citations
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July 2014 in “Journal of biological chemistry/The Journal of biological chemistry” Heparan sulfate is important for hair growth, preventing new hair formation in mature skin, and controlling oil gland development.
38 citations
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June 2005 in “Contact Dermatitis” Patient had scalp allergy from minoxidil; test helped identify cause and suggest alternative treatments.
37 citations
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October 2006 in “Steroids” New sulfur-containing steroid analogs show promise for more targeted medical treatments.
36 citations
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October 2022 in “ULTRASONOGRAPHY” Ultrasonography in dermatology improves diagnosis and treatment of skin conditions.