25 citations
,
January 2019 in “British Journal of Dermatology” Low oxygen levels can make hair-growing cells better at growing hair through a process involving reactive oxygen species.
December 2025 in “Scientific Reports” α-Mangostin can naturally lighten skin by reducing melanin.
56 citations
,
December 2010 in “The journal of investigative dermatology/Journal of investigative dermatology” Hair follicle cells age faster and lose pigment due to less catalase, causing hair to turn gray.
3 citations
,
October 2023 in “Cosmetics” Effervescent cleansing tablets with Asiatic acid were successfully developed, showing good stability and cleansing effectiveness.
2 citations
,
January 2015 July 2024 in “Journal of Investigative Dermatology” PP405 may help hair growth by activating hair follicle stem cells.
9 citations
,
March 2019 in “Molecular & cellular proteomics” Reductive stress messes up collagen balance and alters cell signaling in human skin cells, which could help treat certain skin diseases.
2 citations
,
August 2024 in “Indian Dermatology Online Journal” Premature graying of hair is mainly caused by genetics, stress, and environment, with potential treatments being explored.
January 2026 in “International Journal of Dermatology Venereology and Leprosy Sciences” Metformin may improve acanthosis nigricans by reducing insulin resistance.
18 citations
,
December 2016 in “European journal of pharmacology” A new compound slows cancer cell growth and causes cell death by blocking cell cycle progression and increasing cell-damaging molecules.
June 2021 in “Clinical neuropsychopharmacology and therapeutics” Valproic acid can cause hair color change in older men.
1 citations
,
December 2021 in “Daehan hwa'sang haghoeji” A patient with a severe scalp burn developed chronic bone infection, treated with surgery and muscle-skin flap from the back.
26 citations
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July 2007 in “Biochemical Pharmacology” ISCK03 stops melanin production in human melanoma cells and lightens skin color in mice and guinea pigs.
1 citations
,
March 2004 in “Patty's Toxicology” These chemicals can be toxic and cause health issues like irritation, liver damage, and cancer.
15 citations
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June 1993 in “Archives of Dermatology” A 22-year-old's gray hair partially turned back to its original color without known causes.
December 2017 in “JURNAL FARMANESIA” Red dragon fruit peel extract can effectively dye gray hair black.
45 citations
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June 2013 in “Burns” Treatments for burn wounds in rats should be timed according to whether autophagy or apoptosis is more active at certain times after the burn.
24 citations
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January 2023 in “Cancer Research” AMPK activation may reduce melanoma risk in red-haired individuals.
Stiffness gradients in alginate gels can guide cancer cell invasion and study cellular behaviors.
1 citations
,
September 2008 in “International Journal of Cosmetic Science” Using chelants in hair dye reduces fiber damage by preventing harmful radicals.
1 citations
,
May 2025 in “International Journal of Applied Pharmaceutics” The nanogel with Bangkal bark extract effectively fights acne-causing bacteria.
12 citations
,
May 2019 in “Journal of cosmetic dermatology” Effective treatments for premature hair graying still require significant research.
8 citations
,
August 1993 in “Colloid & Polymer Science” The observed "toughening" in keratin was actually due to water evaporation, not a real change in keratin.
6 citations
,
September 2024 in “BMC Pulmonary Medicine” Cepharanthine may help treat lung fibrosis by affecting certain immune cells.
The treatment showed limited success in repigmenting hair for vitiligo-associated leukotrichia.
26 citations
,
January 2018 in “Annals of dermatology/Annals of Dermatology” Hair graying may be caused by stem cell depletion from stress or melanocyte damage.
13 citations
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March 2010 in “International Journal of Cosmetic Science” Hair coloring increases copper and calcium uptake, damaging hair and reducing shine.
3 citations
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October 2021 in “Cureus” Smoking can cause yellow discoloration of upper lip hair and nails.
Ancient herders in the Keriya Valley fed their animals mainly C3 plants, with some C4 plant feeding possibly due to herd movement or seasonal changes.
8 citations
,
October 2022 in “International Journal of Molecular Sciences” The hydrogels improved healing in deep second-degree burns.