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The document concludes that biotin, folate, and RGD peptides are promising for targeting cancer cells with prodrugs, but the conjugates are not yet tested for use.

ACBP is crucial for healthy skin in mice.

Long-lived proteins may predict age-related diseases.

This enzyme helps metabolize fatty acids and isoleucine, and could be key in treating neurological diseases and certain cancers.

Mouse high-glycine/tyrosine proteins have distinct patterns in hair follicles, peaking at specific hair cycle days.

The ketogenic diet can worsen biotin deficiency, suggesting a need for biotin supplements.

High temperatures and certain chemicals can significantly change the amino acid content in human hair.

Reptile skin hardens by layering beta-proteins on keratin.

A new method speeds up insulin amyloid fibril growth, useful for studying diseases.

A protein called CBP is found in prostate cancer and can increase the effectiveness of certain prostate cancer treatments.

Citrullinated proteins from Porphyromonas gingivalis may contribute to rheumatoid arthritis.

Free fatty acids may increase androgen production, potentially contributing to polycystic ovary syndrome.

Targeting ornithine decarboxylase can help prevent skin cancer.

Different keratins have unique expression patterns in mouse skin cells.

The protein structures in the hair and tendon were preserved, but their molecular arrangements changed.

Trichohyalin is modified by enzymes to form strong structures in hair cells.

Alkylation of human hair keratin allows for adjustable drug release rates in hydrogels for medical use.

A specific type II hair keratin was identified and found in hair cortex and tongue cells.

Two genetic disorders affect biotin metabolism, causing severe skin, hair, and metabolic issues.

PCOS has three subtypes, with 11-oxygenated androgens increasing metabolic risk.

Mutations in the SRD5A3 gene cause a new type of glycosylation disorder by blocking the production of a molecule necessary for protein glycosylation.

Nitrogen starvation in microalgae increases lipid production, making it a potential biofuel source.

Cyproterone acetate may cause liver cancer at high doses, but is considered safe at recommended doses for approved uses.

CCCA may be a fibroproliferative disorder, and anti-fibrotic therapies could help.

Autophagy is important for determining the protein makeup of hair.

Pure carbon nanotubes are safe for mice, but impure ones cause immune issues and hair loss.

PROTACs show promise in cancer treatment by effectively degrading specific harmful proteins.

Newly designed proteins can effectively degrade specific proteins in cells, offering a potential new therapy method.