research Keratin disorders: from gene to therapy
New treatments targeting specific genes show promise for treating keratin disorders.
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210-240 / 1000+ results research 0749 Serine and arginine-rich splicing factor 3 regulates epidermal differentiation in cutaneous squamous cell carcinoma
research The Proteins of Normal and Aberrant Hair Keratins
Hair is mostly made of three protein types: helical, high-sulfur, and high-tyrosine.
research Thiadiazole chitosan conjugates as a novel cosmetic ingredient for rinse-off hair conditioners: design, formulation, characterization and in silico-molecular docking studies
Thiadiazole chitosan conjugates improve hair manageability, moisture, and protection in conditioners.
research Analysis of the abnormal human hair keratins by two-dimensional polyacrylamide gel electrophoresis
research Epidermal cyst containing numerous spherules of keratin
The cyst had unusual keratin spherules and resembled bone marrow.
research Structural Transition of Trichocyte Keratin Intermediate Filaments During Development in the Hair Follicle
research De novo filament formation by human hair keratins K85 and K35 follows a filament development pattern distinct from cytokeratin filament networks
Human hair keratins K85 and K35 create unique filament patterns important for early hair formation.
research The presence of glycoproteins in the cell membrane complex of a variety of keratin fibres
Glycoproteins are present in the cell membranes of various keratin fibers.
research Rational design of keratin-based injectable hydrogels for biomedical applications
Keratin-based hydrogels can be improved for medical use by adding PEG, making them more soluble and adjustable.
research Single-Cell Proteomics Uncovers Dual Traits of Dermal Sheath Cells in Wound Repair
Dermal sheath cells help heal wounds by showing both skin and connective tissue traits.
research Biochemical Evidence That Small Proline-rich Proteins and Trichohyalin Function in Epithelia by Modulation of the Biomechanical Properties of Their Cornified Cell Envelopes
Small proline-rich proteins and trichohyalin help make epithelial tissues tougher and more flexible.
research The structure of human trichohyalin : potential multiple roles as a functional ef-hand-like calcium-binding protein, a cornified cell envelope precursor, and an intermediate filament-associated (cross-linking) protein
Trichohyalin is a versatile protein involved in hair and skin structure.
research Ultrastructure of the contrasting types of keratinization seen in the tail epidermis of the laboratory mouseMus musculus
Mouse tail skin has different keratinization near hair follicles and scales.
research Can be Hair-Keratin a Potent Biomaterial?
research Transgenic Kallikrein 14 Mice Display Major Hair Shaft Defects Associated with Desmoglein 3 and 4 Degradation, Abnormal Epidermal Differentiation, and IL-36 Signature
Mice with extra human KLK14 had hair and skin problems, including weaker cell bonds and inflammation, linked to Netherton syndrome.
research Case Report: Bi-allelic missense variant in the desmocollin 3 gene causes hypotrichosis and recurrent skin vesicles
A new genetic change in the DSC3 gene is linked to a rare condition causing hair loss and skin blisters in a child.
research Biochemistry of Transglutaminases and Cross-Linking in the Skin
research 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) Affects Keratin 1 and Keratin 17 Gene Expression and Differentially Induces Keratinization in Hairless Mouse Skin
research Preparation and characterization of keratin-based biocomposite hydrogels prepared by electron beam irradiation
Keratin-based hydrogels from human hair and wool are promising for wound dressings and are more eco-friendly.
research A Congenital Hair Defect: Trichoschisis With Alternating Birefringence and Low Sulfur Content
research Single-cell transcriptomics defines keratinocyte differentiation in avian scutate scales
The research identified two types of keratinocytes in chicken scales: one for hard scales and another for soft skin, with similarities to human skin differentiation.
research Keratin biomaterials for wound healing and tissue regeneration: A promising approach in biomedical applications
Keratin biomaterials could help heal wounds and regenerate tissue, but more testing is needed.
research A highly resistant structure between the cuticle and the cortex of human hair. II . CARB , a penetration barrier
CARB is a strong barrier in human hair that prevents dye penetration.
research Mycobacterial 65,000 MW heat-shock protein shares a carboxy-terminal epitope with human epidermal cytokeratin 1/2.
A mycobacterial protein shares a similar region with a human skin protein, possibly affecting skin diseases.
research Intercellular junctions in normal epidermis
Desmosomal adhesion is essential for healthy skin structure and function.
research Keratins as an Inflammation Trigger Point in Epidermolysis Bullosa Simplex
Mutant keratins cause inflammation in Epidermolysis Bullosa Simplex, suggesting targeting them could help treat the disorder.
research Strategies for improved hair binding: Keratin fractions and the impact of cationic substructures
Certain treatments can increase protein binding to natural hair but are less effective on permed hair.
research Chemical modification of keratin fibers using 2‐iminothiorane hydrochloride
2-iminothiorane hydrochloride improves hair waving permanence without damage.