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GlossaryCarcinomas

Carcinomas are a type of cancer that originates in epithelial cells, which line the surfaces of organs and structures throughout the body. While not directly related to hair loss, certain carcinomas, particularly those affecting the scalp or skin, can lead to hair loss due to localized treatments like radiation or surgical removal. Additionally, some systemic treatments for cancer, such as chemotherapy, can cause widespread hair thinning or loss as a side effect. Understanding carcinomas is important in the context of hair biology, as they can impact the health of hair follicles and the scalp environment.

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research Transgenic mice overexpressing protein kinase C epsilon in their epidermis exhibit reduced papilloma burden but enhanced carcinoma formation after tumor promotion.

99 citations , February 2000 in “PubMed”

Overexpressing PKCepsilon in mice reduces papillomas but increases carcinomas.

research Zinc Content of Hair from the Head of Carcinoma Patients

13 citations , March 1962 in “Nature”

Carcinoma patients may have lower zinc levels in their hair.

Androgen Receptor Gene Polymorphism (SNP RS6152) – Its Relationship to Androgen-Sensitive Genes Expression in Benign Prostatic Hyperplasia, Carcinoma of the Prostate, and Androgenetic Alopecia

research 409 ANDROGEN RECEPTOR GENE POLYMORPHISM (SNP RS6152) – ITS RELATIONSHIP TO ANDROGEN-SENSITIVE GENES EXPRESSION IN BENIGN PROSTATIC HYPERPLASIA, CARCINOMA OF THE PROSTATE AND ANDROGENETIC ALOPECIA

March 2011 in “European Urology Supplements”

Gene variation affects prostate issues and hair loss.

research Trichoblastic Carcinoma (“Malignant Trichoblastoma”) with Lymphatic and Hematogenous Metastases

80 citations , June 2000 in “Modern Pathology”

Long-standing benign tumors can become cancerous, especially in people with weakened immune systems.

research Immunohistochemical demonstration of breast‐derived and/or carcinoma‐associated glycoproteins in normal skin appendages and their tumors

71 citations , February 1992 in “Journal of Cutaneous Pathology”

Antibodies help identify glycoproteins in normal skin and tumor cells.

research Resolution of paraneoplastic alopecia following surgical removal of a pancreatic carcinoma in a cat

52 citations , January 1999 in “Journal of Small Animal Practice”

Removing a cat's pancreatic cancer can temporarily reverse hair loss caused by the disease.

research Increased lactate dehydrogenase activity is dispensable in squamous carcinoma cells of origin

36 citations , January 2019 in “Nature communications”

High lactate dehydrogenase activity is not necessary for the growth of squamous cell carcinoma.

research The molecular pathogenesis of Trichilemmal carcinoma

19 citations , June 2020 in “BMC Cancer”

Trichilemmal carcinoma shares genetic changes with other skin cancers, suggesting similar causes and potential treatments.

research Pilomatrix Carcinoma: Report of Two Cases of the Head and Review of the Literature

12 citations , January 2023 in “Current Oncology”

Early detection and complete surgical removal are crucial for better outcomes in treating pilomatrix carcinoma.

research Application and Progress of Cultured Models of Gallbladder Carcinoma

8 citations , January 2023 in “Journal of Clinical and Translational Hepatology”

Advancements in cultured models improve understanding and treatment of gallbladder cancer.

research Sebaceous carcinoma arising at a chronic candidiasis skin lesion of a patient with keratitis-ichthyosis-deafness (KID) syndrome

6 citations , July 2011 in “British Journal of Dermatology”

A man with KID syndrome developed a rare cancer in a long-term skin infection.

Influence of Sex and Functional Status on the Value of Serum Steroid Profiling in Discriminating Adrenocortical Carcinoma from Adrenocortical Adenoma

research Influence of sex and functional status on the value of serum steroid profiling in discriminating adrenocortical carcinoma from adrenocortical adenoma

4 citations , September 2024 in “Frontiers in Endocrinology”

Serum steroid profiling, especially 11-deoxycortisol, helps distinguish between adrenocortical carcinoma and adenoma, considering sex and functional status.

Feline Paraneoplastic Alopecia Associated with Metastasizing Intestinal Carcinoma

research Feline paraneoplastic alopecia associated with metastasising intestinal carcinoma

4 citations , July 2015 in “Journal of Feline Medicine and Surgery Open Reports”

A cat with hair loss and illness was found to have cancer spread from its colon.

research [ADRENOCORTICAL CARCINOMA].

2 citations , December 2016 in “PubMed”

Adrenocortical carcinoma is a rare, aggressive adrenal gland cancer with a poor outlook.

research A rare case of poorly-differentiated endometrial carcinoma in a female-to-male transgender man on testosterone therapy

1 citations , November 2023 in “American journal of clinical pathology”

Transgender men on testosterone therapy need ongoing gynecologic care due to potential cancer risks.

research Beyond the Matrix: A Rare Case of Pilomatrix Carcinoma with Histologic Insights

January 2026 in “Annals of Pathology and Laboratory Medicine”

Accurate diagnosis of rare pilomatrix carcinoma is crucial for effective treatment.

research Patterns of keratinocyte carcinoma incidence on the scalp and forehead of non-alopecic women: a retrospective review

September 2025 in “Archives of Dermatological Research”

Basal cell carcinoma is more common than squamous cell carcinoma on the scalp, especially along the part line.

research 54622 A characterization of US patients with keratinocyte carcinomas using DataDerm

September 2024 in “Journal of the American Academy of Dermatology”

Most U.S. keratinocyte carcinoma patients are older white males living in urban areas.

Subtle Trichilemmal Carcinoma of Neck Initially Misdiagnosed as Benign Cyst and Ultimately Treated with Mohs Micrographic Surgery

research Subtle Trichilemmal Carcinoma of Neck Initially Misdiagnosed as Benign Cyst and Ultimately Treated with Mohs Micrographic Surgery

November 2023 in “Skin”

A neck lesion misdiagnosed as benign was later treated successfully with Mohs Micrographic Surgery.

research Prostate Carcinoma, what would be the best to do ?

January 2023 in “International Journal of Clinical and Medical Education Research”

Correct testosterone levels for age to treat prostate cancer, using low dose treatments as necessary.

research ODP021 A Feminizing Adrenocortical Carcinoma Presenting with Marie-Antoinette Syndrome

November 2022 in “Journal of the Endocrine Society”

A man's rare adrenal tumor caused feminization and white hair, was removed surgically, and improved after treatment.

A Unique Case of Isolated Dehydroepiandrosterone-Sulfate Secreting Adrenocortical Carcinoma: A Case Report with Review of the Literature

research A Unique Case of Isolated Dehydroepiandrosterone-Sulfate Secreting Adrenocortical Carcinoma: A Case Report with Review of the Literature

October 2021 in “Acta Scientific Medical Sciences”

A woman was diagnosed with a rare adrenal gland cancer that did not show usual hormone-related symptoms.

The Molecular Pathogenesis of Trichilemmal Carcinoma

research Onycholemmal Carcinoma

35 citations , September 2004 in “American Journal of Dermatopathology”

A rare nail bed cancer was successfully treated with no recurrence after 4 years.

research Epidermal hyperplasia and oral carcinoma in mice overexpressing the transcription factor ATF3 in basal epithelial cells

31 citations , February 2007 in “Molecular Carcinogenesis”

Overexpressing ATF3 in mice's epithelial cells may lead to oral cancer.

research Hypothyroidism in Thyroid Carcinoma Follow-up: Orlistat May Inhibit the Absorption of Thyroxine

22 citations , June 2005 in “Clinical Oncology”

Orlistat might block the body's ability to absorb thyroid medication.