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Finasteride Effectively Attenuates the Impairments of Left Ventricular Function and Cardiac Sympathovagal Balance in Both Aging and Obese Male Rats via Reducing Systemic Oxidative Stress

research Finasteride effectively attenuates the impairments of left ventricular function and cardiac sympathovagal balance in both aging and obese male rats via reducing systemic oxidative stress

November 2023 in “European heart journal”

Finasteride improves heart function and balance in aging and obese male rats by reducing oxidative stress.

Inconsistent Effects of Surgical and Chemical Castration on Arterial Baroreceptor Dysfunction and Cardiac and Brainstem Inflammation in Endotoxic Rats

research Inconsistent effects of surgical and chemical castration on arterial baroreceptor dysfunction and cardiac and brainstem inflammation in endotoxic rats

April 2020 in “The FASEB Journal”

Surgical and chemical castration have varied effects on heart and brain inflammation and artery function in sick rats.

research Loss of Repressor Activator Protein 1 Precipitates Cardiac Aging in Mice via p53/PPARα Signaling

April 2020 in “The FASEB Journal”

Loss of Rap1 protein speeds up heart aging in mice.

research Finasteride promotes worsening of the cardiac deleterious effects of nandrolone decanoate and protects against genotoxic and cytotoxic damage

January 2020 in “Brazilian Journal of Pharmaceutical Sciences”

Finasteride worsens heart damage from nandrolone decanoate but protects against cell damage.

research COVID-19 in adult patients with pre-existing chronic cardiac, respiratory and metabolic disease: a critical literature review with clinical recommendations

122 citations , August 2020 in “Tropical Diseases Travel Medicine and Vaccines”

COVID-19 severely affects older adults with chronic heart, lung, or metabolic diseases.

Fibroblast Growth Factor-9 Enhances M2 Macrophage Differentiation and Attenuates Adverse Cardiac Remodeling in the Infarcted Diabetic Heart

research Fibroblast Growth Factor-9 Enhances M2 Macrophage Differentiation and Attenuates Adverse Cardiac Remodeling in the Infarcted Diabetic Heart

44 citations , March 2015 in “PLOS ONE”

Fibroblast Growth Factor-9 (FGF-9) can help improve heart function in diabetic mice after a heart attack by reducing inflammation and harmful changes to the heart's structure.

research Prostaglandin E ₂ Receptor 2 Modulates Macrophage Activity for Cardiac Repair

29 citations , September 2018 in “Journal of the American Heart Association”

EP 2 receptor is essential for heart repair by helping macrophages work properly.

research Loss‐of‐function of Endothelin receptor type A results in Oro‐Oto‐Cardiac syndrome

11 citations , March 2020 in “American Journal of Medical Genetics Part A”

A mutation in the EDNRA gene causes Oro-Oto-Cardiac syndrome, affecting face and heart development.

Effects of Chronic Inhibition of Testosterone Metabolism on Cardiac Remodeling After Ischemia/Reperfusion-Induced Myocardial Damage in Gonadectomized Rats

research Effects of chronic inhibition of Testosterone metabolism on cardiac remodeling after ischemia/reperfusion-induced myocardial damage in gonadectomized rats

4 citations , May 2019 in “Biology open”

Testosterone reduces heart damage and inflammation after injury.

research Genetically engineered biomimetic ATP-responsive nanozyme for the treatment of cardiac fibrosis

2 citations , January 2025 in “Journal of Nanobiotechnology”

A new engineered treatment shows promise in curing heart fibrosis.

research Wnt1/βcatenin injury response activates the epicardium and cardiac fibroblasts to promote cardiac repair: Wnt1/βcatenin injury response regulates cardiac repair

1 citations , November 2020

The Wnt1/βcatenin pathway is crucial for heart repair after injury.

research Metoprolol-spironolactone combination for coronary heart disease with concurrent heart failure: impact on cardiac function

January 2026 in “American Journal of Translational Research”

The metoprolol-spironolactone combination improves heart function in patients with coronary heart disease and heart failure.

research Ion Sequential Therapy Aligned With Pathological Changes Enhances Cardiac Function After Myocardial Infarction

September 2024

Ion sequential therapy improves heart function after a heart attack.

research P50 Difficult to diagnose SLE manifestations associated with cardiac arrest, myocarditis, chronic pericarditis, polyneuropathy

March 2020 in “Poster presentations”

Accurate diagnosis of SLE requires extensive testing due to its complex symptoms.

research Human hair-follicle associated pluripotent (HAP) stem cells differentiate to cardiac muscle cells

April 2017 in “Journal of dermatological science”

Human hair follicles can produce stem cells that turn into heart muscle cells.

research Hair-follicle associated pluripotent (HAP) stem cells differentiate to beating cardiac tissue sheets

September 2016 in “Journal of Dermatological Science”

Hair follicle stem cells can become heart muscle cells.

research Influence of tamsulosin and finasteride on circadian rhythm and cardiac function in male elderly patients with chronic heart failure

January 2014 in “Shiyong laonian yixue”

Tamsulosin and finasteride improve heart function and circadian rhythm in elderly men with heart failure and prostate issues.

research Abstract 153: Inhibition of the 5-a-reductase Reduces Cardiac Hypertrophy and Improves Cardiac Function

August 2013 in “Circulation Research”

Finasteride reduces heart enlargement and improves heart function.

research Long-term storage of follicular units in a patient with acute cardiac symptoms during hair transplantation

July 2013 in “International Society of Hair Restoration Surgery”

Effective storage of hair follicles is crucial for successful hair transplants, especially in patients with heart issues.

Corrigendum to 'Anti-Androgenic Therapy with Finasteride Improves Cardiac Function, Attenuates Remodeling and Reverts Pathologic Gene-Expression After Myocardial Infarction in Mice'

research Corrigendum to “Anti-androgenic therapy with finasteride improves cardiac function, attenuates remodeling and reverts pathologic gene-expression after myocardial infarction in mice” Journal of Molecular and Cellular Cardiology 122 (2018) 114–124

November 2018 in “Journal of Molecular and Cellular Cardiology”

Finasteride improves heart function and repairs damage after heart attack in mice.

Isoproterenol Directs Hair Follicle-Associated Pluripotent (HAP) Stem Cells to Differentiate In Vitro to Cardiac Muscle Cells Which Can Be Induced to Form Beating Heart-Muscle Tissue Sheets

research Isoproterenol directs hair follicle-associated pluripotent (HAP) stem cells to differentiate in vitro to cardiac muscle cells which can be induced to form beating heart-muscle tissue sheets

29 citations , March 2016 in “Cell cycle/Cell cycle (Georgetown, Tex. Online)”

Isoproterenol helps hair follicle stem cells turn into beating heart muscle cells.

research Hypoxia Enhances Differentiation of Hair Follicle-Associated-Pluripotent (HAP) Stem Cells to Cardiac-Muscle Cells

13 citations , September 2016 in “Journal of Cellular Biochemistry”

Low oxygen levels help hair follicle stem cells turn into heart muscle cells faster.

research Towards the Development of AgoKirs: New Pharmacological Activators to Study Kir2.x Channel and Target Cardiac Disease

9 citations , August 2020 in “International Journal of Molecular Sciences”

New compounds may help treat heart disease by activating specific potassium channels.

research 895 Isoproterenol directs human hair follicle-associated pluripotent (hHAP) stem cells to differentiate to cardiac muscle cells

April 2017 in “The journal of investigative dermatology/Journal of investigative dermatology”

Human hair follicles can be used to create heart muscle cells.

research From hair to heart: nestin-expressing hair-follicle-associated pluripotent (HAP) stem cells differentiate to beating cardiac muscle cells

64 citations , May 2015 in “Cell Cycle”

Hair follicle stem cells can become heart muscle cells.

research Early-age-dependent selective decrease of differentiation potential of hair-follicle-associated pluripotent (HAP) stem cells to beating cardiac-muscle cells

6 citations , July 2016 in “Cell cycle/Cell cycle (Georgetown, Tex. Online)”

Younger mice's hair-follicle stem cells are better at turning into heart cells than older mice's.

research A hospital-based study to assess the prevalence of Androgenetic alopecia in young male patients admitted to a Cardiac care unit (2021)

August 2023

The study looked at how common male pattern baldness is in young men in a heart care unit but didn't give specific results.

research Exploring in vitro markers of potency of extracellular vesicles from cardiosphere-derived cells in the treatment of cardiac ageing

October 2022 in “European Heart Journal”

Potent extracellular vesicles from cardiosphere-derived cells can improve heart health and other functions in aging.

research Investigation of the extent of cardiomyocyte regeneration in the injured zebrafish heart and the role of Wnt signaling during cardiac repair

January 2018 in “OPen Access Repositorium der Universität Ulm (OPARU) (Ulm University)”

Zebrafish can fully regenerate heart tissue after injury, aided by Wnt signaling.

Immunoreactivity of the SARS-CoV-2 Entry Proteins ACE-2 and TMPRSS-2 in Murine Models of Hormonal Manipulation, Aging, and Cardiac Injury

research Immunoreactivity of the SARS-CoV-2 entry proteins ACE-2 and TMPRSS-2 in murine models of hormonal manipulation, ageing, and cardiac injury

5 citations , December 2021 in “Scientific Reports”

Age affects how certain proteins involved in COVID-19 infection are expressed in mice, but sex hormones and heart injury do not.

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