research The pathogenesis of alopecia areata
Alopecia areata is an autoimmune disease affecting hair follicles and may harm heart health.
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research The G-Protein Couple Receptor Kinase 2 (GRK2) Orchestrates Hair Follicle Homeostasis
GRK2 is essential for healthy hair follicle function, and its absence can lead to hair loss and cysts.
research Role of stem/progenitor cells in reparative disorders
Adult stem cells are important for tissue repair and have therapeutic potential, but more research is needed to fully use them.
research Novel in vitro culture condition improves the stemness of human dermal stem/progenitor cells
New culture method keeps human skin stem cells more stem-like.
research Accelerated Endothelial to Mesenchymal Transition Increased Fibrosis via Deleting Notch Signaling in Wound Vasculature
Disrupting Notch signaling in blood vessels increases scarring during wound healing in mice.
research Finasteride: The First 5α-Reductase Inhibitor
Finasteride treats enlarged prostate and baldness, but may cause limited urinary improvement and sex-related side effects.
research Enhanced viability and neural differential potential in poor post-thaw hADSCs by agarose multi-well dishes and spheroid culture
Spheroid culture in agarose dishes improves survival and nerve cell growth in thawed human fat-derived stem cells.
research Male, Female, Other: Transgender and the Impact in Primary Care
Healthcare providers need better education and resources to give competent and sensitive care to transgender patients.
research LUPUS ERYTHEMATOSUS AND THE SKIN
Lupus affects the skin in various ways, and proper skin examination is crucial for diagnosis and treatment.
research M5 isolation method preserves higher trichogenic identity and proliferative capacity of human dermal papilla cells
The M5 method is best for isolating cells that help hair growth.
research Comparative gene expression analysis of nestin-expressing hair follicle-derived cells
Nestin-expressing hair follicle cells may be useful for nerve repair and regeneration.
research ATP-dependent chromatin remodeling during mammalian development
ATP-dependent chromatin-remodeling complexes are crucial for gene regulation, cell differentiation, and organ development in mammals.
research Administration of Caesalpinia bonduc Seed Extracts Ameliorates Testosterone-Induced Benign Prostatic Hyperplasia (BPH) in Male Wistar Rats
Caesalpinia bonduc seed extracts may help treat enlarged prostate in rats.
research Gonads
The document concludes that accurate diagnosis of male and female gonadal disorders is crucial for effective treatment and better patient outcomes.
research Increased Polyamine Concentrations in the Hair of Cancer Patients
Hair can be used to measure cancer-related chemicals noninvasively.
research Rodent models in placental research. Implications for fetal origins of adult disease
Using rodents for research shows that health problems in the womb can cause diseases later in life.
research Hair cortisol in polycystic ovary syndrome
Women with PCOS have higher hair cortisol levels, which are linked to worse metabolic and inflammatory conditions.
research The senescence-like activity of BMS-470539 is associated with anti-fibrotic actions in models of dermal fibrosis
BMS-470539 reduces skin fibrosis and inflammation.
research Risk of Periodontal Diseases in Women With Polycystic Ovary Syndrome: An Overview
Women with PCOS are at higher risk for gum disease, and managing shared risk factors can help both conditions.
research 976 Knockout of mTOR/Akt inhibitor REDD1 results in hair cycle-independent dermal adipose expansion by promoting adipocyte differentiation
Removing REDD1 in mice increases skin fat by making fat cells larger and more numerous.
research Peer Review #1 of "Induced pluripotent stem cells from human hair follicle keratinocytes as a potential source for in vitro hair follicle cloning (v0.1)"
Human hair follicle cells can be turned into stem cells that may help clone hair for treating hair loss or burns.
research Comparison of mitochondrial transplantation by using a stamp-type multineedle injector and platelet-rich plasma therapy for hair aging in naturally aging mice
Mitochondrial therapy and platelet-rich plasma therapy both stimulated hair regrowth in aging mice, with mitochondrial therapy showing similar effectiveness to plasma therapy.
research Hair follicle immune privilege in autoimmune and immune-mediated alopecias: paths toward reestablishing immune tolerance
Different types of alopecia cause hair loss due to immune system issues, with some allowing regrowth and others causing permanent loss.
research Androgen Signaling Regulates SARS-CoV-2 Receptor Levels and Is Associated with Severe COVID-19 Symptoms in Men
Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.
research Mammalian-specific ectodermal enhancers control the expression of Hoxc genes in developing nails and hair follicles
HoxC genes are crucial for normal hair and nail development.
research Cardiac and Renal SARS-CoV-2 Viral Entry Protein Regulation by Androgens and Diet: Implications for Polycystic Ovary Syndrome and COVID-19
Androgens and a high-fat diet may increase the risk of severe COVID-19 in women with PCOS by upregulating certain proteins in the heart and kidneys.
research Langerin+ Dendritic Cells in Cutaneous Fibrosis: The TGF-β1 Signaling Axis
Targeting specific cell interactions may help treat skin fibrosis.
research Genomic Markers and Personalized Medicine in Androgenetic Alopecia: A Comprehensive Review
Personalized treatments for hair loss are becoming more effective by using genetic information.
research Childhood Systemic Lupus Erythematosus: Clinical and Immunologic Patterns in Mexican Children
Gender-specific analysis could improve treatment for childhood systemic lupus erythematosus.
research Genotype Triad for HOTAIR rs10783618, LINC-ROR rs1942347, and MALAT1 rs3200401 as Molecular Markers in Systemic Lupus Erythematous
Certain genetic markers can indicate higher or lower risk for systemic lupus erythematosus.