506 citations
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January 2012 in “Molecular and Cellular Endocrinology” Melatonin affects many body functions beyond sleep by interacting with specific receptors in various tissues.
252 citations
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February 2018 in “npj Regenerative Medicine” Understanding different species' regeneration can improve mammalian healing.
194 citations
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May 2000 in “Journal of Investigative Dermatology” The hedgehog signaling pathway is crucial for hair growth but not for the initial creation of hair follicles.
125 citations
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May 2019 in “Phytomedicine” Cepharanthine is a well-tolerated drug with multiple medical uses, including anti-inflammatory and anti-cancer properties.
103 citations
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March 2015 in “Nature Communications” A genetic region near the PAX1 gene is linked to a higher risk of scoliosis in females.
61 citations
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October 2013 in “PLoS ONE” Boosting Wnt signaling improves skin wound healing.
50 citations
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April 2014 in “Nature Communications” The research identified new skin traits in mice, some linked to human skin conditions.
47 citations
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March 2016 in “Journal of dermatology” Understanding the genetics of rare inherited ichthyosis syndromes is key for better treatments and genetic counseling.
47 citations
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November 2012 in “Wound repair and regeneration” Nude mice with grafted human skin developed scars similar to human hypertrophic scars.
42 citations
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January 2011 in “Journal of Biomedical Optics” Infrared and Raman imaging can non-destructively analyze hair structure and help diagnose hair conditions.
40 citations
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May 2016 in “Proceedings of the National Academy of Sciences of the United States of America” Changes in keratin make hair follicles stiffer.
39 citations
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April 2024 in “Frontiers in Endocrinology” New treatments aim to improve thin endometrium to help more couples with infertility.
38 citations
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November 2012 in “Expert Opinion on Drug Safety” Common acne treatments can cause various side effects, like skin irritation and more serious issues, but combination therapies are often more effective and better tolerated.
38 citations
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June 2005 in “Matrix Biology” Minoxidil affects collagen-related genes, potentially helping treat fibrosis.
36 citations
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January 2012 in “International Journal of Trichology” Losing eyelashes or eyebrows can be a sign of many different health problems and needs a careful approach to treat effectively.
29 citations
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July 2008 in “Journal of Cutaneous Pathology” Hair root sheaths are more common in non-scarring hair loss and help diagnose the type of hair loss.
26 citations
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January 1994 in “Clinics in Dermatology” Artificial skin is improving wound healing and shows potential for treating different types of wounds.
25 citations
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May 2020 in “Daehan saengsik uihak hoeji/Clinical and experimental reproductive medicine” Injecting platelet-derived growth factors into ovaries may improve IVF outcomes by enhancing egg quality and embryo health.
25 citations
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May 2016 in “Progress in Biophysics & Molecular Biology” R-spondins and their receptors help increase bone growth and may be used to treat bone loss diseases.
24 citations
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July 2022 in “Journal of Applied Pharmaceutical Science” Optimizing production conditions can improve hyaluronic acid's effectiveness and cost in cosmetics and therapy.
24 citations
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October 2017 in “Biomolecules” Some growth factors, while important for normal body functions, can cause diseases when not regulated properly.
22 citations
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August 2006 in “Critical Reviews in Plant Sciences” The tropical legume Sesbania rostrata can form nodules in waterlogged conditions using a different method that involves plant hormones and specific genes.
21 citations
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June 2019 in “Dermatologic Surgery” Platelet-rich plasma (PRP) treatment has been found effective in promoting hair growth for alopecia patients, with minimal side effects like temporary pain and redness.
20 citations
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October 2018 in “American Journal of Clinical Dermatology” Some drugs can cause skin and hair color changes, often reversible when the drug is stopped.
19 citations
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June 2020 in “Animals” Poor maternal nutrition can lead to fewer wool follicles in Chinese Merino sheep.
16 citations
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November 1992 in “Journal of International Medical Research” ViviScal®, a food supplement, was found to be highly effective in treating hereditary hair loss in young males, while fish extract showed no impact.
15 citations
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January 2020 in “ACS Applied Materials & Interfaces” Nanofiber structure helps regenerate hair follicles.
15 citations
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February 2015 in “Han-gug chugsan sigpum hag-hoeji/Korean journal for food science of animal resources” Egg shell membrane hydrolysates can reduce wrinkles and improve skin health.
15 citations
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November 2002 in “Cardiology in Review” Cardiovascular drugs can cause various skin problems, so recognizing these reactions is important.
14 citations
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August 2007 in “Bioorganic & Medicinal Chemistry Letters” The compound (1R,2S)-4-(2-Cyano-cyclohexyl-oxy)-2-trifluoromethyl-benzonitrile can stimulate hair growth and reduce oil production when applied topically.