research Types I and II Keratin Intermediate Filaments
Keratins are crucial for cell structure, growth, and disease risk.
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research Sulfatase inhibitors: a patent review
The document concludes that research on sulfatase inhibitors should continue due to their potential in treating various diseases, despite some clinical trial failures.
research Human epithelial stem cell survival within their niche requires “tonic” cannabinoid receptor 1‐signalling—Lessons from the hair follicle
Cannabinoid receptor-1 signaling is essential for the survival and growth of human hair follicle stem cells.
research Synergistic effect of sorafenib with Platycladus orientalis (L) leaf extract on cervical cancer
Sorafenib and Platycladus orientalis leaf extract together effectively suppress cervical cancer cell growth.
research Phytochemical and nanoparticle-based therapeutic potential of Sphaeranthus indicus against hepatocellular carcinoma via cryptomeridiol targeting
Sphaeranthus indicus and silver nanoparticles can help treat liver cancer by killing cancer cells.
research Angiopoietin-1 induces survival and proliferation of hair follicle dermal papilla cells through integrin α5β1 signaling
Angiopoietin-1 helps hair cells survive and grow, making it a potential treatment for hair loss.
research Highlights from the 68th Annual Meeting of the Society of Investigative Dermatology
The meeting discussed vitamin D3's role in fighting tuberculosis, potential treatments for skin conditions like psoriasis, and hair follicle regeneration as a possible solution for hair loss.
research Indian Gooseberry (Emblica officinalisGaertn.)
Indian Gooseberry has potential for cancer prevention and treatment and promotes hair growth.
research Modulating testosterone pathway: a new strategy to tackle male skin aging?
Honokiol might help reduce male skin aging by maintaining testosterone levels.
research Anti-proliferative effect of terpenes on human prostate cáncer cells: natural sources and their potential role as chemopreventive agents.
Certain natural compounds called terpenes may help prevent prostate cancer.
research Septin4 promotes cell death in human colon cancer cells by interacting with BAX
Septin4 helps kill colon cancer cells by working with the protein BAX.
research Ginseng phytochemicals as therapeutics in oncology: Recent perspectives
Ginseng may help treat cancer and reduce treatment side effects, but more research is needed.
research Alleviation of Multidrug Resistance by Flavonoid and Non-Flavonoid Compounds in Breast, Lung, Colorectal and Prostate Cancer
Some natural compounds may help overcome drug resistance in certain cancers, but more research is needed.
research Adverse health effects of androgen use
Using anabolic androgenic steroids can cause serious, lasting health problems in many parts of the body.
research THE GLOBAL CHALLENGE OF CHEMOTHERAPY TOXICITY: RETHINKING SUPPORTIVE CARE IN MODERN ONCOLOGY
Better supportive care is needed to manage chemotherapy side effects.
research Defining the impact of β-catenin/Tcf transactivation on epithelial stem cells
β-catenin is essential for stem cell activation and proliferation in hair follicles.
research Review of Pharmacological Effects ofMyrtus communisL. and its Active Constituents
Myrtle has various health benefits and potential for medicine development.
research Probiotic Bacteria Induce a ‘Glow of Health’
Probiotic bacteria improved skin and hair health in aged mice.
research c-MYC-Induced Sebaceous Gland Differentiation Is Controlled by an Androgen Receptor/p53 Axis
The balance between androgen receptor and p53 is crucial for sebaceous gland differentiation.
research Stem cell plasticity enables hair regeneration following Lgr5+ cell loss
Hair can regrow after certain stem cells are lost because other stem cells can take over their role.
research Activation of Wnt Signaling in Hematopoietic Regeneration
Wnt10b helps blood stem cells grow after injury.
research Steroid plant hormones: Effects outside plant kingdom
Plant steroid hormones show growth, health, and medicinal benefits in various organisms, including potential for treating diseases.
research Cell Cycle Regulation and Regeneration
Mice that can regenerate tissue have cells that pause in the cell cycle, which is important for healing, similar to axolotls.
research Development of Autoimmune Hair Loss Disease Alopecia Areata Is Associated with Cardiac Dysfunction in C3H/HeJ Mice
Mice with autoimmune hair loss showed signs of heart problems.
research New potential chemotherapy for ovarian cancer — Combined therapy with WP 631 and epothilone B
The new chemotherapy combination of WP 631 and Epothilone B shows enhanced effectiveness against ovarian cancer but requires more research on its safety.
research Androgen receptor activation integrates complex transcriptional effects in osteoblasts, involving the growth factors TGF-β and IGF-I, and transcription factor C/EBPδ
DHT affects bone growth by altering gene activity in osteoblasts, potentially complicating steroid use.
research Next-Gen Therapeutics for Skin Cancer: Nutraceuticals
Certain spices may help prevent and treat skin cancer, but more human trials are needed.
research Essential Role of STAT3 Signaling in Hair Follicle Homeostasis
STAT3 signaling is important for healthy skin and hair follicles, and its disruption can lead to skin conditions like atopic dermatitis.
research Purple corn extract improves benign prostatic hyperplasia by inhibiting 5 alpha-reductase type 2 and inflammation in testosterone propionate-induced rats
Purple corn extract may help reduce prostate enlargement and inflammation.
research Hepatology highlights
Tenofovir is more effective than adefovir for resistant hepatitis B, Fibroscan is good for assessing liver damage, regulatory T cells may help hepatitis C persist, and other insights into liver health and disease were found.