125 citations
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January 1999 in “Drugs” Finasteride effectively treats baldness but may cause sexual side effects.
123 citations
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February 2002 in “Journal of The American Academy of Dermatology” Minoxidil can cause skin allergy; use alternative solvents or treatments if allergic.
121 citations
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November 2020 in “Endocrine” Male hormones like testosterone may make COVID-19 worse, and testing for sensitivity to these hormones could help predict how severe a patient's symptoms might be. Treatments that reduce these hormones are being explored.
91 citations
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July 2010 in “Tissue Engineering Part A” Low-oxygen conditions and ECM degradation products increase the healing abilities of perivascular stem cells.
87 citations
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March 2000 in “American Journal of Clinical Dermatology” Alpha-hydroxy acids, like glycolic acid, safely improve skin issues and work on all skin types.
78 citations
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January 2000 in “Gynecological Endocrinology” Norgestimate is the most effective birth control progestin for reducing an enzyme linked to acne and excessive hair growth in women.
55 citations
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September 2017 in “Journal of Cosmetic Dermatology” Platelet-rich plasma, taken from a person's own blood, can help rejuvenate skin, stimulate hair growth, and treat hair loss, but more research is needed to confirm its safety and effectiveness.
46 citations
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August 2019 in “Journal of Ethnopharmacology” Eclipta prostrata has many traditional uses and health benefits, but more research is needed to understand how it works and ensure it's safe.
46 citations
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May 2012 in “Molecular and Cellular Endocrinology” Human skin produces sex hormones like estrogen and testosterone, influenced by ARO and StAR, which may affect skin elasticity and hair growth.
38 citations
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June 2004 in “Human Reproduction” The document suggests that clinical trials for PCOS should focus on meaningful primary outcomes like live birth rates, rather than less reliable surrogate markers.
35 citations
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May 2015 in “Thrombosis Research” Prostaglandin E2 affects human platelet activity in complex ways that could lead to personalized heart disease treatments.
33 citations
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October 2016 in “European Journal of Pharmaceutical Sciences” Effervescent formulations may improve minoxidil delivery, increasing effectiveness and reducing applications needed.
25 citations
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October 2019 in “Journal of Endocrinological Investigation” Both types of oral contraceptives improved symptoms and hormone levels in women with PCOS.
22 citations
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November 2016 in “Indian Journal of Pharmaceutical Education and Research” Hibiscus rosa-sinensis leaf extract is safe, has strong antioxidants, and effectively heals wounds.
21 citations
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November 2010 in “Talanta” Researchers developed a reliable method to measure testosterone and epitestosterone in urine for medical and anti-doping use.
21 citations
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December 2007 in “Primary Care” Early diagnosis and treatment of PCOS is crucial to reduce emotional distress and health risks.
21 citations
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August 2003 in “Seminars in oncology nursing” Nurses are crucial in managing chemotherapy side effects for ovarian cancer patients to improve their quality of life.
21 citations
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October 1978 in “The Journal of Clinical Pharmacology”
19 citations
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December 2016 in “PLOS ONE” Early-stage skin cells help regenerate hair follicles, with proteins SDF1, MMP3, biglycan, and LTBP1 playing key roles.
18 citations
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May 2014 in “Menopause” A 5 mg dose of transdermal testosterone cream effectively restores testosterone levels in postmenopausal women.
18 citations
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October 2012 in “Dermatologic Clinics” Early diagnosis and aggressive treatment are key for managing rare scalp disorders that cause permanent hair loss.
18 citations
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June 1999 in “Statistical Methods in Medical Research” The document concludes that PK/PD modeling is important for determining the safe and effective dosages of drugs.
15 citations
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January 1998 in “Journal of Clinical Periodontology” Finasteride helps treat hair loss by blocking enzyme activity.
14 citations
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April 2017 in “Scientific Reports” Using a perfusion system and 3D spheroid culture improves the growth of corneal cell layers for tissue engineering.
13 citations
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June 2020 in “Stem Cells International” A substance from a specific gel helped to grow hair effectively in mice, suggesting it could potentially be used to treat hair loss in humans.
11 citations
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January 2006 in “Drug development and industrial pharmacy” Adding TPGS to minoxidil solutions can improve skin penetration and retention, especially in water and PEG 400-based solutions.
10 citations
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January 2016 in “Elsevier eBooks” Nanoparticles can speed up wound healing and deliver drugs effectively but may have potential toxicity risks.
9 citations
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June 2021 in “International Journal of Pharmaceutics” Using polymeric micelles to deliver spironolactone topically could improve wound healing in skin affected by glucocorticoids.
9 citations
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November 2017 in “International Journal of Nanomedicine” Tiny particles called anionic squarticles can effectively remove a common antidepressant from the body after an overdose.
7 citations
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February 2021 in “Legal Medicine” Hair analysis showed very high metformin levels in two fatal overdose cases, suggesting it's useful in forensics but sweat may affect results.