April 2026 in “Inflammation and Regeneration” AKR1C enzymes in scalp glands decrease with age, possibly affecting hair loss.
38 citations
,
May 2010 in “American Journal Of Pathology” 17β-Estradiol slows wound healing in male mice through estrogen receptor-α.
18 citations
,
October 2017 in “PLOS ONE” The study concluded that similar pathways regulate hair growth in dogs and mice, and these pathways are disrupted in dogs with Alopecia X, affecting stem cells and hormone metabolism.
12 citations
,
March 2017 in “Arteriosclerosis, thrombosis, and vascular biology” Testosterone helps prevent skin damage in males by acting through both estrogen and androgen pathways.
January 2025 in “Brazilian Journal of Veterinary Medicine/Revista Brasileira de Medicina Veterinária” Deslorelin implant successfully regrew hair in a female Pomeranian with alopecia X.
December 2023 in “International Journal of Research in Dermatology” Hormonal imbalances are important in the development of male pattern baldness.
September 2023 in “Middle East Fertility Society Journal” Nicotine may help treat both Parkinson's disease and infertility.
July 2023 in “The Journal of Clinical Endocrinology and Metabolism” Gender-affirming hormone therapy improves physical performance in trans men to the level of cisgender men, while in trans women, it increases fat mass and decreases muscle mass, with no advantage in physical performance after 2 years.
31 citations
,
January 1989 in “The Prostate/The prostate” Estradiol and castration reduced prostate cancer development in rats when applied at early stages, but were ineffective after cancer was established.
23 citations
,
January 1998 in “Urological research” Castration and finasteride lower urinary oxalate in male rats, potentially treating urolithiasis.
1 citations
,
August 2013 in “PubMed” Testosterone changes reduce thyroxin levels in rats.
December 2016 in “The Journal of urology/The journal of urology” Castration significantly reduces prostate size and BPH symptoms.
8 citations
,
February 2021 in “Journal of the American Heart Association” Medical castration in prostate cancer patients can increase the risk of serious heart rhythm problems, so it's important to monitor heart activity during treatment.
April 2020 in “The FASEB Journal” Surgical and chemical castration have varied effects on heart and brain inflammation and artery function in sick rats.
108 citations
,
September 2002 in “The Journal of clinical investigation/The journal of clinical investigation” Lowering testosterone speeds up wound healing in male mice.
38 citations
,
August 2003 in “International Journal of Urology” Finasteride and levofloxacin effectively reduce chronic bacterial prostatitis severity.
29 citations
,
February 1987 in “General and comparative endocrinology” Thyroid and gonadal hormones control seasonal hair growth and molting in male European badgers.
18 citations
,
September 1972 in “British Journal of Pharmacology” PCPA induces hypersexual behavior in male rats regardless of age or castration status.
9 citations
,
September 2002 in “The Journal of clinical investigation/The journal of clinical investigation” Blocking testosterone speeds up wound healing in males.
5 citations
,
January 2010 in “The Journal of Internal Korean Medicine” Lygodium japonicum may help treat benign prostatic hyperplasia.
1 citations
,
April 2021 in “Journal of Cardiovascular Pharmacology” Testosterone plays a big role in heart and nervous system damage caused by inflammation in male rats, suggesting that blocking testosterone production could help manage this condition.
April 2020 in “The FASEB Journal” Testosterone increases heart and blood pressure issues in rats with endotoxemia, and stopping testosterone production can reduce these problems.
July 2019 in “Acta Scientiae Veterinariae” Removing a testicular tumor in a dog reduced its aggressive behavior and skin problems.
May 2019 in “bioRxiv (Cold Spring Harbor Laboratory)” Testosterone significantly affects urination differences between male and female mice.
January 2015 in “VetPharma” Alopecia X causes hair loss in young plush-coated dogs and can be treated with various therapies, but hair may regrow and then fall out again.
Check hormone levels and blood counts before surgery in dogs with abnormal blood cell counts.
September 2010 in “Companion Animal” The guide explains how to diagnose and treat hair loss in dogs, covering causes and treatments, with some conditions lacking treatment options.
January 2010 in “Journal of Oriental Medicine” Phellodendri Cortex Extract may help treat enlarged prostate.
October 2006 in “Urology” The document aimed to understand how certain treatments affect blood vessel growth in rat prostates.
January 2003 in “Zhonghua shiyan waike zazhi” Androgen, especially DHT, is crucial for erectile function in rats by affecting specific brain neurons.