46 citations
,
June 2018 in “American Journal of Clinical Dermatology” Hair loss is common in lupus patients and can be permanent or reversible, depending on the type, with various treatments available.
41 citations
,
November 2013 in “Experimental Dermatology” Leptin, a hormone, is important for starting hair growth.
40 citations
,
November 1998 in “The journal of investigative dermatology/Journal of investigative dermatology” S100A3 protein is crucial for hair shaft formation in mice.
33 citations
,
April 2005 in “British Journal of Dermatology” Aging alone barely affects the number of hair follicles, meaning hair loss is minimal without other conditions like androgenetic alopecia.
32 citations
,
April 2016 in “Journal of Investigative Dermatology” STAT5 activation is crucial for starting the hair growth phase.
31 citations
,
April 2010 in “British journal of dermatology/British journal of dermatology, Supplement” Frontal fibrosing alopecia can cause sudden hair loss on limbs, similar to scalp hair loss.
31 citations
,
April 2007 in “Experimental Dermatology” Stress in mice delays hair growth and treatments blocking substance P can partly reverse this effect.
26 citations
,
July 2016 in “PLOS ONE” Activating β-catenin in certain skin cells speeds up hair growth in mice.
26 citations
,
March 1986 in “Clinical and Experimental Dermatology” Scalp hair grows at 0.37 mm/day, forearm hair at 0.18 mm/day, and thigh hair at 0.30 mm/day, with no significant differences found in people with certain hair conditions.
24 citations
,
January 2011 in “International Journal of Trichology” Light microscopy is useful for diagnosing different hair disorders.
23 citations
,
May 1998 in “Journal of Dermatological Science” Insulin or IGF-I is needed for hair growth in newborn mice, while minoxidil helps adult mouse hair grow, suggesting a way to study human hair loss.
21 citations
,
May 1996 in “Current problems in dermatology” Detailed patient history and physical exams are crucial for diagnosing hair loss.
20 citations
,
January 2015 in “Current problems in dermatology” Graying hair happens due to aging and might be delayed by new treatments.
17 citations
,
September 2012 in “Dermatologic Clinics” The conclusion is that accurate diagnosis of different types of hair loss requires careful examination of tissue samples and understanding of clinical symptoms.
16 citations
,
December 2006 in “Expert Review of Dermatology” Hair follicles are essential for skin health, aiding in hair growth, wound healing, and immune function.
14 citations
,
December 2020 in “Journal of Investigative Dermatology” Aging causes changes in the scalp that can affect hair growth and lead to older-looking hair in women.
13 citations
,
March 2020 in “Genes” Disrupting the FGF5 gene in rabbits leads to longer hair by extending the hair growth phase.
12 citations
,
October 2020 in “Scientific Reports” Necrostatin-1s can promote hair growth and may help treat hair loss.
9 citations
,
July 2014 in “Experimental Dermatology” PTHRP agonists can stimulate hair growth, especially in damaged follicles, while antagonists may initially increase growth but ultimately inhibit it.
8 citations
,
June 2019 in “Journal of Ginseng Research” Gintonin-enriched fraction promotes hair growth and could be a potential alopecia treatment.
8 citations
,
February 2017 in “Archives of Dermatological Research” Intense pulsed light treatment effectively reduces underarm hair by making hair follicles smaller and extending their resting phase.
7 citations
,
November 2013 in “Pediatric and Developmental Pathology” Over half of the children had abnormal hair under a microscope, with many having genetic hair conditions.
6 citations
,
August 2019 in “PLOS ONE” Gambogic Amide helps maintain hair color and promotes hair growth.
6 citations
,
March 2011 in “Experimental Dermatology” Too much or too little selenium in the diet can cause hair loss and graying in mice.
6 citations
,
November 1988 in “Journal of the American Academy of Dermatology” The document concludes that hair analysis is not good for assessing nutrition but can detect long-term heavy metal exposure.
5 citations
,
January 2013 in “Cells Tissues Organs” Activin B helps start and grow hair follicles in mice.
5 citations
,
September 2012 in “Journal of Investigative Dermatology” Scientists can mimic hair disorders by altering genes in lab-grown human hair follicles, but these follicles lack some features of natural ones.
4 citations
,
July 2020 in “BMC Complementary Medicine and Therapies” Human placenta helps hair grow back after chemotherapy by blocking cell death and increasing hair follicle growth.
3 citations
,
January 2011 in “Wspolczesna Onkologia-Contemporary Oncology” Scalp hypothermia can prevent chemotherapy-induced hair loss but is not suitable for all patients, and more research is needed to improve prevention methods.
2 citations
,
January 2023 in “International journal of biological sciences” Gray hair can potentially be reversed, leading to new treatments.