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research Cepharanthine Suppresses Herpes Simplex Virus Type 1 Replication Through the Downregulation of the PI3K/Akt and p38 MAPK Signaling Pathways

30 citations , December 2021 in “Frontiers in Microbiology”

Cepharanthine effectively reduces Herpes Simplex Virus Type 1 by blocking certain cell pathways and promoting cell death.

research Hair-specific expression of chloramphenicol acetyltransferase in transgenic mice under the control of an ultra-high-sulfur keratin promoter.

33 citations , September 1990 in “Proceedings of the National Academy of Sciences”

The study showed that a specific DNA sequence can control gene expression in hair growth areas of mice.

research Development of Effervescent Cleansing Tablets Containing Asiatic-Acid-Loaded Solid Lipid Microparticles

3 citations , October 2023 in “Cosmetics”

Effervescent cleansing tablets with Asiatic acid were successfully developed, showing good stability and cleansing effectiveness.

research UNCONVENTIONAL PROTEIN SECRETION OF KERATIN 75 BY AMELOBLASTS IN VIVO

April 2018 in “D-Scholarship@Pitt (University of Pittsburgh)”

Keratin-75 is secreted by ameloblasts in a unique way without a signal peptide.

research Recombinant Bacillus subtilis-derived alkaline protease: a novel agent for skin depigmentation and hair follicle neogenesis

January 2025 in “Archives of Dermatological Research”

research Cytoplasmic Ca2+ concentrations in intact Merkel cells of an isolated, functioning rat sinus hair preparation

49 citations , March 1996 in “Experimental Brain Research”

A Case of MBTPS1-Related Disorder Due to Compound Heterozygous Variants in MBTPS1 Gene: Genotype-Phenotype Expansion and the Emergence of a Novel Syndrome

research A case of MBTPS1‐related disorder due to compound heterozygous variants in MBTPS1 gene: Genotype–phenotype expansion and the emergence of a novel syndrome

December 2023 in “American journal of medical genetics. Part A”

A new syndrome was linked to two new genetic changes in the MBTPS1 gene in a 14-year-old girl.

research NEW NON SYNTHETIC MOLECULES ARE ABLE TO INHIBIT APOPTOSIS IN DERMAL PAPILLAR CELLS OF HAIR BULB

January 2011 in “Archivio Istituzionale della Ricerca (Universita Degli Studi Di Milano)”

New molecules can prevent cell death in hair follicles.

Therapeutic Targeting of Ocular Diseases with Emphasis on PI3K/Akt and OPRL Pathways by Hedera Helix L. Saponins: A New Approach for the Treatment of Pseudomonas Aeruginosa-Induced Bacterial Keratitis

research Therapeutic targeting of ocular diseases with emphasis on PI3K/Akt, and OPRL pathways by Hedera helix L. saponins: a new approach for the treatment of Pseudomonas aeruginosa-induced bacterial keratitis

1 citations , May 2025 in “Natural Products and Bioprospecting”

PEVIII is a promising treatment for Pseudomonas aeruginosa keratitis.

research Degradation of Human Hair by Papain

75 citations , November 1965 in “Textile research journal”

Papain and bisulfite break down human hair by dissolving parts of it.

research Trans glutaminase-mediated cross-linking in mammalian epidermis

44 citations , January 1984 in “Molecular and Cellular Biochemistry”

research Collagen triple helix repeat containing-1 promotes functional recovery of sweat glands by inducing adjacent microvascular network reconstruction in vivo

3 citations , January 2022 in “Burns & Trauma”

CTHRC1 helps sweat glands recover by rebuilding nearby blood vessels.

research How the leopard gets its spots: a transmembrane peptidase specifies feline pigmentation patterns

March 2013 in “Pigment Cell & Melanoma Research”

A gene called Taqpep affects cat coat patterns like stripes and blotches.

research Relationships between hair-follicle afferent terminations and glutamic acid decar☐ylase-containing boutons in the cat's spinal cord

46 citations , April 1987 in “Brain Research”

research Experimental and Finite Element Analysis of a Residual Hair Keratin‐based Hydrogel with Calcium for Atorvastatin Sequestration, Release, and In Vitro Activity

February 2026 in “Macromolecular Bioscience”

Keratin-based hydrogels with calcium are effective for delivering anti-fibrotic drugs.

research Comparison of two ASC-derived therapeutics in an in vitro OA model: secretome versus extracellular vesicles

60 citations , December 2020 in “Stem Cell Research & Therapy”

ASC-CM is more effective than EV for treating osteoarthritis.

research An Updated Nomenclature for Keratin-Associated Proteins (KAPs)

92 citations , January 2012 in “International Journal of Biological Sciences”

The document introduced a new naming system for keratin-associated proteins to improve clarity and communication across species.

research Proteolytic Enzymes Papain and Chymotrypsin Combined with Laser Techniques for the Management of Facial Hirsutism

1 citations , December 2022 in “Planta Medica”

Combining enzymes papain and chymotrypsin with laser treatment reduces facial hair more effectively than laser alone.

research Pharmacological evidence for the involvement of adenosine triphosphate sensitive potassium channels in chloroquine-induced itch in mice

9 citations , June 2017 in “Pharmacological Reports”

ATP-sensitive potassium channels play a role in chloroquine-induced itch in mice.

research Lipid-based liquid crystals as drug delivery vehicles for antimicrobial peptides

5 citations , January 2017 in “Chalmers Publication Library (Chalmers University of Technology)”

Cubosomes enhance antimicrobial peptide stability and effectiveness.

A Keratinocyte-Specific Epoxygenase, CYP2B12, Metabolizes Arachidonic Acid with Unusual Selectivity, Producing a Single Major Epoxyeicosatrienoic Acid

research A Keratinocyte-specific Epoxygenase, CYP2B12, Metabolizes Arachidonic Acid with Unusual Selectivity, Producing a Single Major Epoxyeicosatrienoic Acid

58 citations , April 1998 in “Journal of biological chemistry/The Journal of biological chemistry”

CYP2B12 enzyme in skin cells converts arachidonic acid into specific bioactive lipids.

research Biochemical Evidence That Small Proline-rich Proteins and Trichohyalin Function in Epithelia by Modulation of the Biomechanical Properties of Their Cornified Cell Envelopes

99 citations , May 1998 in “Journal of biological chemistry/The Journal of biological chemistry”

Small proline-rich proteins and trichohyalin help make epithelial tissues tougher and more flexible.

research Molecular docking simulation studies on potent butyrylcholinesterase inhibitors obtained from microbial transformation of dihydrotestosterone

8 citations , October 2013 in “Chemistry Central Journal”

Metabolite 7 is a strong inhibitor for Alzheimer's disease management.

research DiZyme: The Ultimate Resource for Nanozyme Multiple Catalytic Activity Prediction

1 citations , November 2023 in “Research Square (Research Square)”

DiZyme accurately predicts nanozyme activities to aid in discovering new applications.

research The effect of proteolytic enzymes on hair follicles of transgenic mice expressing the lac Z‐protein in cells of the bulge region

5 citations , July 1999 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology”

Proteolytic enzymes damage hair follicles by detaching stem cells.

research Protein Kinase C as a Therapeutic Target

87 citations , September 2006 in “Clinical Cancer Research”

Protein Kinase C shows promise for cancer treatment, but more research is needed to develop effective inhibitors.

research The effect of polyphloretin phosphate, polyoestradiol phosphate, a diphosphonate and a polyphosphate on calcification induced by dihydrotachysterol in skin, aorta and kidney of rats

31 citations , February 1972 in “Experientia”

The diphosphonate was the most effective at preventing calcification in rats.

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