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Mutations at Val-889 and Arg-752 disrupt key interactions in the androgen receptor, affecting its function.

The protein folliculin, involved in a rare disease, works with another protein to control how cells stick together and their organization, and changes in this interaction can lead to disease symptoms.

CaBP1 and 2 are important for maintaining the activity of calcium channels necessary for hearing in inner ear cells.

CB-03-01 is a promising skin cream for treating hormone-related skin problems without causing harmful body-wide effects.

Some dibenzo compounds might help treat cancer with fewer side effects.

GD-23 reduces anxiety by relying on neurosteroid production.

Researchers found new potential treatments for conditions related to the androgen receptor, like male hormonal contraception, by testing thousands of compounds.

Neurosteroids regulate synaptic inhibition in the spinal cord and may help manage spinal pain.

Activating liver X receptors can reduce fibrosis by stopping certain immune cells from releasing harmful proteins.

Some cannabinoid derivatives may be more effective than current drugs at targeting proteins relevant to prostate cancer treatment.

LGR5 mainly stays inside cells, moving to the trans-Golgi network, and this process is important for its role in cell signaling.

Lipid-antigen stimulation may play a role in folliculotropic mycosis fungoides.

The research found that androgens help control blood flow in the rat prostate through a specific binding site.

Newly designed proteins can effectively degrade specific proteins in cells, offering a potential new therapy method.

Cedrol promotes hair growth better than baricitinib by regulating immune cells.

The compound 4c showed strong potential as an anticancer agent.

The study concludes that certain domains in Clostridium histolyticum enzymes are structurally unique, bind calcium to become more stable, and play distinct roles in breaking down collagen, with potential applications in medicine and drug delivery.

The conclusion is that a new test was created to find substances that affect specific ion channels, and it works well for drug discovery.

Hairless protein can both repress and activate vitamin D receptor functions, affecting gene regulation.

Targeting Hedgehog signaling may help treat ligamentum flavum fibrosis.

A new compound effectively inhibits human 5α-reductase 1.

A new compound, 3a, effectively fights prostate cancer better than finasteride.

Some newly made compounds are promising for treating enlarged prostate, hair loss, viruses, and prostate cancer, and might be better than current drugs.

Five preservatives may disrupt hormone function and need more health and environmental risk assessment.

Signaling mechanisms, including TRPV channels and cannabinoid receptors, are important in skin and hair biology.

Galectin-1 helps in RNA processing in cell nuclei.

Steroid-binding globulins have important roles beyond just transporting steroids.

LY320236 is a strong blocker of two enzymes that change testosterone into dihydrotestosterone and might help treat conditions related to male hormones.

CaBP1 and 2 are necessary for maintaining calcium currents and hearing in inner ear cells.

AKR1D1 controls glucocorticoid levels and receptor activity in liver cells.