2 citations
,
March 2021 in “Molecular Immunology” Dermal macrophages might help regrow hair.
60 citations
,
September 2015 in “Expert Review of Clinical Immunology” Lymphocytes, especially CD8+ T cells, play a key role in causing alopecia areata, and targeting them may lead to new treatments.
11 citations
,
March 2020 in “Immunology” Human prenatal skin develops an immune network early on that helps with skin formation and healing without scarring.
191 citations
,
May 2018 in “British journal of dermatology/British journal of dermatology, Supplement” Alopecia areata is likely an autoimmune disease with unclear triggers, involving various immune cells and molecules, and currently has no cure.
139 citations
,
December 2020 in “Cell Stem Cell” Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.
23 citations
,
April 2021 in “Journal of Clinical Medicine” Frontal Fibrosing Alopecia's cause is unclear, affects mainly postmenopausal women, and current treatments focus on stopping hair loss rather than regrowth.
29 citations
,
June 2018 in “Scientific Reports” 15-lipoxygenase helps keep skin healthy by reducing inflammation.
2 citations
,
December 2011 in “Annales de Dermatologie et de Vénéréologie” 2011 dermatological research found new skin aging markers, hair loss causes, skin defense mechanisms, and potential for new treatments.
19 citations
,
November 2023 in “npj Regenerative Medicine” Synthetic melanin applied to skin speeds up wound healing.
2 citations
,
October 2015 in “Human Gene Therapy” The congress highlighted new gene therapy techniques and cell transplantation methods for treating diseases.
2 citations
,
March 2015 in “Expert opinion on orphan drugs” New treatments for hair loss show promise but need more research to confirm safety and effectiveness.
1160 citations
,
November 2018 in “Physiological Reviews” The document concludes that better targeted treatments are needed for wound healing, and single-cell technologies may improve cell-based therapies.
29 citations
,
May 2020 in “npj Regenerative Medicine” Immune cells help regulate hair growth, and better understanding this can improve hair loss treatments.
39 citations
,
January 2015 in “International journal for parasitology/International Journal for Parasitology” Epidermal keratinocytes start wound healing and inflammation after schistosome infection.
May 2009 in “The American Journal of Dermatopathology” Mast cells play a significant role in hair loss conditions like male pattern hair loss and alopecia areata.
19 citations
,
January 2021 in “Experimental dermatology” Acne inversa is an epithelial-driven disease where inflammation is caused by cyst rupture, and treatments should focus on preventing tendril growth for better results.
139 citations
,
February 2010 in “The journal of allergy and clinical immunology/Journal of allergy and clinical immunology/The journal of allergy and clinical immunology” Transplant success has improved with better immunosuppressive drugs and donor matching.
18 citations
,
May 2018 in “International Journal of Molecular Sciences” Human body's immune cells are more common in the layer of fat just beneath the skin than in deeper fat layers.
59 citations
,
July 2015 in “Journal of Immunology” Certain proteins, caspases-1 and -11, are important in the early development of skin inflammation in mice.
9 citations
,
September 2009 in “PubMed” Antigen presenting cells around hair follicles are crucial in SLE-related hair loss.
44 citations
,
June 2023 in “Cell Reports” IL-1 promotes fat cell growth in skin, while WNT inhibits it and encourages scar formation.
55 citations
,
August 2024 in “Heliyon” Stem cell transplantation shows promise for treating diseases but faces challenges like safety, ethics, and cost.
13 citations
,
October 2021 in “International Journal of Molecular Sciences” The HATMSC1 cell line from fat tissue can produce helpful factors for regenerative and immune therapies.
91 citations
,
January 2010 in “Journal of Allergy and Clinical Immunology” NK cells play a role in skin diseases like eczema and psoriasis.
97 citations
,
May 2019 in “Frontiers in Cell and Developmental Biology” Abnormal ECM and immune cell interactions can cause skin diseases.
33 citations
,
January 2018 in “Blood” Ruxolitinib helps protect skin stem cells and keeps skin healthy in mice with skin GVHD.
1 citations
,
January 2025 in “Advances in Wound Care” Dermal sheath cells help heal wounds by showing both skin and connective tissue traits.
42 citations
,
December 2011 in “The journal of immunology/The Journal of immunology” RANKL causes lymph nodes to grow by making certain cells multiply.
3 citations
,
March 2024 in “Viruses” γδ T cells are essential for wound healing after poxvirus infection.
260 citations
,
January 2020 in “Nature” Stress can cause hair to turn gray by depleting stem cells.