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Cyclosporin A, a drug, reduces TGF-β2 expression in skin cells, potentially causing excessive hair growth through a process involving the calcineurin/NFAT pathway.

Blocking JAK1 or JAK3 helps reverse hair loss in a mouse model of alopecia areata.

Super-enhancers control CD25 expression in specific cell types, affecting immune function.

CAR-T therapy offers hope for children with hard-to-treat blood cancers.

Skin cancer often starts from Lgr5+ progenitor cells.

CI-1033 causes skin lesions in rats, similar to humans, due to EGF receptor inhibition.

Trodelvy™ helped some patients with advanced breast cancer, but had side effects.

A woman with alopecia regrew her hair after taking a higher dose of tocilizumab.

Targeting Vδ1+T-cells may help treat alopecia areata.

Loss of Desmocollin 3 in mice causes skin blisters and hair loss.

Targeting ornithine decarboxylase can help prevent skin cancer.

TAGX-0003 protected hair follicles and reversed alopecia areata in a mouse model.

Tofacitinib and low-dose IL-2 may help maintain hair regrowth in alopecia areata without ongoing treatment.

Mutations in the PADI3 gene may cause central centrifugal cicatricial alopecia in women of African ancestry.

Krt15+ cells in mice can resist radiation, regenerate tissue, and start tumors, suggesting new cancer treatment targets.

Tcf3 and Lef1 are key in deciding skin stem cell roles.

Modulating the BTNL2 pathway can prevent hair loss in mice.

Treg cell-based therapies might help treat hair loss from alopecia areata, but more research is needed to confirm safety and effectiveness.

Identical p53 gene mutations in different cancers suggest the need for careful treatment.

Scientists found a new type of skin cell that could help with skin repair and these cells work better with a certain protein.

Overexpressing Merkel cell virus proteins in human hair follicles can create clusters of cells that resemble Merkel cell cancer.

Mutations in the PADI3 gene are linked to a higher risk of scarring hair loss in women of African descent.

MC-DNA vector-based gene therapy can temporarily treat CBS deficiency in mice.

TCDD reduces EGF receptors in the liver, affecting growth and development.

CTCF protein is essential for skin and hair follicle development in mice.

Mouse skin cancer progression involves a unique group of cells marked by ABCG2 and MTS24.

Increased regulatory T cell activity may lead to better outcomes in acute diffuse and total alopecia.