October 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Immune cells are essential for early hair and skin development and healing.
April 2023 in “Dermatology practical & conceptual” Lenalidomide helps hair follicle stem cells turn into melanocytes, which may improve repigmentation in vitiligo.
291 citations
,
October 2005 in “Proceedings of the National Academy of Sciences of the United States of America” Adult stem cells from rat whisker follicles can regenerate hair follicles and sebaceous glands.
153 citations
,
October 2007 in “Cell Stem Cell” New research suggests that skin cell renewal may not require a special type of cell previously thought to be essential.
143 citations
,
September 2008 in “Experimental gerontology” Skin aging is due to impaired stem cell mobilization or fewer responsive stem cells.
95 citations
,
July 2010 in “Genes & development” Notch/CSL signaling controls hair follicle differentiation through Wnt5a and FoxN1.
84 citations
,
January 2008 in “Cold Spring Harbor Symposia on Quantitative Biology” Skin stem cells help maintain skin health, grow hair, and heal wounds.
61 citations
,
September 2008 in “Stem Cells” Most hair follicle stem cells do not protect their DNA by dividing it unevenly.
57 citations
,
March 2018 in “International Journal of Molecular Sciences” The extracellular matrix is crucial for controlling skin stem cell behavior and health.
38 citations
,
June 2017 in “The Journal of Dermatology” Aging in hair follicle stem cells leads to hair graying, thinning, and loss.
30 citations
,
April 2013 in “Journal of Investigative Dermatology” Radiation mainly affects keratinocyte stem cells, not melanocyte stem cells, causing hair to gray.
29 citations
,
March 2012 in “Stem Cell Research & Therapy” Some stem cells in the body rarely divide, which could help create better treatments for diseases and aging.
27 citations
,
June 2013 in “Genes & development” Cav1.2 affects hair growth and could be a target for hair loss treatments.
24 citations
,
July 2018 in “Stem cells” Runx1 controls fat-related genes important for normal and cancer cell growth, affecting skin and hair cell behavior.
24 citations
,
May 2016 in “Stem Cell Reviews and Reports” The document concludes that understanding how adult stem and progenitor cells move is crucial for tissue repair and developing cell therapies.
15 citations
,
February 2009 in “Cell Stem Cell” The document concludes that certain chemicals can help maintain stem cell pluripotency and that understanding cell states is crucial for tissue regeneration.
14 citations
,
January 2018 in “Scientific reports” Bioluminescence imaging can track hair follicle cells and help study hair regrowth.
12 citations
,
May 2019 in “Stem cell reviews” Fetal-maternal stem cells in a mother's hair can help with tissue repair and regeneration long after childbirth.
4 citations
,
January 2013 in “Advances in Experimental Medicine and Biology” Certain transcription factors are key in controlling skin stem cell behavior and could impact future treatments for skin repair and hair loss.
August 2022 in “Research Square (Research Square)” Implanted special stem cells from hair follicles helped heal wounds faster and with less scarring in mice.
Skin stem cells are crucial for maintaining and repairing skin, with potential for treating skin disorders and improving wound healing.
499 citations
,
September 2011 in “Cell” Fat-related cells are important for initiating hair growth.
363 citations
,
March 2017 in “Nature Communications” Stem cells help heal wounds by rapidly dividing and migrating to the wound edge.
305 citations
,
June 2012 in “Nature” Hair regeneration needs dynamic cell behavior and mesenchyme presence for stem cell activation.
298 citations
,
January 2014 in “BioMed Research International” Stem cell-derived conditioned medium shows promise for treating various medical conditions but requires standardized production and further validation.
254 citations
,
January 2012 in “Nature Reviews Molecular Cell Biology” Stem cell offspring help control their parent stem cells, affecting tissue health, healing, and cancer.
232 citations
,
October 2015 in “International journal of molecular sciences” Stem cells are crucial for skin repair and new treatments for chronic wounds.
211 citations
,
November 2018 in “Nature Cell Biology” Stem cells help heal skin wounds by moving and changing roles, working with other cells, and needing more research on their activation and behavior.
211 citations
,
May 2018 in “Trends in cell biology” Different types of skin cells play specific roles in development, healing, and cancer.
211 citations
,
April 2013 in “Development” More dermal papilla cells in hair follicles lead to larger, healthier hair, while fewer cells cause hair thinning and loss.