May 1991 in “Current problems in dermatology” Skin issues can indicate immune system problems.
1 citations
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October 2024 in “Journal of Clinical Immunology” Vaccines work well in Netherton syndrome patients, similar to healthy people.
103 citations
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January 2011 in “Blood” Thymus transplantation successfully restored immune function in infants with FOXN1 deficiency.
9 citations
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April 2006 in “Experimental and Clinical Endocrinology & Diabetes” A woman's small, unnoticed adrenal mass turned out to be a rare non-Hodgkin's lymphoma, treated successfully with surgery and therapy.
January 2026 in “Immunological Reviews” Females generally have stronger immune responses than males due to the X chromosome.
July 2023 in “Journal of allergy and clinical Immunology. Global” A 10-month-old boy with a rare combination of genetic conditions has severe immune deficiency and treatment challenges.
3 citations
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May 2023 in “Biomedicines” PCOS causes infertility mainly due to hormonal imbalances, insulin resistance, and chronic inflammation.
98 citations
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March 2019 in “Frontiers in immunology” Damaging mutations in NFKB2 cause a severe and distinct form of primary immunodeficiency with early-onset and often ACTH-deficiency.
37 citations
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April 2018 in “Journal of Allergy and Clinical Immunology” A mutation in the IKZF1 gene causes immune system overactivity, linked to autoimmune diseases like lupus.
40 citations
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January 1996 in “Journal of Dermatological Treatment” Antimicrobial lotion reduces inflammation and increases hair density in hair loss patients.
30 citations
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January 2021 in “Journal of Clinical Immunology” FOXN1 mutations can cause varying immune and physical issues, with severity influenced by gene activity and possibly other factors.
149 citations
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July 2002 in “Dermatologic clinics” Patients with certain skin symptoms and high ANA titers should be monitored for potential systemic lupus.
26 citations
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June 2018 in “The journal of immunology/The Journal of immunology” AIRE-deficient rats developed severe autoimmune disease similar to APECED, useful for testing treatments.
May 2022 in “Gastroenterology” Targeting NETs may help reduce fibrosis in Crohn's disease.
42 citations
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October 2009 in “The journal of investigative dermatology/Journal of investigative dermatology” Mutations in the KRT85 gene cause hair and nail problems.
17 citations
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January 2011 in “Skin Research and Technology” Hair from people with seborrheic dermatitis is thicker scaled, more damaged, and thinner than healthy hair, and atomic force microscopy can help monitor the condition.
223 citations
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September 2018 in “Rheumatology” JAK inhibitors are effective in treating various immune-related diseases, not just rheumatoid arthritis.
Botulinum toxin type A significantly reduces scalp psoriasis severity compared to placebo.
Melatonin can improve treatment and extend remission for certain skin conditions.
102 citations
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December 2017 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings” Restoring hair bulb immune privilege is crucial for managing alopecia areata.
4 citations
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February 2007 in “Journal of the European Academy of Dermatology and Venereology” The study suggests silicon might be important for healthy hair, as less silicon was found in people with hair loss.
November 2025 in “Frontiers in Medicine” Baseline severity and relapse history affect alopecia areata treatment and recurrence.
May 2023 in “Sučasna pedìatrìâ. Ukraïna” An 11-year-old child with total hair loss may have a genetic autoimmune disease, and the outlook for hair regrowth is not good.
March 2016 in “International Journal of Infectious Diseases” Peginterferon alpha-2a effectively treats acute hepatitis C in hemodialysed patients, despite some side effects.
18 citations
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August 2024 in “eLife” JAK inhibition may help manage autoimmune conditions in Down syndrome.
16 citations
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December 2021 in “Frontiers in Endocrinology” Sex hormones may affect COVID-19 severity, with estrogen possibly reducing risk and testosterone potentially increasing it.
June 2020 in “Comparative medicine” NSG mice had the most mites, and genetic factors affect immune response and susceptibility.
5 citations
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January 2016 in “Skin appendage disorders” Frontal fibrosing alopecia might be linked to autoimmune diseases.
66 citations
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July 2010 in “Journal of Proteome Research” Trichohyalin may trigger the immune response causing alopecia areata.
561 citations
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April 2003 in “Journal of Investigative Dermatology” CD34 is a marker for isolating stem-like cells in mouse hair follicles.