85 citations
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March 2008 in “Journal of Cell Science” The mutation causing Hutchinson-Gilford progeria syndrome leads to severe skin problems and early death in mice.
31 citations
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April 2004 in “Journal of Investigative Dermatology” A new mouse gene, Keratin 17n, is mainly found in nail tissue and may explain why mice without Keratin 17 don't have nail issues.
30 citations
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February 2010 in “The journal of investigative dermatology/Journal of investigative dermatology” Plet-1 protein helps hair follicle cells move and stick to tissues.
24 citations
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January 2011 in “Sexual Development” Intersex frogs have different brain gene activity related to sex and thyroid hormones.
21 citations
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May 2016 in “Experimental and Therapeutic Medicine” MMP-2 and MMP-9 help hair grow, while their inhibitors peak when hair growth slows.
11 citations
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July 2004 in “Journal of Investigative Dermatology” Certain tyrosine kinases may regulate hair growth and could help develop hair loss treatments.
1 citations
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June 2021 in “Singapore Medical Journal” Dutasteride and finasteride can help increase hair growth gene expression but need further improvement.
January 2026 in “Bioengineering” Recombinant collagen is promising for biomaterials, pharmaceuticals, and skincare due to its benefits and potential improvements.
July 2023 in “Biomolecules” The new "whisker follicle microinjection assay" can test how different biomolecules affect hair growth and color.
198 citations
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March 1999 in “Journal of Investigative Dermatology” Keratin 15 helps maintain tissue integrity and is reduced in activated keratinocytes.
72 citations
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July 2002 in “Journal of Investigative Dermatology” Desmoglein 1 can partly make up for the loss of Desmoglein 3 in hair adhesion but not in mucous membranes.
35 citations
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June 2012 in “PloS one” Keratin 15 expression in skin cells is regulated by two mechanisms involving PKC/AP-1 and FOXM1.
26 citations
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May 2016 in “Journal of biological chemistry/The Journal of biological chemistry” sPLA2-IIE is crucial for normal hair follicle structure and skin health.
21 citations
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January 2023 in “International Journal of Molecular Sciences” S100A6 protein is linked to disease progression, especially in cancers.
14 citations
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January 2006 in “Journal of Investigative Dermatology” Transferrin receptor expression increases iron in mouse skin cells without causing damage.
9 citations
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April 2019 in “Bioscience, biotechnology, and biochemistry” Ten miRNAs may play key roles in starting secondary hair follicle development in sheep foetuses.
5 citations
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January 2024 in “Science Advances” Touch dome keratinocytes in adult skin have traits of different skin cell types.
5 citations
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May 2023 in “Frontiers in Cell and Developmental Biology” Integrin α6 helps identify different neural crest cell types in the skin.
5 citations
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August 2011 in “Journal of Dermatological Science” Dentin sialoprotein and phosphophoryn are present in rodent hair follicles and may help hair growth and development.
February 2024 in “Biomedicines” Pregnant women with PCOS have higher levels of Neurokinin B in the placenta, especially with female babies.
132 citations
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February 2002 in “Journal of Biological Chemistry” HOXC13 is crucial for regulating hair keratin genes in hair follicles.
119 citations
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August 2010 in “Journal of Investigative Dermatology” Increased 11β-HSD1 activity in skin may contribute to aging and could be targeted to reduce aging effects.
25 citations
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June 2017 in “Journal of steroid biochemistry and molecular biology/The Journal of steroid biochemistry and molecular biology” VDR regulation varies by tissue and is crucial for its biological functions.
May 2023 in “International journal of molecular sciences” The ABCA4 gene protects hair follicle stem cells from toxic vitamin A byproducts.
July 2025 in “Reproductive Biology and Endocrinology” Early androgen exposure affects hormone receptor expression in adult female rats' brains, but not in males.
231 citations
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October 1999 in “Journal of Clinical Investigation” Activating the Sonic hedgehog gene in mice can start the hair growth phase.
149 citations
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June 2010 in “The FASEB journal” miR-31 regulates hair growth by controlling gene expression in hair follicles.
21 citations
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April 2016 in “International Journal of Oncology” GnRH treatment can reduce breast cancer cell invasion.
15 citations
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March 2000 in “The journal of investigative dermatology/Journal of investigative dermatology” As skin cells mature, vitamin D receptor levels decrease while retinoid X receptor α levels increase.
12 citations
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January 2022 in “Cells” Dermal papilla cell vesicles can boost hair growth genes in fat stem cells.